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NCT03584854 · ClinicalTrials.gov registry record · Phase 4
Second-Line Uterotonics in Postpartum Hemorrhage: A Randomized Clinical Trial
A Phase 4 study, sponsored by Brigham and Women's Hospital.
- Completed
- Registry status
- Phase 4
- Development phase
- 100
- Enrollment target
NCT03584854: Completed Phase 4 study, sponsored by Brigham and Women's Hospital.
NCT03584854 is a Phase 4 study that has completed, run by Brigham and Women's Hospital. The registered enrollment target is 100 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (81% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03584854, a Phase 4 study, has completed, sponsored by Brigham and Women's Hospital.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 100 participants
- Enrollment target
Study Summary
The aim of this study is to evaluate in a randomized fashion the comparative efficacy of two second-line medications, methylergonovine and carboprost for treating atonic postpartum hemorrhage (PPH). The investigators hypothesize that administration of methylergonovine will produce superior uterine tone to carboprost in atonic PPH.
Primary Outcome
Uterine contractile tone will be measured on a 0-10 score as assessed by the obstetrician; 0 is 'no tone', 10 is 'perfect tone' or 'excellent tone'.
Interventions
- DRUG 15-methyl prostaglandin F2α
- DRUG Methylergonovine Maleate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2019-03-01 |
| Est. Completion | 2022-06-15 |
| Phase | Phase 4 |
What the finished NCT03584854 record still lists
NCT03584854 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (81% lower).
The record links to 0 conditions, and to 2 interventions - of which 15-methyl prostaglandin F2α is the first listed.
NCT03584854 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03584854 about?
NCT03584854 is a clinical study titled "Second-Line Uterotonics in Postpartum Hemorrhage: A Randomized Clinical Trial". The aim of this study is to evaluate in a randomized fashion the comparative efficacy of two second-line medications, methylergonovine and carboprost for treating atonic postpartum hemorrhage (PPH). The investigators hypothesize that administration of methylergonovine will produce superior uterine t...
What is the current status of trial NCT03584854?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 100 participants. The study started on 2019-03-01. Estimated completion is 2022-06-15.
What interventions are being tested in trial NCT03584854?
The interventions under investigation include: 15-methyl prostaglandin F2α (DRUG), Methylergonovine Maleate (DRUG).
Who is sponsoring clinical trial NCT03584854?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03584854's enrollment target sits among peer trials
100 770th of 2000 higher than 1,148 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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