Brigham and Women's Hospital
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Brigham and Women's Hospital sits in the top decile of US sponsors by registered trial count (#35 of 15,742 sponsors by registered trial count).
Brigham and Women's Hospital: 937 sponsored US clinical trials, 145 recruiting.
Brigham and Women's Hospital sponsors 937 registered US clinical trials on ClinicalTrials.gov, 145 of them currently recruiting, and 608 completed. 124 of these trials are in Phase 3-4 (later-stage) and 197 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Type 2 Diabetes, with 13 trials.
Top-decile sponsor footprint
Brigham and Women's Hospital ranks in the top decile of sponsors by registered trial count (#35 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
608 of 677 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (89.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
937 total, page 10 of 19
A Novel Pharmacological Therapy for Obstructive Sleep Apnea
NCT03919955
Replication of the LEAD-2 Diabetes Trial in Healthcare Claims Data
NCT05162183
Multimodality Intervention for Function and Metabolism in SCI
NCT03576001
Skilled Nursing Facility at Home: A Pilot
NCT04048590
Remote Physician Care for Home Hospital Patients
NCT04080570
The Impact of a Newborn Behavioral Intervention on the Mental Health of Mothers With Late Pre-Term Infants
NCT03836430
Replication of the EMPAREG Diabetes Trial in Healthcare Claims
NCT04215536
Replication of the DECLARE Diabetes Trial in Healthcare Claims
NCT04215523
The Provider Awareness and Cultural Dexterity Toolkit for Surgeons Trial
NCT03576495
Improving Safety of Diagnosis and Therapy in the Inpatient Setting
NCT04393909
Addressing Disparities in Lupus Care Through an Integrated Care Management Program
NCT03915652
Development of Ingestible Biosensors to Enhance PrEP Adherence in Substance Users (PrEPSteps)
NCT03512418
The Impact of Music on Nociceptive Processing
NCT04087564
Tranexamic Acid Pharmacokinetics During Postpartum Hemorrhage
NCT03863964
Reducing Structural Inequities in Heart Failure Management: An Approach to Improve the Quality of Heart Failure Care on the General Medicine Service: Longitudinal Equity Action Plan (LEAP)
NCT03942978
Healthy Sleep for Children With Down Syndrome
NCT03922165
The Impact of Low Flow Nocturnal Oxygen Therapy on Hospital Admissions and Mortality in Patients With Heart Failure and Central Sleep Apnea
NCT03745898
Respiratory-Gated Vagal Nerve Stimulation for Chronic Pain
NCT04053127
Second-Line Uterotonics in Postpartum Hemorrhage: A Randomized Clinical Trial
NCT03584854
Computerized Decision Support to Increase Detection of Chronic Thromboembolic Pulmonary Hypertension in Patients With Prior Pulmonary Embolism
NCT03729544
24 Month Open Label Study of the Tolerability and Efficacy of Inotersen in TTR Amyloid Cardiomyopathy Patients
NCT03702829
Magnesium Supplementation and Blood Pressure Reduction
NCT03688503
Initiating Substance Use Disorder Treatment for Hospitalized Opioid Use Disorder Patients.
NCT03212794
Efficacy of the Quell Wearable Device for Fibromyalgia
NCT03714425
Mineralocorticoid Receptor (MR) Antagonist (Eplerenone) vs Amlodipine and STRIATIN
NCT03683069
Combination Pharmacological Interventions for Multiple Mechanisms of Obstructive Sleep Apnea
NCT03892772
Efficacy and Safety of 0.25% Timolol Gel in Enhancing Full Thickness Skin Grafts Healing and Cosmetic Outcomes
NCT03579160
Length of Cook Catheter Placement and Induction of Labor
NCT04233008
Dietary Restriction in Vascular Surgery
NCT04013412
Pharmacological Intervention for Symptomatic Snoring
NCT03720353
Role of Dietary Habits in Efficacy of Bariatric Surgery - Study A
NCT03470558
Evaluation of Open-Label Conditioned Placebo Analgesia for Postoperative Opioid Reduction Following Spinal Fusion
NCT04574388
Feasibility of a Yoga- and Mindfulness-Based Intervention for Resident Physicians
NCT03687450
Pharmacological Activation of HMN for OSA
NCT03640052
Image-guided Lymphadanectomy in AMIGO
NCT03283423
Feasibility and Acceptability of Digital Pills to Monitor PrEP Adherence in MSM With Substance Use
NCT03842436
Ferumoxytol as a Contrast Agent for Pulmonary Magnetic Resonance Angiography
NCT03173066
Effects of Biktarvy on CFR in Stable HIV Patients
NCT03656783
A Proof-of-Concept Trial of a Positive Psychology Intervention for Allogeneic Stem Cell Transplant Patients
NCT03654404
Network Modulation in Alzheimer's Disease
NCT04045990
Replication of the GRADE Diabetes Trial in Healthcare Claims Data
NCT05099198
PREventing Adverse Events Post-Discharge Through Proactive Identification, Multidisciplinary Communication, and Technology
NCT05232656
Efficacy and Safety of 0.25% Timolol Gel in Healing Surgical Open Wounds
NCT03452072
Effect of Dupilumab on Sleep Apnea in Patients With Rhinosinusitis
NCT03675022
Entrainment-Based Mechanical Ventilation
NCT03512067
Pro-Resolving Mediators in Acute Inflammation in Humans
NCT04308889
Sulfasalazine for the Treatment of Primary Sclerosing Cholangitis
NCT03561584
The Impact of Music Therapy on Nociceptive Processing
NCT03692247
VITamin D and OmegA-3 TriaL (VITAL): Fractures, Vitamin D and Genetic Markers
NCT01704859
Electronic Alerts for Stroke Prevention in Atrial Fibrillation
NCT02958943
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 90 |
| Phase 2 | 107 |
| Phase 3 | 47 |
| Phase 4 | 77 |
Therapeutic Areas
What is open in the Brigham and Women's Hospital pipeline
145 recruiting of 937 indexed (15% open); 608 completed (65%).
Phase mix: 124 late (III/IV) vs 197 early (I/II) (early-phase heavy).
Top condition: Type 2 Diabetes (13 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Brigham and Women's Hospital: open-pipeline peers nationwide
Peers matched on 937 registered trials and 15% open enrollment, not the therapeutic-area sidebar.
Brigham and Women's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 937 trials (± recruiting share)
- Columbia University · 958 trials · 18% recruiting
- Hoffmann-La Roche · 909 trials · 8% recruiting
- University of Minnesota · 966 trials · 19% recruiting
- University of California, Los Angeles · 897 trials · 18% recruiting
Sponsors near 15% open enrollment (± trial volume)
- Incyte Corporation · 15% recruiting · 239 trials
- Northwestern University · 15% recruiting · 1,209 trials
- Nationwide Children's Hospital · 15% recruiting · 188 trials
- University of Michigan Rogel Cancer Center · 15% recruiting · 292 trials
Related
What to do with this Brigham and Women's Hospital page
937 registered trials is a research-attention snapshot, not an endorsement of Brigham and Women's Hospital or any single study.
- 145 of Brigham and Women's Hospital's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Type 2 Diabetes is the condition Brigham and Women's Hospital studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Type 2 Diabetes trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Brigham and Women's Hospital pipeline card: 937 registered trials from official public datasets.Report a data error.