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ClinicalTrials.gov 104 recruiting now official registry

Solid Tumor clinical trials

104 of 197 indexed Solid Tumor trials are currently recruiting.

197 US clinical trials · 104 currently recruiting

Solid Tumor is the subject of 197 registered US clinical trials on ClinicalTrials.gov, 104 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 165 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 11 of these trials.

The research picture

Solid Tumor has 197 registered US clinical trials, 104 of them open to new participants right now, about 53% of the total.

104
recruiting participants now
53%
of trials open to enrollment
4
in Phase 3–4 (later-stage)
11
top sponsor: Memorial Sloan Kettering Cancer Center
Phase 1150Phase 215Phase 31Phase 43

Active & Recent Trials

197 total, page 4 of 4

COMPLETED NA 279 participants

Illness Management and Parental Adjustment to Cancer Treatment

Children's Hospital Medical Center, Cincinnati

NCT02505165

COMPLETED 252 participants

Validating Pain Scales in Children and Young Adults

National Cancer Institute (NCI)

NCT01639950

COMPLETED Phase 1 174 participants

A Study of Evorpacept (ALX148) in Patients With Advanced Solid Tumors and Lymphoma (ASPEN-01)

ALX Oncology

NCT03013218

COMPLETED Phase 1 164 participants

A Study of Anti-PD-L1 Checkpoint Antibody (LY3300054) Alone and in Combination in Participants With Advanced Refractory Solid Tumors

Eli Lilly and Company

NCT02791334

COMPLETED Phase 4 163 participants

Durvalumab Long-Term Safety and Efficacy Study

AstraZeneca

NCT04078152

COMPLETED Phase 1 127 participants

Dose-Finding and Safety Study for Oral Single-Agent to Treat Advanced Malignancies

Processa Pharmaceuticals

NCT02030067

COMPLETED Phase 1 119 participants

Phase 1/2 Study of Derazantinib (ARQ 087) in Adult Subjects With Advanced Solid Tumors With FGFR Genetic Alterations

Basilea Pharmaceutica

NCT01752920

COMPLETED Phase 1 114 participants

Study of Mogamulizumab + Nivolumab in Subjects w/Locally Advanced or Metastatic Solid Tumors

Kyowa Kirin

NCT02705105

COMPLETED NA 92 participants

Individualized Stereotactic Body Radiotherapy of Liver Metastases

Massachusetts General Hospital

NCT01239381

COMPLETED Phase 1 89 participants

Sym021 Monotherapy, in Combination With Sym022 or Sym023, and in Combination With Both Sym022 and Sym023 in Patients With Advanced Solid Tumor Malignancies or Lymphomas

Symphogen A/S

NCT03311412

COMPLETED Phase 1 88 participants

Phase 1 Trial of Hu5F9-G4, a CD47-targeting Antibody

Gilead Sciences

NCT02216409

COMPLETED Phase 1 80 participants

A Study of of MORAb-004 in Subjects With Solid Tumors

Morphotek

NCT00847054

COMPLETED Phase 1 78 participants

A Phase 1a/b Study of IK-175 as a Single Agent and in Combination With Nivolumab in Patients With Locally Advanced or Metastatic Solid Tumors and Urothelial Carcinoma

Ikena Oncology

NCT04200963

COMPLETED Phase 2 76 participants

A Study to Assess the Potential Effects of a Single-Dose Administration of Trabectedin on the QT Intervals of the Electrocardiogram

Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

NCT00786838

COMPLETED Phase 1 73 participants

A Dose Escalation Study of Radio-labeled Antibody for the Treatment of Advanced Cancer

Fujifilm Pharmaceuticals U.S.A.

NCT02454010

COMPLETED Phase 1 68 participants

Safety, Pharmacokinetics and Clinical Activity of Oral Rigosertib in Solid Tumors

Traws Pharma

NCT01168011

COMPLETED Phase 1 60 participants

A Phase I Dose-Escalation Study of IMGN388 in Patients With Solid Tumors

ImmunoGen

NCT00721669

COMPLETED Phase 1 57 participants

AO-176 in Multiple Solid Tumor Malignancies

Arch Oncology

NCT03834948

COMPLETED Phase 1 54 participants

Capecitabine or 5-Fluorouracil in Combination With Irinotecan and Cisplatin in Patients With Solid Tumor Malignancies

Dana-Farber Cancer Institute

NCT00215501

COMPLETED Phase 1 50 participants

CB-839 + Capecitabine in Solid Tumors and Fluoropyrimidine Resistant PIK3CA Mutant Colorectal Cancer

David Bajor, MD

NCT02861300

COMPLETED Phase 1 48 participants

Indocyanine Green for Solid Tumors

University of Pennsylvania

NCT02280954

COMPLETED Phase 1 46 participants

Study to Assess Safety and Efficacy of the Second Mitochondrial-derived Activator of Caspases (SMAC) Mimetic Debio 1143

Debiopharm International

NCT04122625

COMPLETED Phase 1 46 participants

Study of an Investigational Drug, ASP3026, in Patients With Advanced Malignancies (Solid Tumors and B-Cell Lymphoma)

Astellas Pharma

NCT01284192

COMPLETED Phase 1 45 participants

A Phase 1 Study to Investigate Axatilimab Alone or in Combination With Durvalumab in Patients With Solid Tumors

Syndax Pharmaceuticals

NCT03238027

COMPLETED Phase 1 44 participants

LYT-200 Alone and in Combination With Chemotherapy or Tislelizumab in Patients With Locally Advanced or Metastatic Solid Tumors

PureTech

NCT04666688

COMPLETED 43 participants

The Good Patient Study

St. Jude Children's Research Hospital

NCT02199548

COMPLETED Phase 1 38 participants

A Study to Evaluate the Safety, Tolerability, MTD, PK, and Activity of Oraxol in Subjects w Adv. Malignancies

Athenex

NCT02730481

COMPLETED 31 participants

Immune Reconstitution in Oncology Patients Following Autologous Stem Cell Transplant

St. Jude Children's Research Hospital

NCT01540175

COMPLETED Phase 1 29 participants

Clinical Trial of the Combination of Intravenous Alvespimycin (KOS-1022), Trastuzumab With or Without Paclitaxel in Patients With Advanced Solid Tumor Malignancies or Her2 Positive Metastatic Breast Cancer Who Have Previously Failed Trastuzumab Therapy

Bristol-Myers Squibb

NCT00803556

COMPLETED Phase 1 29 participants

Safety, Pharmacokinetics and Pharmacodynamics of BEZ235 Plus MEK162 in Selected Advanced Solid Tumor Patients

Pfizer

NCT01337765

COMPLETED Phase 2 29 participants

Eribulin and Lenvatinib in Advanced Solid Tumors

Virginia G. Kaklamani

NCT02640508

COMPLETED Phase 1 27 participants

A Phase I/II Trial of Crolibulin (EPC2407) Plus Cisplatin in Adults With Solid Tumors With a Focus on Anaplastic Thyroid Cancer (ATC)

National Cancer Institute (NCI)

NCT01240590

COMPLETED Phase 1 25 participants

Busulfan, Melphalan, Topotecan Hydrochloride, and a Stem Cell Transplant in Treating Patients With Newly Diagnosed or Relapsed Solid Tumor

City of Hope Medical Center

NCT00638898

COMPLETED Phase 1 24 participants

Sym023 (Anti-TIM-3) in Patients With Advanced Solid Tumor Malignancies or Lymphomas

Symphogen A/S

NCT03489343

COMPLETED Phase 1 24 participants

Trial Evaluating the Safety and Pharmacokinetics of MFGR1877S in Patients With Advanced Solid Tumors

Genentech

NCT01363024

COMPLETED 22 participants

Pain Control in Hospice Patients With Cancer-Related Pain

Vanderbilt-Ingram Cancer Center

NCT00609297

COMPLETED Phase 1 21 participants

Trial of Mistletoe Extract in Patients With Advanced Solid Tumors

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT03051477

COMPLETED Phase 1 19 participants

Solid Tumors Using Ixabepilone and Dasatinib

Medstar Health Research Institute

NCT00717704

COMPLETED Phase 1 18 participants

HCW9218 in Select Advanced Solid Tumors

Masonic Cancer Center, University of Minnesota

NCT05322408

COMPLETED Phase 1 14 participants

A Pharmacokinetic and Pharmacodynamic Study of DZ-002 in Patients With Advanced Solid Malignancies or Lymphoma

Da Zen Theranostics

NCT04970992

COMPLETED 14 participants

Concurrent School Attendance And Cancer Therapy: The Experiences of 6-12 Year Old Pediatric Oncology Patients

St. Jude Children's Research Hospital

NCT01383473

COMPLETED Phase 2 12 participants

Everolimus in Patients With Advanced Solid Malignancies With TSC1, TSC2, NF1, NF2, or STK11 Mutations

Washington University School of Medicine

NCT02352844

COMPLETED Phase 1 12 participants

IRX-2 Regimen Combined With Nivolumab in Recurrent/Metastatic Solid Tumors

H. Lee Moffitt Cancer Center and Research Institute

NCT03758781

COMPLETED Phase 1 11 participants

GEN-001 (Live Biotherapeutic Product) and Avelumab Combination Study for Patients With Solid Tumors Who Have Progressed on Anti-PD-(L)1 Therapy

Genome & Company

NCT04601402

COMPLETED Phase 1 10 participants

Safety of 24-hour Infusion of ON 01910.Na in Combination With Gemcitabine in Advanced Solid Tumors

Traws Pharma

NCT01165905

COMPLETED Phase 1 7 participants

TCR-engineered T Cells in Solid Tumors (ACTengine IMA201-101)

Immatics US

NCT03247309

COMPLETED Phase 2 5 participants

SBRT + PD-1/PDL-1 Inhibiting Therapy for Advanced Solid Tumors After Dz Control on PD-1/PDL-1 Tx

Virginia Commonwealth University

NCT03220854

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Phase Distribution

PhaseTrial count
Phase 1 150
Phase 2 15
Phase 3 1
Phase 4 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Solid Tumor Trial Landscape

197 indexed Solid Tumor studies · 104 recruiting (53%).

Phase mix: 4 late (III/IV) vs 165 early (I/II).

Top sponsor: Memorial Sloan Kettering Cancer Center (11 trials), 9 others listed. 47 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Solid Tumor?

PlainTrial tracks 197 US clinical trials for Solid Tumor, of which 104 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Solid Tumor?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.