Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 104 recruiting now early-phase tilt #53 of 28,707 conditions

Solid Tumor: early-phase trial registry

104 of 197 indexed Solid Tumor trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #53 of 28,707 conditions by registered trial count.

197 US clinical trials · 104 currently recruiting · #53 of 28,707 conditions by registered trial count

Solid Tumor: 197 US clinical trials tracked, 104 recruiting.

Solid Tumor is the subject of 197 registered US clinical trials on ClinicalTrials.gov, 104 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 165 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 11 of these trials.

Enrollment posture brief

Registry condition solid-tumor

OPEN 104 | RECR 53% | LATE 4 | EARLY 165 | RANK #53 | SPON 11

Nearest open-share peer: Metastatic Breast Cancer (53% recruiting · 140 trials)

Solid Tumor (this)53%Type 1 Diabetes39.7%Glioblastoma39%Overweight25.3%Rheumatoid Arthritis18.6%
Open-enrollment share among volume-matched conditions near Solid Tumor

Solid Tumor lists 104 open slots (53% of 197 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Solid Tumor on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Solid Tumor is recruiting above its size-band peers.

    104 of 197 indexed trials (52.8%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Solid Tumor trials is spread across many organizations.

    Memorial Sloan Kettering Cancer Center accounts for 11 of 197 trials (5.6%). 149 distinct sponsors appear on at least one study for this condition label.

  3. Typical Solid Tumor enrolment sits around 80 participants.

    Median target enrolment is 80 among the 197 trials that report a genuine target (sentinel values excluded). 108 of those (54.8%) plan for fewer than 100 participants.

  4. Solid Tumor research is mostly interventional.

    179 interventional and 18 observational studies make up this index (90.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 1150Phase 215Phase 31Phase 43

Open and recent trials

197 total, page 4 of 4

COMPLETED NA 279 participants

Illness Management and Parental Adjustment to Cancer Treatment

Children's Hospital Medical Center, Cincinnati

NCT02505165

COMPLETED 252 participants

Validating Pain Scales in Children and Young Adults

National Cancer Institute (NCI)

NCT01639950

COMPLETED Phase 1 174 participants

A Study of Evorpacept (ALX148) in Patients With Advanced Solid Tumors and Lymphoma (ASPEN-01)

ALX Oncology

NCT03013218

COMPLETED Phase 1 164 participants

A Study of Anti-PD-L1 Checkpoint Antibody (LY3300054) Alone and in Combination in Participants With Advanced Refractory Solid Tumors

Eli Lilly and Company

NCT02791334

COMPLETED Phase 4 163 participants

Durvalumab Long-Term Safety and Efficacy Study

AstraZeneca

NCT04078152

COMPLETED Phase 1 127 participants

Dose-Finding and Safety Study for Oral Single-Agent to Treat Advanced Malignancies

Processa Pharmaceuticals

NCT02030067

COMPLETED Phase 1 119 participants

Phase 1/2 Study of Derazantinib (ARQ 087) in Adult Subjects With Advanced Solid Tumors With FGFR Genetic Alterations

Basilea Pharmaceutica

NCT01752920

COMPLETED Phase 1 114 participants

Study of Mogamulizumab + Nivolumab in Subjects w/Locally Advanced or Metastatic Solid Tumors

Kyowa Kirin

NCT02705105

COMPLETED NA 92 participants

Individualized Stereotactic Body Radiotherapy of Liver Metastases

Massachusetts General Hospital

NCT01239381

COMPLETED Phase 1 89 participants

Sym021 Monotherapy, in Combination With Sym022 or Sym023, and in Combination With Both Sym022 and Sym023 in Patients With Advanced Solid Tumor Malignancies or Lymphomas

Symphogen A/S

NCT03311412

COMPLETED Phase 1 88 participants

Phase 1 Trial of Hu5F9-G4, a CD47-targeting Antibody

Gilead Sciences

NCT02216409

COMPLETED Phase 1 80 participants

A Study of of MORAb-004 in Subjects With Solid Tumors

Morphotek

NCT00847054

COMPLETED Phase 1 78 participants

A Phase 1a/b Study of IK-175 as a Single Agent and in Combination With Nivolumab in Patients With Locally Advanced or Metastatic Solid Tumors and Urothelial Carcinoma

Ikena Oncology

NCT04200963

COMPLETED Phase 2 76 participants

A Study to Assess the Potential Effects of a Single-Dose Administration of Trabectedin on the QT Intervals of the Electrocardiogram

Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

NCT00786838

COMPLETED Phase 1 73 participants

A Dose Escalation Study of Radio-labeled Antibody for the Treatment of Advanced Cancer

Fujifilm Pharmaceuticals U.S.A.

NCT02454010

COMPLETED Phase 1 68 participants

Safety, Pharmacokinetics and Clinical Activity of Oral Rigosertib in Solid Tumors

Traws Pharma

NCT01168011

COMPLETED Phase 1 60 participants

A Phase I Dose-Escalation Study of IMGN388 in Patients With Solid Tumors

ImmunoGen

NCT00721669

COMPLETED Phase 1 57 participants

AO-176 in Multiple Solid Tumor Malignancies

Arch Oncology

NCT03834948

COMPLETED Phase 1 54 participants

Capecitabine or 5-Fluorouracil in Combination With Irinotecan and Cisplatin in Patients With Solid Tumor Malignancies

Dana-Farber Cancer Institute

NCT00215501

COMPLETED Phase 1 50 participants

CB-839 + Capecitabine in Solid Tumors and Fluoropyrimidine Resistant PIK3CA Mutant Colorectal Cancer

David Bajor, MD

NCT02861300

COMPLETED Phase 1 48 participants

Indocyanine Green for Solid Tumors

University of Pennsylvania

NCT02280954

COMPLETED Phase 1 46 participants

Study to Assess Safety and Efficacy of the Second Mitochondrial-derived Activator of Caspases (SMAC) Mimetic Debio 1143

Debiopharm International

NCT04122625

COMPLETED Phase 1 46 participants

Study of an Investigational Drug, ASP3026, in Patients With Advanced Malignancies (Solid Tumors and B-Cell Lymphoma)

Astellas Pharma

NCT01284192

COMPLETED Phase 1 45 participants

A Phase 1 Study to Investigate Axatilimab Alone or in Combination With Durvalumab in Patients With Solid Tumors

Syndax Pharmaceuticals

NCT03238027

COMPLETED Phase 1 44 participants

LYT-200 Alone and in Combination With Chemotherapy or Tislelizumab in Patients With Locally Advanced or Metastatic Solid Tumors

PureTech

NCT04666688

COMPLETED 43 participants

The Good Patient Study

St. Jude Children's Research Hospital

NCT02199548

COMPLETED Phase 1 38 participants

A Study to Evaluate the Safety, Tolerability, MTD, PK, and Activity of Oraxol in Subjects w Adv. Malignancies

Athenex

NCT02730481

COMPLETED 31 participants

Immune Reconstitution in Oncology Patients Following Autologous Stem Cell Transplant

St. Jude Children's Research Hospital

NCT01540175

COMPLETED Phase 1 29 participants

Clinical Trial of the Combination of Intravenous Alvespimycin (KOS-1022), Trastuzumab With or Without Paclitaxel in Patients With Advanced Solid Tumor Malignancies or Her2 Positive Metastatic Breast Cancer Who Have Previously Failed Trastuzumab Therapy

Bristol-Myers Squibb

NCT00803556

COMPLETED Phase 1 29 participants

Safety, Pharmacokinetics and Pharmacodynamics of BEZ235 Plus MEK162 in Selected Advanced Solid Tumor Patients

Pfizer

NCT01337765

COMPLETED Phase 2 29 participants

Eribulin and Lenvatinib in Advanced Solid Tumors

Virginia G. Kaklamani

NCT02640508

COMPLETED Phase 1 27 participants

A Phase I/II Trial of Crolibulin (EPC2407) Plus Cisplatin in Adults With Solid Tumors With a Focus on Anaplastic Thyroid Cancer (ATC)

National Cancer Institute (NCI)

NCT01240590

COMPLETED Phase 1 25 participants

Busulfan, Melphalan, Topotecan Hydrochloride, and a Stem Cell Transplant in Treating Patients With Newly Diagnosed or Relapsed Solid Tumor

City of Hope Medical Center

NCT00638898

COMPLETED Phase 1 24 participants

Sym023 (Anti-TIM-3) in Patients With Advanced Solid Tumor Malignancies or Lymphomas

Symphogen A/S

NCT03489343

COMPLETED Phase 1 24 participants

Trial Evaluating the Safety and Pharmacokinetics of MFGR1877S in Patients With Advanced Solid Tumors

Genentech

NCT01363024

COMPLETED 22 participants

Pain Control in Hospice Patients With Cancer-Related Pain

Vanderbilt-Ingram Cancer Center

NCT00609297

COMPLETED Phase 1 21 participants

Trial of Mistletoe Extract in Patients With Advanced Solid Tumors

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT03051477

COMPLETED Phase 1 19 participants

Solid Tumors Using Ixabepilone and Dasatinib

Medstar Health Research Institute

NCT00717704

COMPLETED Phase 1 18 participants

HCW9218 in Select Advanced Solid Tumors

Masonic Cancer Center, University of Minnesota

NCT05322408

COMPLETED Phase 1 14 participants

A Pharmacokinetic and Pharmacodynamic Study of DZ-002 in Patients With Advanced Solid Malignancies or Lymphoma

Da Zen Theranostics

NCT04970992

COMPLETED 14 participants

Concurrent School Attendance And Cancer Therapy: The Experiences of 6-12 Year Old Pediatric Oncology Patients

St. Jude Children's Research Hospital

NCT01383473

COMPLETED Phase 2 12 participants

Everolimus in Patients With Advanced Solid Malignancies With TSC1, TSC2, NF1, NF2, or STK11 Mutations

Washington University School of Medicine

NCT02352844

COMPLETED Phase 1 12 participants

IRX-2 Regimen Combined With Nivolumab in Recurrent/Metastatic Solid Tumors

H. Lee Moffitt Cancer Center and Research Institute

NCT03758781

COMPLETED Phase 1 11 participants

GEN-001 (Live Biotherapeutic Product) and Avelumab Combination Study for Patients With Solid Tumors Who Have Progressed on Anti-PD-(L)1 Therapy

Genome & Company

NCT04601402

COMPLETED Phase 1 10 participants

Safety of 24-hour Infusion of ON 01910.Na in Combination With Gemcitabine in Advanced Solid Tumors

Traws Pharma

NCT01165905

COMPLETED Phase 1 7 participants

TCR-engineered T Cells in Solid Tumors (ACTengine IMA201-101)

Immatics US

NCT03247309

COMPLETED Phase 2 5 participants

SBRT + PD-1/PDL-1 Inhibiting Therapy for Advanced Solid Tumors After Dz Control on PD-1/PDL-1 Tx

Virginia Commonwealth University

NCT03220854

← Previous Page 4 of 4

Phase Distribution

PhaseTrial count
Phase 1 150
Phase 2 15
Phase 3 1
Phase 4 3

Named interventions

Most-linked intervention names on Solid Tumor records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Nivolumab Drug
7 trials
Pembrolizumab Drug
5 trials
Gemcitabine Drug
4 trials
Leucovorin Drug
4 trials
Bevacizumab Drug
4 trials
Cyclophosphamide Drug
4 trials
Irinotecan Drug
3 trials
Cetuximab Drug
3 trials

US sites by state

Facility locations filed on Solid Tumor trials. A trial with sites in several states counts in each.

Texas 93 trials
California 72 trials
New York 67 trials
Florida 47 trials
Tennessee 42 trials
Massachusetts 38 trials
Michigan 36 trials
Arizona 36 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Solid Tumor page

197 registered trials, 104 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Solid Tumor condition card totals 197 registered trials; most-linked intervention Nivolumab; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.