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COMPLETED Phase 2

Efficacy and Safety of 0.25% Timolol Gel in Healing Surgical Open Wounds

NCT03452072 · View on ClinicalTrials.gov ↗

Study Summary

The use of topical beta-blockers, such as 0.25% timolol, in promoting wound healing is currently emerging in the academic literature. The investigators will enroll 114 patients who have their skin cancer surgically removed resulting in open surgical wounds less or equal to 1.5 cm. The objective of this randomized safety study is to determine the safety and efficacy of 0.25% timolol in promoting wound healing in open surgical wounds less or equal to 1.5 cm.

Interventions

  • DRUG 0.25% Timolol gel with paraffin gauze dressings
  • OTHER Vaseline dressing

Study Locations (1)

Massachusetts

  • Mohs and Dermatologic Surgery Center, Brigham and Women's Hospital — Boston

Trial Details

FieldValue
Enrollment Target 88 participants
Start Date 2018-08-20
Est. Completion 2021-06-30
Phase Phase 2

Sponsor

Brigham and Women's Hospital

929 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT03452072

The ClinicalTrials.gov registry entry for NCT03452072 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 88 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Brigham and Women's Hospital, which has 929 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 4 conditions, with Wound Heal appearing as the primary indexed condition, and to 2 interventions — of which 0.25% Timolol gel with paraffin gauze dressings is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT03452072 reports 1 study location spanning 1 distinct geographic area — top geographies include Massachusetts. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT03452072 about?

NCT03452072 is a clinical study titled "Efficacy and Safety of 0.25% Timolol Gel in Healing Surgical Open Wounds". The use of topical beta-blockers, such as 0.25% timolol, in promoting wound healing is currently emerging in the academic literature. The investigators will enroll 114 patients who have their skin cancer surgically removed resulting in open surgical wounds less or equal to 1.5 cm. The objective of t...

What is the current status of trial NCT03452072?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 88 participants. The study started on 2018-08-20. Estimated completion is 2021-06-30.

What conditions does trial NCT03452072 study?

This clinical trial studies the following conditions: Wound Heal, Surgical Wound, Wound of Skin, Wound Open. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT03452072?

The interventions under investigation include: 0.25% Timolol gel with paraffin gauze dressings (DRUG), Vaseline dressing (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT03452072?

This trial is sponsored by Brigham and Women's Hospital, which has 929 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT03452072 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial