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ACTIVE NOT RECRUITING Phase 1

A Phase 1/2a Study of 23ME-00610 in Patients With Advanced Solid Malignancies

NCT05199272 · View on ClinicalTrials.gov ↗

Study Summary

This is a first-in-human open-label Phase 1/2a study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary clinical activity of 23ME-00610 given by intravenous infusion in patients with advanced solid malignancies who have progressed on all available standard therapies

Interventions

  • DRUG 23ME-00610

Study Locations (13)

Ontario

  • Ottawa Hospital Cancer Centre — Ottawa
  • Princess Margaret Cancer Centre — Toronto
  • The Hospital for Sick Children — Toronto

New York

  • R.J.Zuckerberg Cancer Center — Lake Success
  • Cohen Children's Medical Center — New Hyde Park

Texas

  • MD Anderson Cancer Center — Houston
  • START Center for Cancer Care — San Antonio

California

  • Stanford Cancer Institute — Palo Alto

Georgia

  • Emory University — Atlanta

Michigan

  • Karmanos Cancer Institute — Detroit

Oregon

  • Oregon Health & Science University — Portland

Tennessee

  • Vanderbilt University — Nashville

Trial Details

FieldValue
Enrollment Target 141 participants
Start Date 2021-12-29
Est. Completion 2025-03
Phase Phase 1

Sponsor

23andMe

3 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05199272

The ClinicalTrials.gov registry entry for NCT05199272 describes a study currently listed as active not recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 141 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is 23andMe, which has 3 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 9 conditions, with Solid Tumor appearing as the primary indexed condition, and to 1 intervention — of which 23ME-00610 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05199272 reports 13 study locations spanning 9 distinct geographic areas — top geographies include Ontario, New York, Texas. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05199272 about?

NCT05199272 is a clinical study titled "A Phase 1/2a Study of 23ME-00610 in Patients With Advanced Solid Malignancies". This is a first-in-human open-label Phase 1/2a study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary clinical activity of 23ME-00610 given by intravenous infusion in patients with advanced solid malignancies who have progressed on all available standard ther...

What is the current status of trial NCT05199272?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 141 participants. The study started on 2021-12-29. Estimated completion is 2025-03.

What conditions does trial NCT05199272 study?

This clinical trial studies the following conditions: Solid Tumor, Fallopian Tube Cancer, Neuroendocrine Tumors, Clear Cell Renal Cell Carcinoma, Epithelial Ovarian Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05199272?

The interventions under investigation include: 23ME-00610 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05199272?

This trial is sponsored by 23andMe, which has 3 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05199272 being conducted?

This trial has 13 study locations across California, Georgia, Michigan, New York, Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial