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NCT02641145 · ClinicalTrials.gov registry record · NA
Molecular Imaging of Primary Amyloid Cardiomyopathy
A NA study of Cardiomyopathy and Amyloidosis, Primary, sponsored by Brigham and Women's Hospital.
- Recruiting
- Registry status
- NA
- Development phase
- 171
- Enrollment target
- 1
- Study location
NCT02641145: Recruiting NA study of Cardiomyopathy and Amyloidosis, Primary, sponsored by Brigham and Women's Hospital.
NCT02641145 is a NA study of Cardiomyopathy and Amyloidosis, Primary that is actively recruiting participants, run by Brigham and Women's Hospital. The registered enrollment target is 171 participants, below the 550-participant average among 25 other Cardiomyopathy trials with a reported enrollment target (69% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02641145, a NA study of Cardiomyopathy and Amyloidosis, Primary, is actively recruiting participants, sponsored by Brigham and Women's Hospital.
- RECRUITING
- Registry status
- NA
- Development phase
- 171 participants
- Enrollment target
- 1
- Study location
Study Summary
Cardiac amyloidosis is a major cause of early treatment-related death and poor overall survival in individuals with systemic light chain amyloidosis. This project will develop a novel approach to visualize cardiac amyloid deposits using advanced imaging methods. The long-term goal of this work is to identify the mechanisms of cardiac dysfunction, in order to guide the development of novel life-saving treatments.
Primary Outcome
quantitative measure of F-18 florbetapir uptake by the heart muscle
Conditions Studied
Interventions
- RADIATION F-18 florbetapir/C-11 acetate PET
- DEVICE MRI
- RADIATION N-13 ammonia PET
Study Locations (1)
Massachusetts
- Brigham and Womens' Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 171 participants |
| Start Date | 2016-04-01 |
| Est. Completion | 2028-12-31 |
| Phase | NA |
What NCT02641145 shows while recruiting
NCT02641145 is an interventional study that assigns participants to a tested intervention. The registered 171 participants enrollment target is mid-sized for trials with a published cap, below the 550-participant average among 25 other Cardiomyopathy trials with a reported enrollment target (69% lower).
The record links to 2 conditions, with Cardiomyopathy appearing as the primary indexed condition, and to 3 interventions - of which F-18 florbetapir/C-11 acetate PET is the first listed.
NCT02641145 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT02641145 about?
NCT02641145 is a clinical study titled "Molecular Imaging of Primary Amyloid Cardiomyopathy". Cardiac amyloidosis is a major cause of early treatment-related death and poor overall survival in individuals with systemic light chain amyloidosis. This project will develop a novel approach to visualize cardiac amyloid deposits using advanced imaging methods. The long-term goal of this work is to...
What is the current status of trial NCT02641145?
This trial is currently recruiting. It is a NA study. The enrollment target is 171 participants. The study started on 2016-04-01. Estimated completion is 2028-12-31.
What conditions does trial NCT02641145 study?
This clinical trial studies the following conditions: Cardiomyopathy, Amyloidosis, Primary.
What interventions are being tested in trial NCT02641145?
The interventions under investigation include: F-18 florbetapir/C-11 acetate PET (RADIATION), MRI (DEVICE), N-13 ammonia PET (RADIATION).
Who is sponsoring clinical trial NCT02641145?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02641145 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cardiomyopathy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02641145's enrollment target sits among peer trials
171 12th of 25 higher than 14 of 25 other Cardiomyopathy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cardiomyopathy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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