Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06052865 · ClinicalTrials.gov registry record · NA
Serial Brain MRI in Hospitalized Preterm Infants
A NA study of Preterm Birth Complication, sponsored by Brigham and Women's Hospital.
- Active
- Registry status
- NA
- Development phase
- 75
- Enrollment target
- 1
- Study location
NCT06052865: Active NA study of Preterm Birth Complication, sponsored by Brigham and Women's Hospital.
NCT06052865 is a NA study of Preterm Birth Complication that is active but no longer recruiting, run by Brigham and Women's Hospital. The registered enrollment target is 75 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06052865, a NA study of Preterm Birth Complication, is active but no longer recruiting, sponsored by Brigham and Women's Hospital.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 75 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this research study is to use serial magnetic resonance imaging (MRI) to define the timing and factors associated with brain injury as well as the pattern of brain growth of very preterm infants during hospitalization in the neonatal intensive care unit (NICU). In addition, the goal is to utilize early MRI to risk-stratify preterm infants and tailor rehabilitative interventions according to risk in order to explore associations between NICU rehabilitative intervention and short- and long-term outcomes of preterm infants.
Primary Outcome
Term equivalent brain MRIs will be assessed to characterize brain injury, including elements of: white matter abnormalities, cortical gray matter abnormalities, deep gray matter abnormalities, and cerebellar abnormalities. A total (global) brain injury score will be calculated as the sum of regional brain abnormalities total scores, with higher scores indicating more advanced level of injury as per the established scoring system for hospitalized preterm infants published by Kidokoro et al. The s
Conditions Studied
Interventions
- BEHAVIORAL SENSE-plus: The Supporting and Enhancing NICU Sensory Experiences 2nd Edition (SENSE II) program
- BEHAVIORAL SENSE: The Supporting and Enhancing NICU Sensory Experiences 2nd Edition (SENSE II) program
- OTHER Reference/ Standard of care
Study Locations (1)
Massachusetts
- Brigham and Women's Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 75 participants |
| Start Date | 2020-09-14 |
| Est. Completion | 2029-09-14 |
| Phase | NA |
What the registry record for NCT06052865 still lists
NCT06052865 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 75 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower).
The record links to 1 condition, with Preterm Birth Complication appearing as the primary indexed condition, and to 3 interventions - of which SENSE-plus: The Supporting and Enhancing NICU Sensory Experiences 2nd Edition (SENSE II) program is the first listed.
NCT06052865 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT06052865 about?
NCT06052865 is a clinical study titled "Serial Brain MRI in Hospitalized Preterm Infants". The purpose of this research study is to use serial magnetic resonance imaging (MRI) to define the timing and factors associated with brain injury as well as the pattern of brain growth of very preterm infants during hospitalization in the neonatal intensive care unit (NICU). In addition, the goal i...
What is the current status of trial NCT06052865?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 75 participants. The study started on 2020-09-14. Estimated completion is 2029-09-14.
What conditions does trial NCT06052865 study?
This clinical trial studies the following conditions: Preterm Birth Complication.
What interventions are being tested in trial NCT06052865?
The interventions under investigation include: SENSE-plus: The Supporting and Enhancing NICU Sensory Experiences 2nd Edition (SENSE II) program (BEHAVIORAL), SENSE: The Supporting and Enhancing NICU Sensory Experiences 2nd Edition (SENSE II) program (BEHAVIORAL), Reference/ Standard of care (OTHER).
Who is sponsoring clinical trial NCT06052865?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06052865 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Preterm Birth Complication
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06052865's enrollment target sits among peer trials
75 1069th of 2000 higher than 919 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01535430 · 75 participants
Assessment of Eloquent Function in Brain Tumor Patients
- NCT01542879 · 75 participants · Phase 1
Development of Radiation Free Whole Body Magnetic Resonance (MR) Imaging Technique for Staging Children With Cancer
- NCT02232191 · 75 participants · Phase 2
Immunologic Response to Pneumococcal Polysaccharide Vaccine in Splenic Injury Patients
- NCT02754544 · 75 participants · NA
Electrocorticography in Mapping Functional Brain Areas During Surgery in Patients With Brain Tumors
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI