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NCT07485179 · ClinicalTrials.gov registry record
Emulation of the KEYNOTE-042 (NCT02220894) Trial Using Specialty Oncology Electronic Health Records Databases
A clinical trial of Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC), sponsored by Brigham and Women's Hospital.
- Active
- Registry status
- 770
- Enrollment target
- 1
- Study location
NCT07485179: Active study of Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC), sponsored by Brigham and Women's Hospital.
NCT07485179 is a study of Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) that is active but no longer recruiting, run by Brigham and Women's Hospital. The registered enrollment target is 770 participants. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07485179, a study of Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC), is active but no longer recruiting, sponsored by Brigham and Women's Hospital.
- ACTIVE NOT RECRUITING
- Registry status
- 770 participants
- Enrollment target
- 1
- Study location
Study Summary
Investigators are building an empirical evidence base for real world data through large-scale emulation of randomized controlled trials. The investigators' goal is to understand for what types of clinical questions real world data analyses can be conducted with confidence and how to implement such studies.
Primary Outcome
Hazard ratio (95% CI) for overall survival
Conditions Studied
Interventions
- DRUG Initiation of pembrolizumab
- DRUG Initiation of chemotherapy
Study Locations (1)
Massachusetts
- Brigham and Women's Hospital - Somerville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 770 participants |
| Start Date | 2026-03-12 |
| Est. Completion | 2027-03-12 |
What the registry record for NCT07485179 still lists
NCT07485179 is an observational study that tracks outcomes without assigning an intervention. The registered 770 participants enrollment target is mid-sized for trials with a published cap.
The record links to 1 condition, with Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) appearing as the primary indexed condition, and to 2 interventions - of which Initiation of pembrolizumab is the first listed.
NCT07485179 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT07485179 about?
NCT07485179 is a clinical study titled "Emulation of the KEYNOTE-042 (NCT02220894) Trial Using Specialty Oncology Electronic Health Records Databases". Investigators are building an empirical evidence base for real world data through large-scale emulation of randomized controlled trials. The investigators' goal is to understand for what types of clinical questions real world data analyses can be conducted with confidence and how to implement such s...
What is the current status of trial NCT07485179?
This trial is currently active not recruiting. The enrollment target is 770 participants. The study started on 2026-03-12. Estimated completion is 2027-03-12.
What conditions does trial NCT07485179 study?
This clinical trial studies the following conditions: Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC).
What interventions are being tested in trial NCT07485179?
The interventions under investigation include: Initiation of pembrolizumab (DRUG), Initiation of chemotherapy (DRUG).
Who is sponsoring clinical trial NCT07485179?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07485179 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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