Brigham and Women's Hospital

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Brigham and Women's Hospital sits in the top decile of US sponsors by registered trial count (#35 of 15,742 sponsors by registered trial count).

937 total trials 145 currently recruiting 608 completed early-phase tilt top decile by trial count

Brigham and Women's Hospital: 937 sponsored US clinical trials, 145 recruiting.

Brigham and Women's Hospital sponsors 937 registered US clinical trials on ClinicalTrials.gov, 145 of them currently recruiting, and 608 completed. 124 of these trials are in Phase 3-4 (later-stage) and 197 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Type 2 Diabetes, with 13 trials.

Top-decile sponsor footprint

Brigham and Women's Hospital ranks in the top decile of sponsors by registered trial count (#35 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 64/100

608 of 677 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (89.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

937 total, page 9 of 19

COMPLETED

Replication of the VERO Osteoporosis Trial in Healthcare Claims Data

NCT04879420

COMPLETED NA

ACT for High Frequency Migraine; A Virtual Mindfulness Intervention

NCT05003362

COMPLETED NA

Optimizing Electronic Health Record Prompts With Behavioral Economics to Improve Prescribing for Older Adults

NCT04284553

COMPLETED

Replication of the EINSTEIN-PE Anticoagulant Trial in Healthcare Claims Data

NCT04879407

COMPLETED

Replication of the ISAR-REACT 5 Antiplatelet Trial in Healthcare Claims Data

NCT05086081

COMPLETED Phase 1

Detecting Compartment Syndrome Pain in the Presence of Regional Anesthesia in Healthy Volunteers

NCT04113954

COMPLETED

Replication of the INSPIRE Trial in Healthcare Claims Data

NCT05179512

COMPLETED

Replication of the AMPLIFY Anticoagulant Trial in Healthcare Claims Data

NCT04736719

COMPLETED

Replication of the HORIZON Pivotal Fracture Trial in Healthcare Claims Data

NCT04736693

COMPLETED

Replication of the RECORD1 Anticoagulant Trial in Healthcare Claims Data

NCT05083455

COMPLETED

Replication of the EINSTEIN-DVT Anticoagulant Trial in Healthcare Claims Data

NCT04736420

COMPLETED

Replication of the RECOVER-II Anticoagulant Trial in Healthcare Claims Data

NCT04735523

COMPLETED

Replication of the POET-COPD Trial in Healthcare Claims Data

NCT05083429

COMPLETED

Replication of the PARADIGM-HF Heart Failure Trial in Healthcare Claims Data.

NCT04736433

COMPLETED Phase 3

9-month Study to Assess the Efficacy of Ofatumumab on Microglia in Patients With Relapsing Forms of Multiple Sclerosis

NCT04510220

COMPLETED NA

Phenotyping Mechanistic Pathways for Adverse Health Outcomes in Sleep Apnea

NCT04575740

COMPLETED Phase 2

Calcium Channel Blockade in Primary Aldosteronism

NCT04179019

COMPLETED

Replication of the ARISTOTLE Anticoagulant Trial in Healthcare Claims Data

NCT04593030

COMPLETED

Replication of the ROCKET-AF Anticoagulant Trial in Healthcare Claims Data

NCT04593056

COMPLETED NA

A Pilot Study Examining Diet in Primary Sclerosing Cholangitis

NCT04678219

TERMINATED NA

Sleep and Circadian Treatments for Shift Workers

NCT03813654

COMPLETED

Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) - Tocilizumab vs Abatacept

NCT04529863

COMPLETED

Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) - Tofacitinib vs Abatacept

NCT04529876

COMPLETED NA

Optimizing the Safety of Inter-Hospital Transfer

NCT05876429

COMPLETED

Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) - TNFi vs Abatacept

NCT04529902

COMPLETED NA

Operational Trial of Dayzz App

NCT04224285

COMPLETED Phase 2

Cannabidiol Use to Reduce Cravings in Individuals With Opioid Use Disorder on Buprenorphine

NCT04192370

COMPLETED NA

Weight Loss Before Total Joint Arthroplasty Using A Remote Dietitian and Mobile App

NCT04330391

COMPLETED NA

Integrating Chiropractic Care and Mind-Body Training for the Treatment of Nonspecific Chronic Neck Pain

NCT06523036

TERMINATED Phase 3

Evaluation of SARS-CoV-2 (COVID-19) Antibody-containing Plasma thErapy

NCT04361253

COMPLETED

Study of the Treatment and Outcomes in Critically Ill Patients With COVID-19

NCT04343898

COMPLETED

COVID-19 Registry to Assess Frequency, Risk Factors, Management, and Outcomes of Arterial and Venous Thromboembolic Complications

NCT04535128

COMPLETED Phase 1

Role of Microglial Activation and Norepinephrine Transporter Abnormalities in Pathogenesis of MS-related Fatigue

NCT04144257

COMPLETED

Acceptability of Telehealth Triage Using Robotic Systems in COVID-19

NCT04452695

COMPLETED

COVID-19 Risk Stratification

NCT04339387

COMPLETED NA

A Study of Bedside Versus Hallway Rounding

NCT04754828

COMPLETED Phase 4

Comparing Nifedipine and Enalapril in Medical Resources Used in the Postpartum Period

NCT04236258

COMPLETED Phase 2

The Exercise Response to Pharmacologic Cholinergic Stimulation in Myalgic Encephalomyelitis / Chronic Fatigue Syndrome

NCT03674541

COMPLETED NA

Sleep Bootcamp: A Pilot Tele-Sleep Program for Former National Football League (NFL) Players

NCT04159233

COMPLETED NA

Project 3 Example: Human-AI Collaboration Tester (HAICT) Exp. 7

NCT05272189

COMPLETED Phase 2

ICON-2: FMT and Bezlotoxumab Compared to FMT and Placebo for Patients With IBD and CDI

NCT03829475

COMPLETED

Replication of the RELY Anticoagulant Trial in Healthcare Claims Data

NCT04593043

COMPLETED

Quantitative 3-Dimensional Chest CT Vascular Reconstruction Before and After Anticoagulation for Pulmonary Embolism

NCT04113421

TERMINATED NA

Even-Up to Minimize Secondary Site Pain For Ankle Fracture

NCT04164563

TERMINATED NA

Control:Diabetes Pilot Study I

NCT04158921

COMPLETED Phase 4

Inflammation in Women With Urgency Urinary Incontinence Treated With Anticholinergics

NCT04090190

COMPLETED NA

The Functional Neuroanatomy of the Human Physiological Stress Response

NCT03867344

COMPLETED

Replication of the PLATO Antiplatelet Trial in Healthcare Claims Data

NCT04237935

COMPLETED

Replication of the TRITON-TIMI Antiplatelet Trial in Healthcare Claims Data

NCT04237922

COMPLETED

Prediction of the PRONOUNCE Prostate Cancer Trial in Healthcare Claims Data

NCT04897958

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Phase Distribution

PhaseTrial count
Phase 1 90
Phase 2 107
Phase 3 47
Phase 4 77

What is open in the Brigham and Women's Hospital pipeline

145 recruiting of 937 indexed (15% open); 608 completed (65%).

Phase mix: 124 late (III/IV) vs 197 early (I/II) (early-phase heavy).

Top condition: Type 2 Diabetes (13 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Brigham and Women's Hospital: open-pipeline peers nationwide

Peers matched on 937 registered trials and 15% open enrollment, not the therapeutic-area sidebar.

Brigham and Women's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 5%10%15%20% Total trials Recruiting share Brigham and Women's HospitalColumbia UniversityHoffmann-La RocheUniversity of MinnesotaUniversity of California, Los AngelesIncyte CorporationNorthwestern UniversityNationwide Children's HospitalUniversity of Michigan Rogel Cancer Center
Brigham and Women's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Brigham and Women's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 937 trials (± recruiting share)

Sponsors near 15% open enrollment (± trial volume)

What to do with this Brigham and Women's Hospital page

937 registered trials is a research-attention snapshot, not an endorsement of Brigham and Women's Hospital or any single study.

  • 145 of Brigham and Women's Hospital's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Type 2 Diabetes is the condition Brigham and Women's Hospital studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Type 2 Diabetes trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Brigham and Women's Hospital pipeline card: 937 registered trials from official public datasets.Report a data error.