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Type 2 Diabetes: full-pipeline trial registry
120 of 328 indexed Type 2 Diabetes trials are currently recruiting.
Corpus placement: #22 of 28,707 conditions by registered trial count.
328 US clinical trials · 120 currently recruiting · #22 of 28,707 conditions by registered trial count
Type 2 Diabetes: 328 US clinical trials tracked, 120 recruiting.
Type 2 Diabetes is the subject of 328 registered US clinical trials on ClinicalTrials.gov, 120 of them currently open to new participants. 60 are in Phase 3-4 (later-stage) and 50 in Phase 1-2 (earlier-stage). The most active sponsor is Eli Lilly and Company, running 20 of these trials.
Enrollment posture brief
Registry condition type-2-diabetes
OPEN 120 | RECR 37% | LATE 60 | EARLY 50 | RANK #22 | SPON 20
Volume-matched condition peers
Nearest open-share peer: Advanced Cancer (37% recruiting · 123 trials)
Type 2 Diabetes lists 120 open slots (37% of 328 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Type 2 Diabetes on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Type 2 Diabetes recruits in line with its size-band peers.
120 of 328 indexed trials (36.6%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Type 2 Diabetes trials is spread across many organizations.
Eli Lilly and Company accounts for 20 of 328 trials (6.1%). 153 distinct sponsors appear on at least one study for this condition label.
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Typical Type 2 Diabetes enrolment sits around 96 participants.
Median target enrolment is 96 among the 328 trials that report a genuine target (sentinel values excluded). 166 of those (50.6%) plan for fewer than 100 participants.
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Type 2 Diabetes research is mostly interventional.
290 interventional and 38 observational studies make up this index (88.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
328 total, page 1 of 7
PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes
Brigham and Women's Hospital
NCT05390892
'Ai Pono Cooking Demonstrations
University of Hawaii
NCT06526650
Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)
Sparrow Pharmaceuticals
NCT07296484
A Master Protocol for Orforglipron (LY3502970) in Participants With Obesity or Overweight With and Without Type 2 Diabetes
Eli Lilly and Company
NCT06993792
Youth-Onset Type 2 Diabetes and Heart Disease: The Young at Heart Prospective Cohort Study
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT06730113
The CARING Study: Creating and Restoring Health Through Nutrition Guidance
Physicians Committee for Responsible Medicine
NCT05795439
Military Health and Nutrition Examination Study
Pennington Biomedical Research Center
NCT06380322
A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Type 2 Diabetes
Eli Lilly and Company
NCT06972472
Leveraging Videos and Community Health Workers to Address Social Determinants of Health in Immigrants
NYU Langone Health
NCT06319716
ACCESS 2: AI for pediatriC diabetiC Eye examS Study 2
Johns Hopkins University
NCT05463289
Enhancing Preventative Health Behaviors Among Emergency Department Hyperglycemic Patients
Rutgers, The State University of New Jersey
NCT06663813
Latinos Understanding the Need for Adherence in Diabetes Using E-Health
San Diego State University
NCT05570734
Novel Digital Patient-Reported Outcomes Tool for Diabetes Management
NYU Langone Health
NCT05884775
Black Impact: The Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health Intervention
Ohio State University
NCT06055036
NT-ProBNP-based Heart Failure Screening and Prevention Trial in Patients With Type 2 Diabetes: STRONG-DM Study
University of Texas Southwestern Medical Center
NCT06593327
Gut Microbiota in Metabolic Surgery
Vanderbilt University Medical Center
NCT05000996
Implementing an Effective Diabetes Intervention Among Low-Income Immigrants
NYU Langone Health
NCT06319703
Safety and Effectiveness of Endoscopic Intestinal Re-Cellularization Therapy in Individuals With Type II Diabetes
Endogenex
NCT06267391
Effectiveness of the Diabetes Homeless Medication Support (D-HOMES) Program on Diabetes Management
Katherine Vickery
NCT07091487
A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide
Eli Lilly and Company
NCT06897475
Primary Care Pragmatic, Real World Experience for Automated Insulin Delivery
University of Colorado, Denver
NCT07011147
Promoting Alternatives to Sulfonylureas to Improve Patient Safety in Type 2 Diabetes
Ian J. Neeland, MD
NCT05933174
The GRoceries Aimed at Increasing Nutrition Study
University of Pennsylvania
NCT07167004
PILI 'Āina Household
University of Hawaii
NCT06526273
Understanding and Addressing Risks of Low Socioeconomic Status and Diabetes for Heart Failure
Johns Hopkins University
NCT06364644
A Study of LY4086940 in Healthy Participants and Participants With Overweight or Obesity, With or Without Type 2 Diabetes
Eli Lilly and Company
NCT06945419
Diabetes Electronic Prompt for Improved Care Coordination and Treatment in the ED
Rutgers, The State University of New Jersey
NCT06899191
Treating Early Type 2 Diabetes by Reducing Postprandial Glucose Excursions: A Paradigm Shift in Lifestyle Modification
Chiara Fabris, PhD
NCT05766735
More Fresh Fruit and Vegetable Prescription Program for Families With Type 2 Diabetes Mellitus
University of California, San Diego
NCT05138432
Polypill for Prevention of Cardiomyopathy
University of Texas Southwestern Medical Center
NCT06143566
Food and Fitness With Medicine (FFWM)
Ohio State University
NCT07027995
iGlucose® Remote Patient Monitoring Device as an Adjunct to Routine Glucose Meter Devices for Glycemic Management and Control in Gestational Diabetes
The University of Texas Health Science Center, Houston
NCT04206748
Understanding Metabolism and Inflammation Risks for Diabetes in Adolescents
University of Michigan
NCT06007404
Implementation of Team Clinic for Type 2 Diabetes (TCT2)
Children's Hospital Los Angeles
NCT06923046
Role of Microvascular Insulin Resistance and Cardiorespiratory Fitness Diabetes
University of Colorado, Denver
NCT04791371
Addressing Barriers to Achieving Cardiometabolic Disorders Prevention and Treatment Goals for PLWH in the SE US
Duke University
NCT05129345
Diabetes Reversal Online Program and Study (DROP Study)
Physicians Committee for Responsible Medicine
NCT05572502
Health Without Barriers/Salud Sin Barreras- Northern Colorado
Colorado State University
NCT06822387
NAD Augmentation in Diabetes Kidney Disease
Brigham and Women's Hospital
NCT05759468
GLUCOSE-MGH: Genetic Links Understood Through Challenge With Oral Semaglutide Exposure at MGH
Massachusetts General Hospital
NCT06003153
Subclinical Primary Aldosteronism in Diabetes At-Risk for Kidney Disease
Brigham and Women's Hospital
NCT06190158
Successfully Achieving and Maintaining Euglycemia During Pregnancy for Type 2 Diabetes Through Technology and Coaching
Ohio State University
NCT05662462
The Diabetes Staging System in Patient Aligned Care Teams
Durham VA Medical Center
NCT06142006
Outcomes of Physiologic Insulin Resensitization (PIR) in Patients With Chronic Kidney Disease and Type 2 Diabetes Mellitus
Well Cell Global
NCT07187479
Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Type 2 Diabetes (T2D)
Washington University School of Medicine
NCT05277558
Preventing T2DM After GDM With Immediate Postpartum Screening
University of Massachusetts, Worcester
NCT06457139
A Randomized Controlled Trial of Diabetes Screening Immediately Postpartum (DIP) and Follow Up PP CARE
Ohio State University
NCT05909046
Time-restricted Eating for Patients With Type 2 Diabetes
Justin (Matt) Thomas
NCT07318207
Time Limited Eating in Adolescents With Type 2 Diabetes (KT2D)
Children's Hospital Los Angeles
NCT04536480
Assessing the Efficacy of Targeted Home Visits in the Management of Chronic Conditions
University of Texas Southwestern Medical Center
NCT05168605
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 25 |
| Phase 2 | 25 |
| Phase 3 | 35 |
| Phase 4 | 25 |
Top Sponsors
Named interventions
Most-linked intervention names on Type 2 Diabetes records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Type 2 Diabetes trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Type 2 Diabetes page
328 registered trials, 120 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 120 Type 2 Diabetes trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Eli Lilly and Company sponsors the most Type 2 Diabetes trials on record, review their full trial history before evaluating a specific study. See Eli Lilly and Company's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Type 2 Diabetes condition card totals 328 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.