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Type 2 Diabetes: full-pipeline trial registry
120 of 328 indexed Type 2 Diabetes trials are currently recruiting.
Corpus placement: #22 of 28,707 conditions by registered trial count.
328 US clinical trials · 120 currently recruiting · #22 of 28,707 conditions by registered trial count
Type 2 Diabetes: 328 US clinical trials tracked, 120 recruiting.
Type 2 Diabetes is the subject of 328 registered US clinical trials on ClinicalTrials.gov, 120 of them currently open to new participants. 60 are in Phase 3-4 (later-stage) and 50 in Phase 1-2 (earlier-stage). The most active sponsor is Eli Lilly and Company, running 20 of these trials.
Enrollment posture brief
Registry condition type-2-diabetes
OPEN 120 | RECR 37% | LATE 60 | EARLY 50 | RANK #22 | SPON 20
Volume-matched condition peers
Nearest open-share peer: Advanced Cancer (37% recruiting · 123 trials)
Type 2 Diabetes lists 120 open slots (37% of 328 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Type 2 Diabetes on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Type 2 Diabetes recruits in line with its size-band peers.
120 of 328 indexed trials (36.6%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Type 2 Diabetes trials is spread across many organizations.
Eli Lilly and Company accounts for 20 of 328 trials (6.1%). 153 distinct sponsors appear on at least one study for this condition label.
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Typical Type 2 Diabetes enrolment sits around 96 participants.
Median target enrolment is 96 among the 328 trials that report a genuine target (sentinel values excluded). 166 of those (50.6%) plan for fewer than 100 participants.
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Type 2 Diabetes research is mostly interventional.
290 interventional and 38 observational studies make up this index (88.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
328 total, page 2 of 7
Joint Patient and Caregiver Intervention for Older African Americans With Type 2 Diabetes
Medical College of Wisconsin
NCT06279637
Diabetes Education/Skills Training and Social Needs Resolution Intervention
Medical College of Wisconsin
NCT05935410
My ESSENCE - A Research Study on Mindfulness for African-Americans With Type 2 Diabetes
University of Illinois at Chicago
NCT05208164
Sleep and Glycemic Control in Type 2 Diabetes Adolescents
Children's Hospital of Philadelphia
NCT04213547
Digital Health Navigation for Latino Patients With Type II Diabetes
Brigham and Women's Hospital
NCT06283992
Mechanisms of Fatigability With Diabetes
University of Michigan
NCT04442451
New T-UP: Engaging Vulnerable Students in Diabetes Prevention
University of California, Los Angeles
NCT07225218
IH, Brain Health, and T2D
Darren P Casey
NCT07173543
Effect of Meal Composition and Timing Modification on Glucose Metabolism, Body Temperature and Sleep
Stanford University
NCT05413928
Designing Team Clinic for Youth With Type 2 Diabetes
Children's Hospital Los Angeles
NCT06658743
Personalized Nutrition for Type 2 Diabetes
University of Minnesota
NCT06784375
Ketones, SGLT2, HFrEF
The University of Texas Health Science Center at San Antonio
NCT06229678
Families Implementing Good Health Traditions for Life
Morehouse School of Medicine
NCT07441655
Effect of Sleep Extension on Ceramides in People with Overweight and Obesity
University of Utah
NCT06180837
SGLT2i, Pioglitazone, and Ketone Production in T2D
The University of Texas Health Science Center at San Antonio
NCT07053319
Nutrition+: Effect of a High-Protein Diabetes Formula on Body Composition in Type 2 Diabetes Patients Treated With Incretin Mimetics
Joslin Diabetes Center
NCT07271043
Pilot of Continuous Glucose Monitor-Augmented Food Is Medicine
University of North Carolina, Chapel Hill
NCT07148713
The Effect of Glycemic Control and of GLP-1 Receptor Agonism on Islet GLP-1 in People With Type 1 and Type 2 Diabetes
Mayo Clinic
NCT06976619
Extracellular Vesicles, Insulin Action, and Exercise
Rutgers, The State University of New Jersey
NCT06546085
Improving Appetite Self-Regulation in African American Adults With Type 2 Diabetes
University of North Carolina, Chapel Hill
NCT05741125
ACT Intervention for Type 2 Diabetes Management for Rural and Underserved Community
Sam Houston State University
NCT06028503
Type 2 Continuous Glucose Monitoring Academy
Children's Hospital Los Angeles
NCT06516640
Role of Autophagy in Type 2 Diabetes Microvascular Dysfunction
Medical College of Wisconsin
NCT05593549
Quantifying Hepatic Mitochondrial Fluxes in Humans
The University of Texas Health Science Center at San Antonio
NCT05305287
A Study of PATAS Trifluoroacetate Using Single Ascending Doses in Healthy Volunteers
AdipoPharma
NCT07223333
A Study of Dulaglutide (LY2189265) 3.0 mg and 4.5 mg in Pediatric Participants With Type 2 Diabetes Mellitus (AWARD-PEDS PLUS)
Eli Lilly and Company
NCT06739122
Type 2 Diabetes and Blood Brain Barrier Improvement
University of California, Los Angeles
NCT06322212
Enhancing Telemedicine for T2D
University of Pittsburgh
NCT06740435
The Role of Type 2 Diabetes on Skeletal Muscle Atrophy and Recovery Following Bed Rest in Older Adults
AdventHealth Translational Research Institute
NCT03761446
Glycemic and Weight Loss Effects of GLP-1R Agonist Therapy in Subjects With Spinal Cord Injury and Type 2 Diabetes
Marzieh Salehi
NCT06706284
A Randomized Double-Blinded and Placebo-Controlled Trial to Assess the Efficacy of Biophoton Therapy to Treat Type 2 Diabetes
First Institute of All Medicines
NCT07124208
The Food for Health Study
University of Montana
NCT07254689
Diabetes Body Project 2
Joslin Diabetes Center
NCT07468188
Renal Mechanism of SGLT2 Inhibition
University of Colorado, Denver
NCT05507892
Liver Transplant CGM
Icahn School of Medicine at Mount Sinai
NCT07216508
Mobile App Logging for Diabetes in Pregnancy
Carolyn Zahler-Miller
NCT06005987
A Low-Carb Approach to Treat Type 2 Diabetes in Pediatric Patients
University of Alabama at Birmingham
NCT06902077
Mobile Health Dietary Intervention for Stroke Survivors With Prediabetes or Type 2 Diabetes
University of Hawaii
NCT07120334
Ketogenic Diet and Diabetes Demonstration Project
University of New Mexi
NCT06115265
Non-weight Bearing Exercise for Accelerated Healing of Diabetic Foot Ulcers
University of Michigan
NCT05603273
A Causative Role for Amylin in Diabetic Peripheral Neuropathy
Zabeen Mahuwala, MD
NCT03481283
Fitbit and AI Chatbot in Sedentary Primary Care Patients With T2D
University of Colorado, Denver
NCT07005362
DiEtary Sodium Intake Effects on Ertugliflozin-induced Changes in GFR, reNal Oxygenation and Systemic Hemodynamics: the DESIGN Study, a Randomized, Placebo-controlled, Cross-over Study With Ertugliflozin in People With Type 2 Diabetes
Amsterdam UMC, location VUmc
NCT06983054
Ultrasound Effects on Glycemic Control in T2DM
Yale University
NCT05354947
High Fructose Diet, the Gut Microbiome, and Metabolic Health
Icahn School of Medicine at Mount Sinai
NCT06329544
Developing and Testing a Self-Compassion Tool Kit to Improve the Care of Individuals With Type 2 Diabetes
University of California, San Diego
NCT06398093
Exercise and Protein Efficiency in T2D
University of Illinois at Urbana-Champaign
NCT07477067
Effects of Ketone Ester Consumption on Exercise Tolerance and Cardiac Function
Ohio State University
NCT06078683
THC Effects on Glucose in Type 2 Diabetes
University of California, San Diego
NCT05322213
Arginine Metabolism in Youth With Type 2 Diabetes
Baylor College of Medicine
NCT05477134
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 25 |
| Phase 2 | 25 |
| Phase 3 | 35 |
| Phase 4 | 25 |
Top Sponsors
Named interventions
Most-linked intervention names on Type 2 Diabetes records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Type 2 Diabetes trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Type 2 Diabetes page
328 registered trials, 120 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 120 Type 2 Diabetes trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Eli Lilly and Company sponsors the most Type 2 Diabetes trials on record, review their full trial history before evaluating a specific study. See Eli Lilly and Company's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Type 2 Diabetes condition card totals 328 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.