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ClinicalTrials.gov 104 recruiting now official registry

Solid Tumor clinical trials

104 of 197 indexed Solid Tumor trials are currently recruiting.

197 US clinical trials · 104 currently recruiting

Solid Tumor is the subject of 197 registered US clinical trials on ClinicalTrials.gov, 104 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 165 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 11 of these trials.

The research picture

Solid Tumor has 197 registered US clinical trials, 104 of them open to new participants right now, about 53% of the total.

104
recruiting participants now
53%
of trials open to enrollment
4
in Phase 3–4 (later-stage)
11
top sponsor: Memorial Sloan Kettering Cancer Center
Phase 1150Phase 215Phase 31Phase 43

Active & Recent Trials

197 total, page 3 of 4

RECRUITING Phase 1 18 participants

Cabozantinib in Combination With 13-cis-Retinoic Acid in Children With Relapsed or Refractory Solid Tumors

Peter Zage

NCT03611595

RECRUITING Early Phase 1 15 participants

Phase 0 Master Protocol for CIVO Intratumoral Microdosing of Anti-Cancer Therapies

Presage Biosciences

NCT04541108

RECRUITING Phase 1 13 participants

PET [89Zr]DFO-starPEG in Solid Tumors

Robert Flavell, MD, PhD

NCT06894745

RECRUITING Phase 1 12 participants

Phase I Study VG2025 as a Single Agent and in Combination Therapy With Nivolumab in Subjects With Advanced Malignant Solid Tumors

Virogin Biotech Canada

NCT05266612

ACTIVE NOT RECRUITING Phase 1 552 participants

A Study Evaluating AB248 Alone or in Combination With Pembrolizumab in Adult Patients With Solid Tumors

Asher Biotherapeutics

NCT05653882

ACTIVE NOT RECRUITING 400 participants

MRD Assay Evaluates Recurrence and Response Via a Tumor Informed Assessment

Invitae Corporation

NCT05219734

ACTIVE NOT RECRUITING Phase 1 310 participants

Safety and Preliminary Anti-Tumor Activity of TYRA-300 in Advanced Urothelial Carcinoma and Other Solid Tumors With FGFR3 Gene Alterations

Tyra Biosciences

NCT05544552

ACTIVE NOT RECRUITING Phase 4 297 participants

Extended Treatment Protocol for Subjects Continuing to Benefit From Ibrutinib.

Pharmacyclics Switzerland

NCT03229200

ACTIVE NOT RECRUITING Phase 1 296 participants

Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

Inhibrx Biosciences

NCT04198766

ACTIVE NOT RECRUITING Phase 2 240 participants

SKB264 in Combination With Pembrolizumab in Subjects With Selected Solid Tumors

Klus Pharma

NCT05642780

ACTIVE NOT RECRUITING Phase 1 223 participants

A Study of LY3200882 in Participants With Solid Tumors

Eli Lilly and Company

NCT02937272

ACTIVE NOT RECRUITING Phase 1 200 participants

To Evaluate the Safety, Tolerability, and Pharmacokinetics of Inavolisib Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer

Genentech

NCT03006172

ACTIVE NOT RECRUITING Phase 1 182 participants

Study of GS-4528 in Adults With Solid Tumors

Gilead Sciences

NCT05840224

ACTIVE NOT RECRUITING Phase 1 175 participants

A Study to Find a Suitable Dose of ASP4396 in Adults With Solid Tumors

Astellas Pharma

NCT06364696

ACTIVE NOT RECRUITING Phase 1 169 participants

A Study to Assess Safety, Tolerability, and Pharmacokinetics of ABSK121-NX in Patients With Advanced Solid Tumors

Abbisko Therapeutics Co

NCT05627063

ACTIVE NOT RECRUITING Phase 1 160 participants

A Study to Evaluate the Safety and Efficacy of A2B530, a Logic-gated CAR T, in Participants With Solid Tumors That Express CEA and Have Lost HLA-A*02 Expression

A2 Biotherapeutics

NCT05736731

ACTIVE NOT RECRUITING Phase 1 141 participants

A Phase 1/2a Study of 23ME-00610 in Patients With Advanced Solid Malignancies

23andMe

NCT05199272

ACTIVE NOT RECRUITING Phase 1 138 participants

A Study of TRK-950 in Combinations With Anti-Cancer Treatment Regimens in Patients With Advanced Solid Tumors

Toray Industries

NCT03872947

ACTIVE NOT RECRUITING Phase 1 137 participants

ENB003 Plus Pembrolizumab Phase 1b/2a in Solid Tumors

ENB Therapeutics

NCT04205227

ACTIVE NOT RECRUITING Phase 1 126 participants

Dose Escalation and Dose Expansion Study of CPO-100 in Patients With Advanced Solid Tumors

Conjupro Biotherapeutics

NCT04931823

ACTIVE NOT RECRUITING Phase 2 120 participants

Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes (PRECISION 1)

Aadi Bioscience

NCT05103358

ACTIVE NOT RECRUITING Phase 1 117 participants

Study of PD1 Blockade by Pembrolizumab With Stereotactic Body Radiotherapy in Advanced Solid Tumors

University of Chicago

NCT02608385

ACTIVE NOT RECRUITING Phase 1 106 participants

A Study of NDI 1150-101 in Patients With Solid Tumors

Nimbus Saturn

NCT05128487

ACTIVE NOT RECRUITING 100 participants

Technology to Assess Vulnerable Older Adults With Cancer and Their Caregivers

City of Hope Medical Center

NCT02041416

ACTIVE NOT RECRUITING Phase 1 100 participants

Phase I Study of Autologous CD8+ and CD4+ Engineered T Cell Receptor T Cells in Subjects With Advanced or Metastatic Solid Tumor

Affini-T Therapeutics

NCT06105021

ACTIVE NOT RECRUITING Phase 1 80 participants

Bortezomib With Gemcitabine/Doxorubicin in Patients With Urothelial Cancer and Other Solid Tumors

M.D. Anderson Cancer Center

NCT00479128

ACTIVE NOT RECRUITING Phase 1 70 participants

Study of ARRY-614 Plus Either Nivolumab or Nivolumab+Ipilimumab

Dan Zandberg

NCT04074967

ACTIVE NOT RECRUITING Phase 1 70 participants

TH1902 in Patients With Advanced Solid Tumors

Theratechnologies

NCT04706962

ACTIVE NOT RECRUITING Phase 1 54 participants

A Study of AZD1390 and Stereotactic Body Radiotherapy (SBRT) for People With Metastatic Solid Tumor Cancer

Memorial Sloan Kettering Cancer Center

NCT05678010

ACTIVE NOT RECRUITING Phase 2 51 participants

Study of Benralizumab in People With Skin Side Effects Caused by Cancer Therapies

Memorial Sloan Kettering Cancer Center

NCT04552288

ACTIVE NOT RECRUITING Phase 2 51 participants

A Study to Assess Safety and Efficacy of PRL3-Zumab in Patients With Solid Tumors

Intra-IMMUSG Pte

NCT04452955

ACTIVE NOT RECRUITING Phase 1 50 participants

Ph. 1, Evaluation of Safety, Tolerability, PK, Anti-tumor Activity of STP707 IV in Subjects With Solid Tumors

Sirnaomics

NCT05037149

ACTIVE NOT RECRUITING Phase 1 50 participants

A Pilot Trial of Atorvastatin in Tumor Protein 53 (p53) -Mutant and p53 Wild-Type Malignancies

Joaquina Baranda

NCT03560882

ACTIVE NOT RECRUITING Phase 1 49 participants

A Study of RP-3500 in Combination With Standard Radiation Therapy in People With Solid Tumor Cancer

Memorial Sloan Kettering Cancer Center

NCT05566574

ACTIVE NOT RECRUITING Phase 1 47 participants

Study of PYX-106 in Solid Tumors

Pyxis Oncology

NCT05718557

ACTIVE NOT RECRUITING Phase 1 44 participants

A Dose Escalation Study of HBI-2438 in Patients With Solid Tumors Harboring KRAS G12C Mutation

HUYABIO International

NCT05485974

ACTIVE NOT RECRUITING Phase 1 42 participants

A Dose Escalation Study of SHP2 Inhibitor in Patients With Solid Tumors Harboring KRAS of EGFR Mutations

HUYABIO International

NCT05163028

ACTIVE NOT RECRUITING Phase 1 41 participants

S095029 as Monotherapy and in Combination With Sym021 in Patients With Advanced Solid Tumor Malignancies Followed by an Expansion Part With Triple Combinations in Patients With Metastatic Gastric or Colorectal Cancers

Institut de Recherches Internationales Servier

NCT05162755

ACTIVE NOT RECRUITING Phase 1 40 participants

A Study Evaluating DS-1055a in Participants With Relapsed or Refractory Locally Advanced or Metastatic Solid Tumors

Daiichi Sankyo

NCT04419532

ACTIVE NOT RECRUITING Phase 1 39 participants

Evaluating Safety and Biomarkers Using DK210 (EGFR) for Locally Advanced or Metastatic EGFR+ Tumors

DEKA Biosciences

NCT05704985

ACTIVE NOT RECRUITING Phase 1 35 participants

Dose-Escalation Study of E7727, an Oral Cytidine Deaminase Inhibitor With Oral Decitabine in Subjects With Solid Tumors

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT03875287

ACTIVE NOT RECRUITING Phase 1 33 participants

Ph I/II Trial of Systemic VSV-IFNβ-NIS in Combination With Checkpoint Inhibitor Therapy in Patients With Select Solid Tumors

Vyriad

NCT03647163

ACTIVE NOT RECRUITING Phase 1 31 participants

A Safety And Efficacy Study Of HLA-G- Targeted CAR-T Cells IVS-3001 In Subjects With Previously Treated Advanced HLA-G-Positive Solid Tumors

M.D. Anderson Cancer Center

NCT05672459

ACTIVE NOT RECRUITING Phase 1 30 participants

A Study to Assess the Safety, Pharmacokinetics, and Antitumor Activity of Oral TACH101 in Participants With Advanced or Metastatic Cancer

Tachyon Therapeutics

NCT05076552

ACTIVE NOT RECRUITING Phase 2 30 participants

Study of Tilsotolimod in Combination With Nivolumab and Ipilimumab for the Treatment of Solid Tumors (ILLUMINATE-206)

Idera Pharmaceuticals

NCT03865082

ACTIVE NOT RECRUITING Phase 1 16 participants

QUILT-3.064: PD-L1 t-haNK In Subjects With Locally Advanced Or Metastatic Solid Cancers

ImmunityBio

NCT04050709

ACTIVE NOT RECRUITING Phase 1 14 participants

Safety and Dose Finding Study of Neratinib in Children and Young Adults With Cancer That Has Returned or Not Responded to Treatment

Memorial Sloan Kettering Cancer Center

NCT02932280

ACTIVE NOT RECRUITING Phase 1 14 participants

A Study to Investigate the Safety, Pharmacokinetics, and Preliminary Effectiveness of GSK4418959 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors

GlaxoSmithKline

NCT06710847

ACTIVE NOT RECRUITING Phase 1 12 participants

Interleukin-15 Armored Glypican 3-specific Chimeric Antigen Receptor Expressed in Autologous T Cells for Solid Tumors

Baylor College of Medicine

NCT05103631

COMPLETED 800 participants

Characterization of Methylation Patterns in Cancer and Non-Cancer cfDNA

Nucleix

NCT04264767

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Phase Distribution

PhaseTrial count
Phase 1 150
Phase 2 15
Phase 3 1
Phase 4 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Solid Tumor Trial Landscape

197 indexed Solid Tumor studies · 104 recruiting (53%).

Phase mix: 4 late (III/IV) vs 165 early (I/II).

Top sponsor: Memorial Sloan Kettering Cancer Center (11 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Solid Tumor?

PlainTrial tracks 197 US clinical trials for Solid Tumor, of which 104 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Solid Tumor?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.