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NCT03173066 · ClinicalTrials.gov registry record · Phase 1

Ferumoxytol as a Contrast Agent for Pulmonary Magnetic Resonance Angiography

A Phase 1 study, sponsored by Brigham and Women's Hospital.

Completed
Registry status
Phase 1
Development phase
1
Enrollment target

NCT03173066: Completed Phase 1 study, sponsored by Brigham and Women's Hospital.

NCT03173066 is a Phase 1 study that has completed, run by Brigham and Women's Hospital. The registered enrollment target is 1 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03173066, a Phase 1 study, has completed, sponsored by Brigham and Women's Hospital.

COMPLETED
Registry status
Phase 1
Development phase
1 participants
Enrollment target

Study Summary

This proposal is based on findings from our previous work involving ferumoxytol-enhanced cardiac magnetic resonance angiography. The resolution of the pulmonary vasculature based on our previous imaging protocol was exceptional (PMID: 26786296). In the Partners Healthcare System between January 1, 2014 and January 1, 2015 there were 541 patients evaluated in Partners Healthcare-affiliated hospitals with a diagnosis of pulmonary embolism and acute or chronic kidney disease at the same visit between 01/01/2014 and 01/01/2015. Ventilation perfusion scanning was performed in 201 patients during this same time interval. Up to 63% of these patients in one year did not receive the diagnostic test of choice.

Primary Outcome

Detection of pulmonary embolus with ferumoxytol-enhanced magnetic resonance angiography

Interventions

  • DRUG Ferumoxytol

Trial Details

FieldValue
Enrollment Target 1 participants
Start Date 2018-09-21
Est. Completion 2022-05-31
Phase Phase 1
Brigham and Women's Hospital

937 total trials

What the finished NCT03173066 record still lists

NCT03173066 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 1 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (98% lower).

The record links to 0 conditions, and to 1 intervention - of which Ferumoxytol is the first listed.

NCT03173066 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03173066 about?

NCT03173066 is a clinical study titled "Ferumoxytol as a Contrast Agent for Pulmonary Magnetic Resonance Angiography". This proposal is based on findings from our previous work involving ferumoxytol-enhanced cardiac magnetic resonance angiography. The resolution of the pulmonary vasculature based on our previous imaging protocol was exceptional (PMID: 26786296). In the Partners Healthcare System between January 1, 2...

What is the current status of trial NCT03173066?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 1 participants. The study started on 2018-09-21. Estimated completion is 2022-05-31.

What interventions are being tested in trial NCT03173066?

The interventions under investigation include: Ferumoxytol (DRUG).

Who is sponsoring clinical trial NCT03173066?

This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03173066's enrollment target sits among peer trials

1 2001st of 2000 the lowest of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03173066, the US trial registry maintained by the National Library of Medicine. NCT03173066 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.