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NCT07534774 · ClinicalTrials.gov registry record · NA
Pilot Study of Real-Time Blood Pressure Decision Support During Cesarean Delivery Under Spinal Anesthesia
A NA study, sponsored by Brigham and Women's Hospital.
- Completed
- Registry status
- NA
- Development phase
- 20
- Enrollment target
NCT07534774: Completed NA study, sponsored by Brigham and Women's Hospital.
NCT07534774 is a NA study that has completed, run by Brigham and Women's Hospital. The registered enrollment target is 20 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07534774, a NA study, has completed, sponsored by Brigham and Women's Hospital.
- COMPLETED
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
Study Summary
This single-center, open-label pilot study evaluates a clinician-facing decision-support algorithm that displays real-time forecasts of maternal mean arterial pressure (MAP), a measure of blood pressure, during elective cesarean delivery under spinal anesthesia. The display provides 1-, 2-, and 3-minute MAP forecasts from the time of spinal anesthesia administration until delivery or up to 20 minutes, whichever occurs first. Clinicians continue to manage blood pressure according to usual institutional practice, including phenylephrine infusion and bolus dosing, and retain full autonomy over treatment decisions; the study display does not provide dosing recommendations. The primary objective is to assess the prospective accuracy of short-horizon MAP forecasts. Secondary outcomes assess intraoperative hypotension burden and phenylephrine exposure during the observation window, including exploratory comparison with matched nonconcurrent controls.
Primary Outcome
Patient-level mean root mean square error (RMSE) between algorithm-predicted and observed maternal mean arterial pressure (MAP) for the 1-minute forecast horizon using minute-level intraoperative data.
Interventions
- OTHER ARX Decision-Support Display
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2025-06-16 |
| Est. Completion | 2025-07-16 |
| Phase | NA |
What the finished NCT07534774 record still lists
NCT07534774 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 1 intervention - of which ARX Decision-Support Display is the first listed.
NCT07534774 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07534774 about?
NCT07534774 is a clinical study titled "Pilot Study of Real-Time Blood Pressure Decision Support During Cesarean Delivery Under Spinal Anesthesia". This single-center, open-label pilot study evaluates a clinician-facing decision-support algorithm that displays real-time forecasts of maternal mean arterial pressure (MAP), a measure of blood pressure, during elective cesarean delivery under spinal anesthesia. The display provides 1-, 2-, and 3-mi...
What is the current status of trial NCT07534774?
This trial is currently completed. It is a NA study. The enrollment target is 20 participants. The study started on 2025-06-16. Estimated completion is 2025-07-16.
What interventions are being tested in trial NCT07534774?
The interventions under investigation include: ARX Decision-Support Display (OTHER).
Who is sponsoring clinical trial NCT07534774?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07534774's enrollment target sits among peer trials
20 1768th of 2000 higher than 140 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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