Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05389904 · ClinicalTrials.gov registry record · NA
Pre-emptive Prevention for Patients at High Risk for Hospital-onset Clostridioides Difficile
A NA study of C. Difficile, sponsored by Brigham and Women's Hospital.
- Recruiting
- Registry status
- NA
- Development phase
- 300
- Enrollment target
- 1
- Study location
NCT05389904 is a NA study of C. Difficile that is actively recruiting participants, run by Brigham and Women's Hospital. The registered enrollment target is 300 participants. The trial reports 1 study location across 1 state.
The verdict
NCT05389904, a NA study of C. Difficile, is actively recruiting participants, sponsored by Brigham and Women's Hospital.
- RECRUITING
- Registry status
- NA
- Development phase
- 300 participants
- Enrollment target
- 1
- Study location
Study Summary
Clostridioides difficile (C. difficile) is the most common healthcare-associated pathogen, causing \>500,000 infections and \>29,000 deaths per year in the US. Traditional approaches to reduce hospital-onset CDI focus on identifying, isolating, and treating symptomatic patients to prevent transmission to other patients. Recent genomic epidemiology studies, however, suggest that most hospital-onset CDI cases are attributable to asymptomatic carriers who either progress from colonization to active infection themselves or transmit C. difficile to other patients while asymptomatic. This trial will evaluate an intervention to pre-emptively identify asymptomatic C. difficile carriers and then implement a patient-tailored prevention package to protect the carrier from progression to active infection and to prevent transmission from the carrier to other patients.
Conditions Studied
Interventions
- OTHER Arm 1: Routine care
- OTHER Arm 2: Preemptive C. difficile infection prevention bundle
Study Locations (1)
Massachusetts
- Brigham and Women's Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 300 participants |
| Start Date | 2022-07-25 |
| Est. Completion | 2026-08 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05389904
The ClinicalTrials.gov registry entry for NCT05389904 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 300 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Brigham and Women's Hospital, which has 937 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with C. Difficile appearing as the primary indexed condition, and to 2 interventions - of which Arm 1: Routine care is the first listed.
NCT05389904 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.
Frequently Asked Questions
What is clinical trial NCT05389904 about?
NCT05389904 is a clinical study titled "Pre-emptive Prevention for Patients at High Risk for Hospital-onset Clostridioides Difficile". Clostridioides difficile (C. difficile) is the most common healthcare-associated pathogen, causing \>500,000 infections and \>29,000 deaths per year in the US. Traditional approaches to reduce hospital-onset CDI focus on identifying, isolating, and treating symptomatic patients to prevent transmissi...
What is the current status of trial NCT05389904?
This trial is currently recruiting. It is a NA study. The enrollment target is 300 participants. The study started on 2022-07-25. Estimated completion is 2026-08.
What conditions does trial NCT05389904 study?
This clinical trial studies the following conditions: C. Difficile.
What interventions are being tested in trial NCT05389904?
The interventions under investigation include: Arm 1: Routine care (OTHER), Arm 2: Preemptive C. difficile infection prevention bundle (OTHER).
Who is sponsoring clinical trial NCT05389904?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05389904 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for C. Difficile
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.