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NCT06111339 · ClinicalTrials.gov registry record · Phase 2
Ketamine for OUD and Suicidal Ideation in the ED
A Phase 2 study, sponsored by Brigham and Women's Hospital.
- Terminated
- Registry status
- Phase 2
- Development phase
- 4
- Enrollment target
NCT06111339: Clinical Trial Phase 2 study, sponsored by Brigham and Women's Hospital.
NCT06111339 is a Phase 2 study that was terminated before completion, run by Brigham and Women's Hospital. The registered enrollment target is 4 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06111339, a Phase 2 study, was terminated before completion, sponsored by Brigham and Women's Hospital.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 4 participants
- Enrollment target
Study Summary
This is a pilot, double-blind, placebo-controlled randomized clinical trial of individuals with opioid use disorder (OUD) with suicidal ideation in the emergency department (ED) to receive either a single infusion of ketamine 0.8mg/kg (n=25) or saline placebo (n=25). The primary aim is to evaluate the safety of the ketamine treatment. The secondary aim is to determine the preliminary efficacy of opioid- and suicide-related outcomes.
Primary Outcome
For suicidal ideation, the Columbia Suicide Severity Rating Scale (C-SSRS), which is a 5-item tool, will be used to assess suicidal ideation.
Interventions
- DRUG Ketamine
- OTHER Saline Solution
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2024-06-14 |
| Est. Completion | 2025-03-31 |
| Phase | Phase 2 |
Why NCT06111339 stopped before completion
NCT06111339 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 2 interventions - of which Ketamine is the first listed.
NCT06111339 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06111339 about?
NCT06111339 is a clinical study titled "Ketamine for OUD and Suicidal Ideation in the ED". This is a pilot, double-blind, placebo-controlled randomized clinical trial of individuals with opioid use disorder (OUD) with suicidal ideation in the emergency department (ED) to receive either a single infusion of ketamine 0.8mg/kg (n=25) or saline placebo (n=25). The primary aim is to evaluate t...
What is the current status of trial NCT06111339?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 4 participants. The study started on 2024-06-14. Estimated completion is 2025-03-31.
What interventions are being tested in trial NCT06111339?
The interventions under investigation include: Ketamine (DRUG), Saline Solution (OTHER).
Who is sponsoring clinical trial NCT06111339?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06111339's enrollment target sits among peer trials
4 2001st of 2000 the lowest of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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