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NCT00499317 · ClinicalTrials.gov registry record

Genetic Study of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)

A clinical trial of Interstitial Cystitis and Chronic Pelvic Pain Syndrome (CPPS), sponsored by Boston Children's Hospital.

Recruiting
Registry status
500
Enrollment target
1
Study location

NCT00499317: Recruiting study of Interstitial Cystitis and Chronic Pelvic Pain Syndrome (CPPS), sponsored by Boston Children's Hospital.

NCT00499317 is a study of Interstitial Cystitis and Chronic Pelvic Pain Syndrome (CPPS) that is actively recruiting participants, run by Boston Children's Hospital. The registered enrollment target is 500 participants, above the 343-participant average among 26 other Interstitial Cystitis trials with a reported enrollment target (46% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00499317, a study of Interstitial Cystitis and Chronic Pelvic Pain Syndrome (CPPS), is actively recruiting participants, sponsored by Boston Children's Hospital.

RECRUITING
Registry status
500 participants
Enrollment target
1
Study location

Study Summary

Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) is a condition with several causes of which some remain unknown. It is believed that some types of CP may be genetic or passed down (inherited) from one generation to the next. In this study, we are collecting genetic material and medical information to try to determine if genetic factors play a role in CP/CPPS. We will be collecting DNA (from Blood/Saliva sample) and urine from each participant. Bladder tissue from affected individuals will also be collected. Individuals and families with CP/CPPS will be enrolled. Family members of an individual with CP/CPPS are eligible whether or not they also experience CP/CPPS symptoms.

Primary Outcome

DNA from blood/saliva and, when available, bladder or skin tissue will be analyzed using linkage analysis, whole exome/genome sequencing, and candidate gene approaches to identify candidate disease-causing variants associated with CP/CPPS, IC/BPS, PBS, or BFS. The measure will be summarized as the number of participants with candidate disease-causing variant(s), and when applicable, co-segregation of variants with affected status or symptoms.

Conditions Studied

Interstitial Cystitis Chronic Pelvic Pain Syndrome (CPPS) Painful Bladder Syndrome (PBS) Chronic Prostatitis (CP) Benign Frequency Syndrome (BFS)

Study Locations (1)

Massachusetts

  • Boston Children's Hospital (BCH) - Boston

Trial Details

FieldValue
Enrollment Target 500 participants
Start Date 2007-01-15
Est. Completion 2026-12-31
Boston Children's Hospital

462 total trials

What NCT00499317 shows while recruiting

NCT00499317 is an observational study that tracks outcomes without assigning an intervention. The registered 500 participants enrollment target is mid-sized for trials with a published cap, above the 343-participant average among 26 other Interstitial Cystitis trials with a reported enrollment target (46% higher).

The record links to 5 conditions, with Interstitial Cystitis appearing as the primary indexed condition, and to 0 interventions.

NCT00499317 reports a single indexed study location in Massachusetts.

Frequently Asked Questions

What is clinical trial NCT00499317 about?

NCT00499317 is a clinical study titled "Genetic Study of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)". Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) is a condition with several causes of which some remain unknown. It is believed that some types of CP may be genetic or passed down (inherited) from one generation to the next. In this study, we are collecting genetic material and medical i...

What is the current status of trial NCT00499317?

This trial is currently recruiting. The enrollment target is 500 participants. The study started on 2007-01-15. Estimated completion is 2026-12-31.

What conditions does trial NCT00499317 study?

This clinical trial studies the following conditions: Interstitial Cystitis, Chronic Pelvic Pain Syndrome (CPPS), Painful Bladder Syndrome (PBS), Chronic Prostatitis (CP), Benign Frequency Syndrome (BFS).

Who is sponsoring clinical trial NCT00499317?

This trial is sponsored by Boston Children's Hospital, which has 462 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00499317 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Interstitial Cystitis

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00499317's enrollment target sits among peer trials

500 5th of 26 higher than 22 of 26 other Interstitial Cystitis trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Interstitial Cystitis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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More recruiting context for NCT00499317

Source: ClinicalTrials.gov NCT00499317, the US trial registry maintained by the National Library of Medicine. NCT00499317 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.