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NCT03263325 · ClinicalTrials.gov registry record
Evaluation of UDP-glucose as a Urinary Biomarker for Early Detection of Cardiac Surgery-associated Pediatric Acute Kidney Injury
A clinical trial, sponsored by Boston Children's Hospital.
- Active
- Registry status
- 305
- Enrollment target
NCT03263325: Active study, sponsored by Boston Children's Hospital.
NCT03263325 is a clinical trial that is active but no longer recruiting, run by Boston Children's Hospital. The registered enrollment target is 305 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03263325 is active but no longer recruiting, sponsored by Boston Children's Hospital.
- ACTIVE NOT RECRUITING
- Registry status
- 305 participants
- Enrollment target
Study Summary
Acute kidney injury (AKI) is common in children after cardiac surgery with a reported incidence of 20-40%. Pediatric AKI has been found to be associated with important short and long-term adverse outcomes. A major challenge to management of AKI after cardiac surgery and cardiopulmonary bypass is the lack of early diagnostic markers. Current diagnostic criteria for AKI in children relies exclusively on elevation of serum creatinine concentration and oliguria. Both of these markers lack sensitivity and specificity, and result in delayed detection of kidney injury. This study aims to determine if UDP-glucose can be used as a urinary biomarker to detect subclinical acute kidney injury following pediatric cardiac surgery with cardiopulmonary bypass.
Primary Outcome
development of AKI
Interventions
- OTHER Discarded urine sample
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 305 participants |
| Start Date | 2017-10-25 |
| Est. Completion | 2027-02-01 |
What the registry record for NCT03263325 still lists
NCT03263325 is an observational study that tracks outcomes without assigning an intervention. The registered 305 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 1 intervention - of which Discarded urine sample is the first listed.
NCT03263325 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03263325 about?
NCT03263325 is a clinical study titled "Evaluation of UDP-glucose as a Urinary Biomarker for Early Detection of Cardiac Surgery-associated Pediatric Acute Kidney Injury". Acute kidney injury (AKI) is common in children after cardiac surgery with a reported incidence of 20-40%. Pediatric AKI has been found to be associated with important short and long-term adverse outcomes. A major challenge to management of AKI after cardiac surgery and cardiopulmonary bypass is th...
What is the current status of trial NCT03263325?
This trial is currently active not recruiting. The enrollment target is 305 participants. The study started on 2017-10-25. Estimated completion is 2027-02-01.
What interventions are being tested in trial NCT03263325?
The interventions under investigation include: Discarded urine sample (OTHER).
Who is sponsoring clinical trial NCT03263325?
This trial is sponsored by Boston Children's Hospital, which has 462 total clinical trials registered on ClinicalTrials.gov.
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