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NCT01653678 · ClinicalTrials.gov registry record · NA
Vitamin D and Omega-3 Hypertension Trial (VITAL Hypertension)
A NA study of Hypertension, sponsored by Brigham and Women's Hospital.
- Active
- Registry status
- NA
- Development phase
- 25,875
- Enrollment target
- 1
- Study location
NCT01653678: Active NA study of Hypertension, sponsored by Brigham and Women's Hospital.
NCT01653678 is a NA study of Hypertension that is active but no longer recruiting, run by Brigham and Women's Hospital. The registered enrollment target is 25,875 participants, above the 3,452-participant average among 470 other Hypertension trials with a reported enrollment target (650% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01653678, a NA study of Hypertension, is active but no longer recruiting, sponsored by Brigham and Women's Hospital.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 25,875 participants
- Enrollment target
- 1
- Study location
Study Summary
The VITamin D and OmegA-3 TriaL (VITAL; NCT 01169259) is an ongoing randomized clinical trial in 25,875 U.S. men and women investigating whether taking daily dietary supplements of vitamin D3 (2000 IU) or omega-3 fatty acids (Omacor® fish oil, 1 gram) reduces the risk of developing cancer, heart disease, and stroke in people who do not have a prior history of these illnesses. The VITAL Hypertension ancillary study is being conducted among participants in VITAL and will examine whether vitamin D or omega-3 fatty acids are related to changes in blood pressure and hypertension.
Primary Outcome
Change in 24-hour ambulatory blood pressure measurements among a subcohort of approximately 1,000 participants.
Conditions Studied
Interventions
- DRUG Omega-3 fatty acids (fish oil)
- DIETARY_SUPPLEMENT Vitamin D-3 (cholecalciferol), 2000 IU
- DIETARY_SUPPLEMENT Vitamin D placebo
- DRUG Fish oil placebo
Study Locations (1)
Massachusetts
- Brigham and Women's Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25,875 participants |
| Start Date | 2011-11 |
| Est. Completion | 2026-06 |
| Phase | NA |
What the registry record for NCT01653678 still lists
NCT01653678 is an interventional study that assigns participants to a tested intervention. Its 25,875 participants enrollment target places it among the larger protocols in the corpus, above the 3,452-participant average among 470 other Hypertension trials with a reported enrollment target (650% higher).
The record links to 1 condition, with Hypertension appearing as the primary indexed condition, and to 4 interventions - of which Omega-3 fatty acids (fish oil) is the first listed.
NCT01653678 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT01653678 about?
NCT01653678 is a clinical study titled "Vitamin D and Omega-3 Hypertension Trial (VITAL Hypertension)". The VITamin D and OmegA-3 TriaL (VITAL; NCT 01169259) is an ongoing randomized clinical trial in 25,875 U.S. men and women investigating whether taking daily dietary supplements of vitamin D3 (2000 IU) or omega-3 fatty acids (Omacor® fish oil, 1 gram) reduces the risk of developing cancer, heart dis...
What is the current status of trial NCT01653678?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 25,875 participants. The study started on 2011-11. Estimated completion is 2026-06.
What conditions does trial NCT01653678 study?
This clinical trial studies the following conditions: Hypertension.
What interventions are being tested in trial NCT01653678?
The interventions under investigation include: Omega-3 fatty acids (fish oil) (DRUG), Vitamin D-3 (cholecalciferol), 2000 IU (DIETARY_SUPPLEMENT), Vitamin D placebo (DIETARY_SUPPLEMENT), Fish oil placebo (DRUG).
Who is sponsoring clinical trial NCT01653678?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01653678 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Hypertension
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01653678's enrollment target sits among peer trials
25,875 10th of 470 higher than 461 of 470 other Hypertension trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hypertension trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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