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NCT03892772 · ClinicalTrials.gov registry record · Phase 1
Combination Pharmacological Interventions for Multiple Mechanisms of Obstructive Sleep Apnea
A Phase 1 study, sponsored by Brigham and Women's Hospital.
- Completed
- Registry status
- Phase 1
- Development phase
- 23
- Enrollment target
NCT03892772 is a Phase 1 study that has completed, run by Brigham and Women's Hospital. The registered enrollment target is 23 participants.
The verdict
NCT03892772, a Phase 1 study, has completed, sponsored by Brigham and Women's Hospital.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 23 participants
- Enrollment target
Study Summary
Currently, there is no pharmacological intervention for OSA that targets multiple pathophysiological deficits in combination. Here the investigators study the effect on sleep apnea severity of combinations of pharmacological agents that stimulate the pharyngeal muscles, stabilize ventilatory control, and increase the arousal threshold.
Interventions
- DRUG placebo
- DRUG SAS0421a
- DRUG SAS0421b
- DRUG SAS0421c
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 23 participants |
| Start Date | 2019-01-14 |
| Est. Completion | 2021-07-03 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03892772
The ClinicalTrials.gov registry entry for NCT03892772 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 23 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Brigham and Women's Hospital, which has 937 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 4 interventions - of which placebo is the first listed.
NCT03892772 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03892772 about?
NCT03892772 is a clinical study titled "Combination Pharmacological Interventions for Multiple Mechanisms of Obstructive Sleep Apnea". Currently, there is no pharmacological intervention for OSA that targets multiple pathophysiological deficits in combination. Here the investigators study the effect on sleep apnea severity of combinations of pharmacological agents that stimulate the pharyngeal muscles, stabilize ventilatory control...
What is the current status of trial NCT03892772?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 23 participants. The study started on 2019-01-14. Estimated completion is 2021-07-03.
What interventions are being tested in trial NCT03892772?
The interventions under investigation include: placebo (DRUG), SAS0421a (DRUG), SAS0421b (DRUG), SAS0421c (DRUG).
Who is sponsoring clinical trial NCT03892772?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
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