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NCT07441265 · ClinicalTrials.gov registry record · NA
Does Circadian Misalignment Have Sex-Specific Effects on Metabolism?
A NA study, sponsored by Brigham and Women's Hospital.
- Not yet
- Registry status
- NA
- Development phase
- 36
- Enrollment target
NCT07441265: Clinical Trial NA study, sponsored by Brigham and Women's Hospital.
NCT07441265 is a NA study that has not yet begun recruiting, run by Brigham and Women's Hospital. The registered enrollment target is 36 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07441265, a NA study, has not yet begun recruiting, sponsored by Brigham and Women's Hospital.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 36 participants
- Enrollment target
Study Summary
This study will test whether biological sex influences how the body responds to circadian misalignment-a mismatch between the internal body clock and the timing of sleep and eating (as can occur with shift work or jet lag). Researchers will examine how circadian misalignment affects appetite regulation (hunger/fullness) and glucose metabolism (blood sugar control), and whether these effects differ between females and males. Findings may help inform more personalized shift work schedules and targeted strategies to reduce metabolic health risks and sex-related differences in clinical care.
Primary Outcome
Differences of 24-h circulating leptin levels on the test days in the two experimental conditions
Interventions
- BEHAVIORAL Day shift
- BEHAVIORAL Night shift
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2026-10-01 |
| Est. Completion | 2030-09-30 |
| Phase | NA |
What is known before NCT07441265 opens enrollment
NCT07441265 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 2 interventions - of which Day shift is the first listed.
NCT07441265 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07441265 about?
NCT07441265 is a clinical study titled "Does Circadian Misalignment Have Sex-Specific Effects on Metabolism?". This study will test whether biological sex influences how the body responds to circadian misalignment-a mismatch between the internal body clock and the timing of sleep and eating (as can occur with shift work or jet lag). Researchers will examine how circadian misalignment affects appetite regulat...
What is the current status of trial NCT07441265?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 36 participants. The study started on 2026-10-01. Estimated completion is 2030-09-30.
What interventions are being tested in trial NCT07441265?
The interventions under investigation include: Day shift (BEHAVIORAL), Night shift (BEHAVIORAL).
Who is sponsoring clinical trial NCT07441265?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07441265's enrollment target sits among peer trials
36 1541st of 2000 higher than 437 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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