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NCT03729544 · ClinicalTrials.gov registry record · NA

Computerized Decision Support to Increase Detection of Chronic Thromboembolic Pulmonary Hypertension in Patients With Prior Pulmonary Embolism

A NA study, sponsored by Brigham and Women's Hospital.

Completed
Registry status
NA
Development phase
400
Enrollment target

NCT03729544: Completed NA study, sponsored by Brigham and Women's Hospital.

NCT03729544 is a NA study that has completed, run by Brigham and Women's Hospital. The registered enrollment target is 400 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (72% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03729544, a NA study, has completed, sponsored by Brigham and Women's Hospital.

COMPLETED
Registry status
NA
Development phase
400 participants
Enrollment target

Study Summary

To address the knowledge gap that exists among providers resulting in underdiagnosis of chronic thromboembolic pulmonary hypertension (CTEPH), the investigators have devised this 400-patient single-center Quality Improvement Initiative in the form of a randomized controlled trial of an EPIC Best Practice Advisory (BPA) on-screen alert versus no notification to increase echocardiographic screening for CTEPH and the diagnosis of CTEPH in patients with prior pulmonary embolism (PE) and symptoms/signs suggestive of pulmonary hypertension or recent pulmonary testing suggesting unexplained respiratory symptoms at 3 months. Aim #1: To determine the impact of a Best Practice Advisory (BPA), using the EPIC Electronic Health Record computerized decision support (CDS) software, on echocardiographic screening for CTEPH in patient with prior PE and symptoms/signs suggestive of pulmonary hypertension or recent pulmonary testing suggesting unexplained respiratory symptoms. Aim #2: To determine the impact of an EPIC BPA on the diagnosis of CTEPH in patient with prior PE and symptoms/signs suggestive of pulmonary hypertension or recent pulmonary testing suggesting unexplained respiratory symptoms.

Primary Outcome

Investigators will review the Provider Order Entry and cardiology test results sections of the Electronic Health Record (EPIC) to make this determination.

Interventions

  • BEHAVIORAL On-screen computerized decision support alert

Trial Details

FieldValue
Enrollment Target 400 participants
Start Date 2019-03-01
Est. Completion 2025-12-30
Phase NA
Brigham and Women's Hospital

937 total trials

What the finished NCT03729544 record still lists

NCT03729544 is an interventional study that assigns participants to a tested intervention. The registered 400 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (72% lower).

The record links to 0 conditions, and to 1 intervention - of which On-screen computerized decision support alert is the first listed.

NCT03729544 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03729544 about?

NCT03729544 is a clinical study titled "Computerized Decision Support to Increase Detection of Chronic Thromboembolic Pulmonary Hypertension in Patients With Prior Pulmonary Embolism". To address the knowledge gap that exists among providers resulting in underdiagnosis of chronic thromboembolic pulmonary hypertension (CTEPH), the investigators have devised this 400-patient single-center Quality Improvement Initiative in the form of a randomized controlled trial of an EPIC Best Pra...

What is the current status of trial NCT03729544?

This trial is currently completed. It is a NA study. The enrollment target is 400 participants. The study started on 2019-03-01. Estimated completion is 2025-12-30.

What interventions are being tested in trial NCT03729544?

The interventions under investigation include: On-screen computerized decision support alert (BEHAVIORAL).

Who is sponsoring clinical trial NCT03729544?

This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03729544's enrollment target sits among peer trials

400 246th of 2000 higher than 1,734 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03729544, the US trial registry maintained by the National Library of Medicine. NCT03729544 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.