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NCT07619508 · ClinicalTrials.gov registry record

Tirzepatide vs Semaglutide in Individuals at Cardiovascular Risk But Without Diabetes.

A clinical trial, sponsored by Brigham and Women's Hospital.

Completed
Registry status
100,000
Enrollment target

NCT07619508: Completed study, sponsored by Brigham and Women's Hospital.

NCT07619508 is a clinical trial that has completed, run by Brigham and Women's Hospital. The registered enrollment target is 100,000 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07619508 has completed, sponsored by Brigham and Women's Hospital.

COMPLETED
Registry status
100,000 participants
Enrollment target

Study Summary

Investigators are building an empirical evidence base for real world data through large-scale emulation of randomized controlled trials. The investigators' goal is to understand for what types of clinical questions real world data analyses can be conducted with confidence and how to implement such studies.

Primary Outcome

To evaluate the comparative effect of tirzepatide vs injectable semaglutide on the composite of death, myocardial infarction, or stroke in patients at cardiovascular risk with overweight or obesity but without diabetes treated in clinical practice.

Interventions

  • DRUG Tirzepatide
  • DRUG Semaglutide

Trial Details

FieldValue
Enrollment Target 100,000 participants
Start Date 2026-02-10
Est. Completion 2026-06-01
Brigham and Women's Hospital

937 total trials

What the finished NCT07619508 record still lists

NCT07619508 is an observational study that tracks outcomes without assigning an intervention. Its 100,000 participants enrollment target places it among the larger protocols in the corpus.

The record links to 0 conditions, and to 2 interventions - of which Tirzepatide is the first listed.

NCT07619508 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07619508 about?

NCT07619508 is a clinical study titled "Tirzepatide vs Semaglutide in Individuals at Cardiovascular Risk But Without Diabetes.". Investigators are building an empirical evidence base for real world data through large-scale emulation of randomized controlled trials. The investigators' goal is to understand for what types of clinical questions real world data analyses can be conducted with confidence and how to implement such s...

What is the current status of trial NCT07619508?

This trial is currently completed. The enrollment target is 100,000 participants. The study started on 2026-02-10. Estimated completion is 2026-06-01.

What interventions are being tested in trial NCT07619508?

The interventions under investigation include: Tirzepatide (DRUG), Semaglutide (DRUG).

Who is sponsoring clinical trial NCT07619508?

This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.

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Source: ClinicalTrials.gov NCT07619508, the US trial registry maintained by the National Library of Medicine. NCT07619508 (large enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.