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NCT07249840 · ClinicalTrials.gov registry record · Phase 1

Ropeginterferon for High Risk JAK2 Clonal Hematopoiesis

A Phase 1 study, sponsored by Brigham and Women's Hospital.

Not yet
Registry status
Phase 1
Development phase
12
Enrollment target

NCT07249840 is a Phase 1 study that has not yet begun recruiting, run by Brigham and Women's Hospital. The registered enrollment target is 12 participants.

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The verdict

NCT07249840, a Phase 1 study, has not yet begun recruiting, sponsored by Brigham and Women's Hospital.

NOT YET RECRUITING
Registry status
Phase 1
Development phase
12 participants
Enrollment target

Study Summary

The goal of this clinical trial is to learn if the drug ropeginterferon alfa-2b can be used safely to treat patients with a JAK2 mutation and high risk features, but do not yet have a myeloproliferative neoplasm. The main questions it aims to answer are: * Can we enroll 12 patients with JAK2 mutations and high risk features without a myeloproliferative neoplasm on a clinical trial evaluating the drug ropeginterferon? * Is ropeginterferon safe to use in these patients? Participants will: * Receive ropeginterferon as an injection under the skin once every 4 weeks * Visit the clinic every 1-3 months for checkups and tests

Interventions

  • DRUG Ropeginterferon

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2026-08
Est. Completion 2030-08
Phase Phase 1

Sponsor

Brigham and Women's Hospital

937 total trials

What the Registry Record Tells You About NCT07249840

The ClinicalTrials.gov registry entry for NCT07249840 describes a study currently listed as not yet recruiting, categorized as Phase 1. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Brigham and Women's Hospital, which has 937 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Ropeginterferon is the first listed.

NCT07249840 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT07249840 about?

NCT07249840 is a clinical study titled "Ropeginterferon for High Risk JAK2 Clonal Hematopoiesis". The goal of this clinical trial is to learn if the drug ropeginterferon alfa-2b can be used safely to treat patients with a JAK2 mutation and high risk features, but do not yet have a myeloproliferative neoplasm. The main questions it aims to answer are: * Can we enroll 12 patients with JAK2 mutati...

What is the current status of trial NCT07249840?

This trial is currently not yet recruiting. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2026-08. Estimated completion is 2030-08.

What interventions are being tested in trial NCT07249840?

The interventions under investigation include: Ropeginterferon (DRUG).

Who is sponsoring clinical trial NCT07249840?

This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.