Boston Children's Hospital

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Boston Children's Hospital sits in the top decile of US sponsors by registered trial count (#77 of 15,742 sponsors by registered trial count).

462 total trials 110 currently recruiting 268 completed early-phase tilt top decile by trial count

Boston Children's Hospital: 462 sponsored US clinical trials, 110 recruiting.

Boston Children's Hospital sponsors 462 registered US clinical trials on ClinicalTrials.gov, 110 of them currently recruiting, and 268 completed. 35 of these trials are in Phase 3-4 (later-stage) and 53 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Congenital Heart Disease, with 9 trials.

Top-decile sponsor footprint

Boston Children's Hospital ranks in the top decile of sponsors by registered trial count (#77 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 61/100

268 of 303 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.4%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

462 total, page 4 of 10

NOT YET RECRUITING

Pharmacokinetic and Pharmacodynamic Investigations of Fetal Anesthesia During Maternal Fetal Surgery

NCT07571811

NOT YET RECRUITING

The Association Between Tau & GFAP and Postoperative Neurological Impairment in Patients Undergoing Cardiac Surgery

NCT06899971

NOT YET RECRUITING NA

Exercise as Medicine for Pediatric Chronic Pain

NCT07182006

NOT YET RECRUITING

Evaluation of a Point-of-care Lateral Flow Assay in Glial Fibrillary Acidic Protein (GFAP) and D-dimer in Diagnosis of Large Vessel Occlusion Acute Ischemic Stroke in a Pediatric Hospital

NCT07474675

NOT YET RECRUITING Early Phase 1

Virtual Reality and Biofeedback for Adolescents With Chronic Dizziness

NCT07374640

NOT YET RECRUITING Phase 3

Optimal Timing of Ketamine Initiation for SCD Pain

NCT07450430

NOT YET RECRUITING Phase 1

Valproate for the Treatment of Residual Amblyopia

NCT07226141

NOT YET RECRUITING NA

Evaluation of a Supervised Clinical Feeding Intervention

NCT06892132

NOT YET RECRUITING

Impact of Stimulants and In-Scanner Motion on Attentive Task Performance in ADHD (ADHD_NFB)

NCT06779825

COMPLETED NA

A Trial to Determine People's Explicit vs. Implicit Preferences for Gender-inclusive Sexual and Reproductive Health Content

NCT07601581

COMPLETED NA

Bedtime Stories: A Sleep Health Education Program for Healthcare Providers

NCT06455579

COMPLETED Phase 4

Lidocaine Versus Bupivacaine in Orthognathic Surgery

NCT06450028

COMPLETED NA

Improving Social Relationships for Adolescents With Central Disorders of Hypersomnolence

NCT06251063

COMPLETED NA

An Innovative Taping Technique for Improved Intravenous (IV) Catheter Securement

NCT05948878

COMPLETED Phase 1

Biomarkers of ADHD Treatment Response

NCT05650775

COMPLETED NA

Improving Short Course Treatment for Common Pediatric Infections

NCT06087809

COMPLETED NA

Intervening in Food Insecurity to Reduce and Mitigate (InFoRM) Childhood Obesity

NCT05586269

TERMINATED Phase 2

Epinephrine in the Pediatric Intensive Care Unit: A Dose-Effect Trial

NCT05327556

COMPLETED

Assessing the Impact of Exercise Based Intensive Interdisciplinary Pain Treatment (IIPT) on Endogenous Pain Modulation in Youth With Chronic Pain Syndromes

NCT05491499

COMPLETED NA

Enhanced External Counterpulsation in Patients With Fontan Circulation

NCT04956952

TERMINATED Phase 2

Initial Pain Management in Pediatric Pancreatitis: Opioid vs. Non-Opioid

NCT04291599

COMPLETED NA

Cold Therapy for Pediatric Appendectomy

NCT04986397

COMPLETED NA

A Pilot Study of a Low Glycemic Load Diet in Adults With Cystic Fibrosis

NCT04519853

COMPLETED NA

Benign Paroxysmal Positional Vertigo (BPPV) Training for Sports Medicine Providers in a Pediatric Concussion Program

NCT03425786

COMPLETED Phase 4

Effect of Dexmedetomidine of Gastrointestinal Motility

NCT04798482

COMPLETED NA

A Single Blinded Randomized Controlled Trial Testing the Efficacy of a Pediatric Interactive Relational Agent vs. Standard Preoperative Education

NCT04586569

COMPLETED

Pediatric Teduglutide Registry

NCT04832087

COMPLETED NA

Validation of a Novel Non-invasive Continuous Blood Pressure Monitor in Children Ages 2- 17 Years-old

NCT04817137

COMPLETED Phase 1

Senicapoc and Dehydrated Stomatocytosis

NCT04372498

TERMINATED NA

Predicting Arrhythmogenic Risk in Congenital Heart Patients: the PRECISION Study

NCT04768634

COMPLETED NA

Pain in Fibrous Dysplasia

NCT04125862

COMPLETED NA

The Use of Mobile Health Technology and Behavioral Economics to Encourage Adherence in Adolescents

NCT04458766

COMPLETED

Society for Pediatric Anesthesia Improvement Network- Anterior Cruciate Ligament Reconstruction Outcomes Project

NCT04329117

COMPLETED

Qualitative Understanding of Experiences With the SIMPLIFY Trial

NCT04320381

COMPLETED

Wide Scale Monitoring for Acute Respiratory Infection Using a Mobile-Based Study Platform

NCT04663776

COMPLETED Phase 1

Safety of Inhaled Hydrogen Gas Mixtures in Healthy Volunteers

NCT04046211

COMPLETED

HEALthy Brain and Child Development Study - COVID-19 Supplement

NCT04713150

COMPLETED Phase 4

Bilateral Continuous Erector Spinae Blocks for Post-Sternotomy Pain Management

NCT04567407

COMPLETED NA

Just-In-Time Rapid Cycle Deliberate Practice Simulation Intubation Training Among Novice Pediatric Anesthesia Trainees: A Randomized Control Study

NCT04472195

COMPLETED

Adolescent SCreening To Help Eliminate Misuse

NCT04200339

COMPLETED NA

Ready for Change: Enhancing Motivational Engagement Prior to IIPT

NCT04093921

COMPLETED

The PAWS-COVID-19 (Pediatric AirWay complicationS COVID-19) Registry

NCT04449042

COMPLETED

Patient Forward Access to Clinical and Technological Research: Genetic Influences on Cancer and Atopic Dermatitis

NCT04362852

COMPLETED

The Relationship Between Having a Positive Mindset and Exercise Capacity in Patients With Congenital Heart Disease

NCT03912025

COMPLETED NA

Tele-Coaching Intervention to Improve Treatment Adherence in Cystic Fibrosis

NCT03921229

COMPLETED Phase 2

Cabergoline for the Treatment of Chronic Pain Due to Endometriosis

NCT03928288

COMPLETED

3D Cine Cardiovascular Magnetic Resonance

NCT03583775

TERMINATED NA

Pre Bypass Ultrafiltration (PBUF) in Children Requiring Cardiopulmonary Bypass

NCT03576534

COMPLETED NA

Assessment of Right Ventricular Volume in Pediatric Patients

NCT04099810

COMPLETED NA

Clinical Utility of the 1-minute Sit to Stand Test as a Measure of Submaximal Exercise Tolerance in Patients With Cystic Fibrosis During Acute Pulmonary Exacerbation

NCT04058548

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Phase Distribution

PhaseTrial count
Phase 1 30
Phase 2 23
Phase 3 12
Phase 4 23

What is open in the Boston Children's Hospital pipeline

110 recruiting of 462 indexed (24% open); 268 completed (58%).

Phase mix: 35 late (III/IV) vs 53 early (I/II) (early-phase heavy).

Top condition: Congenital Heart Disease (9 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Boston Children's Hospital: open-pipeline peers nationwide

Peers matched on 462 registered trials and 24% open enrollment, not the therapeutic-area sidebar.

Boston Children's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0200400600 5%10%15%20%25% Total trials Recruiting share Boston Children's HospitalUniversity of VirginiaMedical College of WisconsinAlliance for Clinical Trials in OncologyFred Hutchinson Cancer CenterAdventHealth Translational Research InstituteAuburn UniversityChugai PharmaceuticalHALEON
Boston Children's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Boston Children's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 462 trials (± recruiting share)

Sponsors near 24% open enrollment (± trial volume)

What to do with this Boston Children's Hospital page

462 registered trials is a research-attention snapshot, not an endorsement of Boston Children's Hospital or any single study.

  • 110 of Boston Children's Hospital's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Congenital Heart Disease is the condition Boston Children's Hospital studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Congenital Heart Disease trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Boston Children's Hospital pipeline card: 462 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.