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ClinicalTrials.gov 103 recruiting now full pipeline #30 of 28,963 conditions

Type 2 Diabetes: full-pipeline trial registry

103 of 289 indexed Type 2 Diabetes trials are currently recruiting.

Corpus placement: #30 of 28,963 conditions by registered trial count.

289 US clinical trials · 103 currently recruiting · #30 of 28,963 conditions by registered trial count

Type 2 Diabetes: 289 US clinical trials tracked, 103 recruiting.

Type 2 Diabetes is the subject of 289 registered US clinical trials on ClinicalTrials.gov, 103 of them currently open to new participants. 56 are in Phase 3-4 (later-stage) and 42 in Phase 1-2 (earlier-stage). The most active sponsor is Eli Lilly and Company, running 20 of these trials.

Open enrollment snapshot

Type 2 Diabetes has 289 registered US clinical trials, 103 of them open to new participants right now, about 36% of the total.

103
recruiting participants now
36%
of trials open to enrollment
56
in Phase 3-4 (later-stage)
20
top sponsor: Eli Lilly and Company

Corpus placement: #30 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.

Key findings

What ClinicalTrials.gov does not surface for Type 2 Diabetes on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.

  1. Type 2 Diabetes recruits in line with its size-band peers.

    103 of 289 indexed trials (35.6%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Type 2 Diabetes trials is spread across many organizations.

    Eli Lilly and Company accounts for 20 of 289 trials (6.9%). 140 distinct sponsors appear on at least one study for this condition label.

  3. Typical Type 2 Diabetes enrolment sits around 96 participants.

    Median target enrolment is 96 among the 289 trials that report a genuine target (sentinel values excluded). 145 of those (50.2%) plan for fewer than 100 participants.

  4. Type 2 Diabetes research is mostly interventional.

    257 interventional and 32 observational studies make up this index (88.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 121Phase 221Phase 334Phase 422

Open and recent trials

289 total, page 2 of 6

RECRUITING 74 participants

Designing Team Clinic for Youth With Type 2 Diabetes

Children's Hospital Los Angeles

NCT06658743

RECRUITING NA 72 participants

Personalized Nutrition for Type 2 Diabetes

University of Minnesota

NCT06784375

RECRUITING NA 70 participants

Families Implementing Good Health Traditions for Life

Morehouse School of Medicine

NCT07441655

RECRUITING NA 70 participants

Effect of Sleep Extension on Ceramides in People with Overweight and Obesity

University of Utah

NCT06180837

RECRUITING Phase 1 64 participants

SGLT2i, Pioglitazone, and Ketone Production in T2D

The University of Texas Health Science Center at San Antonio

NCT07053319

RECRUITING NA 60 participants

Nutrition+: Effect of a High-Protein Diabetes Formula on Body Composition in Type 2 Diabetes Patients Treated With Incretin Mimetics

Joslin Diabetes Center

NCT07271043

RECRUITING NA 60 participants

Pilot of Continuous Glucose Monitor-Augmented Food Is Medicine

University of North Carolina, Chapel Hill

NCT07148713

RECRUITING Phase 2 60 participants

The Effect of Glycemic Control and of GLP-1 Receptor Agonism on Islet GLP-1 in People With Type 1 and Type 2 Diabetes

Mayo Clinic

NCT06976619

RECRUITING NA 60 participants

Extracellular Vesicles, Insulin Action, and Exercise

Rutgers, The State University of New Jersey

NCT06546085

RECRUITING NA 60 participants

Improving Appetite Self-Regulation in African American Adults With Type 2 Diabetes

University of North Carolina, Chapel Hill

NCT05741125

RECRUITING NA 60 participants

ACT Intervention for Type 2 Diabetes Management for Rural and Underserved Community

Sam Houston State University

NCT06028503

RECRUITING NA 60 participants

Type 2 Continuous Glucose Monitoring Academy

Children's Hospital Los Angeles

NCT06516640

RECRUITING Early Phase 1 60 participants

Role of Autophagy in Type 2 Diabetes Microvascular Dysfunction

Medical College of Wisconsin

NCT05593549

RECRUITING Phase 4 60 participants

Quantifying Hepatic Mitochondrial Fluxes in Humans

The University of Texas Health Science Center at San Antonio

NCT05305287

RECRUITING Phase 1 56 participants

A Study of PATAS Trifluoroacetate Using Single Ascending Doses in Healthy Volunteers

AdipoPharma

NCT07223333

RECRUITING Phase 3 55 participants

A Study of Dulaglutide (LY2189265) 3.0 mg and 4.5 mg in Pediatric Participants With Type 2 Diabetes Mellitus (AWARD-PEDS PLUS)

Eli Lilly and Company

NCT06739122

RECRUITING NA 50 participants

Enhancing Telemedicine for T2D

University of Pittsburgh

NCT06740435

RECRUITING NA 50 participants

The Role of Type 2 Diabetes on Skeletal Muscle Atrophy and Recovery Following Bed Rest in Older Adults

AdventHealth Translational Research Institute

NCT03761446

RECRUITING Phase 4 50 participants

Glycemic and Weight Loss Effects of GLP-1R Agonist Therapy in Subjects With Spinal Cord Injury and Type 2 Diabetes

Marzieh Salehi

NCT06706284

RECRUITING NA 46 participants

A Randomized Double-Blinded and Placebo-Controlled Trial to Assess the Efficacy of Biophoton Therapy to Treat Type 2 Diabetes

First Institute of All Medicines

NCT07124208

RECRUITING NA 43 participants

The Food for Health Study

University of Montana

NCT07254689

RECRUITING NA 42 participants

Diabetes Body Project 2

Joslin Diabetes Center

NCT07468188

RECRUITING Phase 2 40 participants

Renal Mechanism of SGLT2 Inhibition

University of Colorado, Denver

NCT05507892

RECRUITING 40 participants

Liver Transplant CGM

Icahn School of Medicine at Mount Sinai

NCT07216508

RECRUITING NA 40 participants

Mobile App Logging for Diabetes in Pregnancy

Carolyn Zahler-Miller

NCT06005987

RECRUITING NA 40 participants

A Low-Carb Approach to Treat Type 2 Diabetes in Pediatric Patients

University of Alabama at Birmingham

NCT06902077

RECRUITING NA 40 participants

Mobile Health Dietary Intervention for Stroke Survivors With Prediabetes or Type 2 Diabetes

University of Hawaii

NCT07120334

RECRUITING NA 40 participants

Ketogenic Diet and Diabetes Demonstration Project

University of New Mexi

NCT06115265

RECRUITING 36 participants

Fitbit and AI Chatbot in Sedentary Primary Care Patients With T2D

University of Colorado, Denver

NCT07005362

RECRUITING Phase 4 34 participants

DiEtary Sodium Intake Effects on Ertugliflozin-induced Changes in GFR, reNal Oxygenation and Systemic Hemodynamics: the DESIGN Study, a Randomized, Placebo-controlled, Cross-over Study With Ertugliflozin in People With Type 2 Diabetes

Amsterdam UMC, location VUmc

NCT06983054

RECRUITING NA 30 participants

Ultrasound Effects on Glycemic Control in T2DM

Yale University

NCT05354947

RECRUITING NA 30 participants

High Fructose Diet, the Gut Microbiome, and Metabolic Health

Icahn School of Medicine at Mount Sinai

NCT06329544

RECRUITING NA 30 participants

Developing and Testing a Self-Compassion Tool Kit to Improve the Care of Individuals With Type 2 Diabetes

University of California, San Diego

NCT06398093

RECRUITING NA 30 participants

Exercise and Protein Efficiency in T2D

University of Illinois at Urbana-Champaign

NCT07477067

RECRUITING NA 30 participants

Effects of Ketone Ester Consumption on Exercise Tolerance and Cardiac Function

Ohio State University

NCT06078683

RECRUITING Phase 1 30 participants

THC Effects on Glucose in Type 2 Diabetes

University of California, San Diego

NCT05322213

RECRUITING NA 30 participants

Arginine Metabolism in Youth With Type 2 Diabetes

Baylor College of Medicine

NCT05477134

RECRUITING NA 30 participants

Using Continuous Glucose Monitoring to Quantify the Effects of NOURISH's Culturally Modified Meals on Asian Americans With Type 2 Diabetes

Stanford University

NCT06836479

RECRUITING Phase 1 30 participants

SGLTi, Hepatic Glucose Production and Ketogenesis

The University of Texas Health Science Center at San Antonio

NCT05960656

RECRUITING Phase 1 29 participants

SGLT2i, Ketoacidosis, Volume Contraction, and Insulinopenia

The University of Texas Health Science Center at San Antonio

NCT07053306

RECRUITING NA 25 participants

Glycemic Excursion Minimization (GEM) to Outshine Health Disparities

Catherine Davis

NCT06236581

RECRUITING Phase 1 24 participants

Heat Therapy in Type 2 Diabetes

Purdue University

NCT06596967

RECRUITING Early Phase 1 22 participants

SGLT2i, Hepatic Glucose Production, and SNS

The University of Texas Health Science Center at San Antonio

NCT07053293

RECRUITING Phase 4 20 participants

Mechanism of SGLT2 Inhibition in the Kidney

University of Michigan

NCT06291155

RECRUITING 20 participants

Enhancing Diabetes Care: Exposome &Amp; Sensors

University of Illinois at Chicago

NCT06989008

RECRUITING Early Phase 1 20 participants

Precision Dosing of Metformin in Youth With T2D

University of California, San Francisco

NCT06120881

RECRUITING NA 20 participants

Circadian Intervention to Improve Cardiometabolic Health

University of Utah

NCT05943626

RECRUITING 20 participants

Pharmacist-led Continuous Glucose Monitoring

University of South Florida

NCT06572306

RECRUITING NA 17 participants

Continuous Glucose Monitors (CGMs) for All: Studying the Impact of Expanding CGM Access

Yale University

NCT06658067

RECRUITING NA 12 participants

Dynamic in Vivo PET Imaging and ex Vivo Biopsies From Skeletal Muscle and Adipose Tissue to Investigate the Effects of Exercise on Insulin Resistance and Mitochondrial Energetics in Type 2 Diabetes

AdventHealth Translational Research Institute

NCT04754581

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Phase Distribution

PhaseTrial count
Phase 1 21
Phase 2 21
Phase 3 34
Phase 4 22

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What is open for Type 2 Diabetes right now

103 recruiting of 289 indexed (36% open).

Phase mix: 56 late (III/IV) vs 42 early (I/II) (balanced across stages).

Top sponsor: Eli Lilly and Company (20 trials), 9 others listed. 50 shown below, recruiting first. #30 of 28,963 conditions by registered trial count.

How open-enrollment share is computed

Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.

Frequently Asked Questions

How many clinical trials are there for Type 2 Diabetes?

PlainTrial tracks 289 US clinical trials for Type 2 Diabetes, of which 103 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Type 2 Diabetes?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.