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NCT02743845 · ClinicalTrials.gov registry record

Gene Discovery Core, The Manton Center

A clinical trial of Rare Disorders and Undiagnosed Conditions, sponsored by Boston Children's Hospital.

Recruiting
Registry status
10,000
Enrollment target
1
Study location

NCT02743845 is a study of Rare Disorders and Undiagnosed Conditions that is actively recruiting participants, run by Boston Children's Hospital. The registered enrollment target is 10,000 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT02743845, a study of Rare Disorders and Undiagnosed Conditions, is actively recruiting participants, sponsored by Boston Children's Hospital.

RECRUITING
Registry status
10,000 participants
Enrollment target
1
Study location

Study Summary

The Gene Discovery Core at The Manton Center for Orphan Disease Research based at Boston Children's Hospital studies families with rare, poorly understood or undiagnosed, but suspected genetic conditions. The primary goal of the research is to better understand the genes and proteins (gene products) involved in rare diseases. The researchers hope that our studies will allow for improved diagnosis and treatment of individuals with rare disease in the future. Individuals with any rare/undiagnosed condition are eligible to enroll. Enrollment includes: * Providing DNA and tissue samples (when available) * Access to participants' medical records * Access to genomic data (when available) Samples are used for genetic analysis (primarily exome and genome sequencing or reanalysis) to identify the genetic cause for the individual's illness. Individual research results are returned to families through their health care provider after confirmation in a clinical lab. If a cause is identified, that can be reported back to the family through their health care provider and the study's genetic counselor. When possible, the investigators also collect samples from parents and full-siblings as well as any other affected family members.

Study Locations (1)

Massachusetts

  • Boston Children's Hospital - Boston

Trial Details

FieldValue
Enrollment Target 10,000 participants
Start Date 2010-02
Est. Completion 2030-12

Sponsor

Boston Children's Hospital

462 total trials

What the Registry Record Tells You About NCT02743845

The ClinicalTrials.gov registry entry for NCT02743845 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 10,000 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Boston Children's Hospital, which has 462 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Rare Disorders appearing as the primary indexed condition, and to 0 interventions.

NCT02743845 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT02743845 about?

NCT02743845 is a clinical study titled "Gene Discovery Core, The Manton Center". The Gene Discovery Core at The Manton Center for Orphan Disease Research based at Boston Children's Hospital studies families with rare, poorly understood or undiagnosed, but suspected genetic conditions. The primary goal of the research is to better understand the genes and proteins (gene products)...

What is the current status of trial NCT02743845?

This trial is currently recruiting. The enrollment target is 10,000 participants. The study started on 2010-02. Estimated completion is 2030-12.

What conditions does trial NCT02743845 study?

This clinical trial studies the following conditions: Rare Disorders, Undiagnosed Conditions, Orphan Diseases.

Who is sponsoring clinical trial NCT02743845?

This trial is sponsored by Boston Children's Hospital, which has 462 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02743845 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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