Brigham and Women's Hospital

Compiled by PlainTrial · August 8, 2026

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Brigham and Women's Hospital sits in the top decile of US sponsors by registered trial count (#35 of 15,742 sponsors by registered trial count).

937 total trials 145 currently recruiting 608 completed early-phase tilt top decile by trial count

Brigham and Women's Hospital: 937 sponsored US clinical trials, 145 recruiting.

Brigham and Women's Hospital sponsors 937 registered US clinical trials on ClinicalTrials.gov, 145 of them currently recruiting, and 608 completed. 124 of these trials are in Phase 3-4 (later-stage) and 197 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Type 2 Diabetes, with 13 trials.

Brigham and Women's Hospital ranks in the top decile of sponsors by registered trial count (#35 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 64/100

608 of 677 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (89.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

937 total, page 11 of 19

COMPLETED Phase 2

Contrast Enhanced Ultrasonography to Detect Human Renal Transplant Rejection

NCT02733029

COMPLETED Phase 4

Gabapentin Regimens and Their Effects on Opioid Consumption

NCT03334903

COMPLETED Phase 1

Angiogenic Imaging in Pulmonary Arterial Hypertension

NCT03166306

COMPLETED Phase 2

Therapeutic Control of Aspirin-Exacerbated Respiratory Disease With Ifetroban

NCT03326063

TERMINATED NA

Virtual Visits at Brigham and Women's Hospital

NCT03592355

Brigham and Women's Hospital

Top-decile sponsor footprint

Open and recent trials

Contrast Enhanced Ultrasonography to Detect Human Renal Transplant Rejection

Gabapentin Regimens and Their Effects on Opioid Consumption

Angiogenic Imaging in Pulmonary Arterial Hypertension

Therapeutic Control of Aspirin-Exacerbated Respiratory Disease With Ifetroban

Virtual Visits at Brigham and Women's Hospital

Prediction of Outcomes Following Total Knee Replacement- Pilot

A Positive Psychology Intervention for Patients With Multiple Sclerosis

Interaction of Melatonin With MTNR1B Genotype on Glucose Control - Study 2

Potatoes, Hypertension RIsk and Endothelial Function Study

Comparing Different Types of Physical Therapy for Treating People With a Meniscal Tear and Osteoarthritis

Brief Title: Project 4 Example: Mixed Hybrid Checklist

Fetal Pillow Randomized Controlled Trial

Adapting Sleep and Yoga Interventions for Maximal Effectiveness in Low Income Populations

DAW1033D in Obstructive Sleep Apnea

Supraclavicular Block vs Retroclavicular Block: Incidence of Phrenic Nerve Paralysis

Patient Empowered Strategy to Reduce Asthma Morbidity in Highly Impacted Populations; PeRson EmPowered Asthma RElief

Novel Strategies to Improve Immunomodulation and Non-invasive Clinical Monitoring in VCA

Excess Opioid Disposal Following Orthopedic Foot and Ankle Surgery

Hypoglycemia and Autonomic Nervous System Function- B2

Replication of the LEADER Diabetes Trial in Healthcare Claims

Replication of the ONTARGET Antihypertensive Trial in Healthcare Claims Data

Replication of the CARMELINA Diabetes Trial in Healthcare Claims

Replication of the TRANSCEND Antihypertensive Trial in Healthcare Claims Data

Replication of the SAVOR-TIMI Diabetes Trial in Healthcare Claims

Replication of the TECOS Diabetes Trial in Healthcare Claims

Replication of the CANVAS Diabetes Trial in Healthcare Claims

DAW1033B2 in Obstructive Sleep Apnea

Somatotopic Configuration of Distal Residual Limb Tissues in Lower Extremity Amputations

Short-Term Endogenous Hydrogen Sulfide Upregulation

Combined Upper-airway and Breathing Control Therapies for Obstructive Sleep Apnea

Rotational Thromboelastometry for the Transfusion Management of Postpartum Hemorrhage After Vaginal or Cesarean Delivery

Safety and Cardiovascular Efficacy of Hydralazine and Isosorbide Dinitrate in Dialysis-Dependent ESRD

Enabling Personalized Medicine Through Exome Sequencing in the U.S. Air Force

Home-Based Exercise Program For Recovery After Transcatheter Aortic Valve Replacement

Motivational Interview Intervention to Help Patients Formulate Their Goals for Medical Care in the Emergency Department

The ICON Study: Outcomes After FMT for Patients With IBD and CDI

Menopausal Sleep Fragmentation and Body Fat Gain

Measurement of Renal Functional Reserve

Validation of Novel Predictive Score for Patients With Spinal Metastases

Acute Kidney Injury Standardized Clinical Assessment and Management Plan for Renal Replacement Initiation

Immune Profiling During Ocrelizumab Treatment in Multiple Sclerosis

Post-Acute Physician Home Visit Program

Pediatric Adenotonsillectomy Trial for Snoring

Hospital-Level Care at Home for Acutely Ill Adults

Spine Pain INtervention to Enhance Care Quality And Reduce Expenditure

Prediction of 30-Day Readmission Using Machine Learning

Efficacy of Suvorexant in the Treatment of Hot Flash-associated Insomnia

Determine the Most Effective Intervention for Hemorrhage Control Readiness for Laypersons: The PATTS Trial

Informed Implementation of Breast Density Reporting

Preoperative Cognitive Screening in Older Spinal Surgical Patients

Phase Distribution

Therapeutic Areas

What is open in the Brigham and Women's Hospital pipeline

Brigham and Women's Hospital: open-pipeline peers nationwide

Sponsors near 937 trials (± recruiting share)

Sponsors near 15% open enrollment (± trial volume)

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