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NCT04574388 · ClinicalTrials.gov registry record · NA
Evaluation of Open-Label Conditioned Placebo Analgesia for Postoperative Opioid Reduction Following Spinal Fusion
A NA study of Spine Surgery, sponsored by Brigham and Women's Hospital.
- Completed
- Registry status
- NA
- Development phase
- 51
- Enrollment target
- 1
- Study location
NCT04574388: Completed NA study of Spine Surgery, sponsored by Brigham and Women's Hospital.
NCT04574388 is a NA study of Spine Surgery that has completed, run by Brigham and Women's Hospital. The registered enrollment target is 51 participants, below the 279-participant average among 6 other Spine Surgery trials with a reported enrollment target (82% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04574388, a NA study of Spine Surgery, has completed, sponsored by Brigham and Women's Hospital.
- COMPLETED
- Registry status
- NA
- Development phase
- 51 participants
- Enrollment target
- 1
- Study location
Study Summary
This research aims to understand the impact of conditioned open label placebo (COLP) on opioid consumption and pain after surgery. The hypothesis being tested is that by pairing a non-deceptive placebo pill with regularly prescribed pain killers after surgery, will allow reduction in opioids taken while maintaining the same level of analgesia.
Primary Outcome
daily report of post-discharge opioid use in sub-acute postoperative period, converted into morphine milligram equivalents
Conditions Studied
Interventions
- OTHER open label placebo
Study Locations (1)
Massachusetts
- Brigham and Women's Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 51 participants |
| Start Date | 2018-11-30 |
| Est. Completion | 2020-03-10 |
| Phase | NA |
What the finished NCT04574388 record still lists
NCT04574388 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 51 participants, a relatively small participant target, below the 279-participant average among 6 other Spine Surgery trials with a reported enrollment target (82% lower).
The record links to 1 condition, with Spine Surgery appearing as the primary indexed condition, and to 1 intervention - of which open label placebo is the first listed.
NCT04574388 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT04574388 about?
NCT04574388 is a clinical study titled "Evaluation of Open-Label Conditioned Placebo Analgesia for Postoperative Opioid Reduction Following Spinal Fusion". This research aims to understand the impact of conditioned open label placebo (COLP) on opioid consumption and pain after surgery. The hypothesis being tested is that by pairing a non-deceptive placebo pill with regularly prescribed pain killers after surgery, will allow reduction in opioids taken w...
What is the current status of trial NCT04574388?
This trial is currently completed. It is a NA study. The enrollment target is 51 participants. The study started on 2018-11-30. Estimated completion is 2020-03-10.
What conditions does trial NCT04574388 study?
This clinical trial studies the following conditions: Spine Surgery.
What interventions are being tested in trial NCT04574388?
The interventions under investigation include: open label placebo (OTHER).
Who is sponsoring clinical trial NCT04574388?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04574388 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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