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NCT06854211 · ClinicalTrials.gov registry record · Early Phase 1
Impacts of Opioids on Respiratory Drive During Sleep
A Early Phase 1 study, sponsored by Brigham and Women's Hospital.
- Not yet
- Registry status
- Early Phase 1
- Development phase
- 26
- Enrollment target
NCT06854211: Clinical Trial Early Phase 1 study, sponsored by Brigham and Women's Hospital.
NCT06854211 is a Early Phase 1 study that has not yet begun recruiting, run by Brigham and Women's Hospital. The registered enrollment target is 26 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (51% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06854211, a Early Phase 1 study, has not yet begun recruiting, sponsored by Brigham and Women's Hospital.
- NOT YET RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 26 participants
- Enrollment target
Study Summary
The investigators are studying the impact that opioids have on breathing during sleep in healthy participants and those diagnosed with obstructive sleep apnea.
Primary Outcome
The primary outcome, determining the change in ventilation in liters per minute, will be analyzed on both subpopulations (controls and people with obstructive sleep apnea) using generalized linear mixed models with treatment, period and sequence as fixed effects and a random effect of participant nested within sequence.
Interventions
- DRUG Placebo
- DRUG Morphine p.o.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 26 participants |
| Start Date | 2026-07-01 |
| Est. Completion | 2027-01-31 |
| Phase | Early Phase 1 |
What is known before NCT06854211 opens enrollment
NCT06854211 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 26 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (51% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT06854211 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06854211 about?
NCT06854211 is a clinical study titled "Impacts of Opioids on Respiratory Drive During Sleep". The investigators are studying the impact that opioids have on breathing during sleep in healthy participants and those diagnosed with obstructive sleep apnea.
What is the current status of trial NCT06854211?
This trial is currently not yet recruiting. It is a Early Phase 1 study. The enrollment target is 26 participants. The study started on 2026-07-01. Estimated completion is 2027-01-31.
What interventions are being tested in trial NCT06854211?
The interventions under investigation include: Placebo (DRUG), Morphine p.o. (DRUG).
Who is sponsoring clinical trial NCT06854211?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06854211's enrollment target sits among peer trials
26 977th of 2000 higher than 1,001 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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