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NCT05277558 · ClinicalTrials.gov registry record

Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Type 2 Diabetes (T2D)

A clinical trial of Inflammation and Insulin Resistance, sponsored by Washington University School of Medicine.

Recruiting
Registry status
117
Enrollment target
2
Study locations

NCT05277558 is a study of Inflammation and Insulin Resistance that is actively recruiting participants, run by Washington University School of Medicine. The registered enrollment target is 117 participants, below the 287-participant average among 132 other Inflammation trials with a reported enrollment target (59% lower). The trial reports 2 study locations across 2 states.

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The verdict

NCT05277558, a study of Inflammation and Insulin Resistance, is actively recruiting participants, sponsored by Washington University School of Medicine.

RECRUITING
Registry status
117 participants
Enrollment target
2
Study locations

Study Summary

Investigators propose to study youth across the spectrum of body mass index (BMI) and dysglycemia. This approach will allow investigators to disentangle the relationship of key features of type 2 diabetes (T2D) risk (e.g. obesity) with intermediary physiologic changes (e.g. insulin resistance, inflammation, β-cell dysfunction and dysglycemia) that pose a risk for the brain. Investigators will determine which of these factors are most associated with differences in brain structure and function among groups, over time, and how these effects differ from normal neurodevelopment.

Interventions

  • OTHER Observational

Study Locations (2)

Missouri

  • Washington University School of Medicine - St Louis

Pennsylvania

  • UPMC Children's Hospital of Pittsburgh - Pittsburgh

Trial Details

FieldValue
Enrollment Target 117 participants
Start Date 2022-05-24
Est. Completion 2027-10-31

What the Registry Record Tells You About NCT05277558

The ClinicalTrials.gov registry entry for NCT05277558 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 117 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 287-participant average among 132 other Inflammation trials with a reported enrollment target (59% lower). The listed sponsor is Washington University School of Medicine, which has 1,502 total studies on file at ClinicalTrials.gov.

The record links to 10 conditions, with Inflammation appearing as the primary indexed condition, and to 1 intervention - of which Observational is the first listed.

NCT05277558 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Missouri, Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT05277558 about?

NCT05277558 is a clinical study titled "Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Type 2 Diabetes (T2D)". Investigators propose to study youth across the spectrum of body mass index (BMI) and dysglycemia. This approach will allow investigators to disentangle the relationship of key features of type 2 diabetes (T2D) risk (e.g. obesity) with intermediary physiologic changes (e.g. insulin resistance, infla...

What is the current status of trial NCT05277558?

This trial is currently recruiting. The enrollment target is 117 participants. The study started on 2022-05-24. Estimated completion is 2027-10-31.

What conditions does trial NCT05277558 study?

This clinical trial studies the following conditions: Inflammation, Insulin Resistance, Obesity, Childhood, Type2 Diabetes, Dysglycemia.

What interventions are being tested in trial NCT05277558?

The interventions under investigation include: Observational (OTHER).

Who is sponsoring clinical trial NCT05277558?

This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05277558 being conducted?

This trial has 2 study locations across Missouri, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.