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NCT05566574 · ClinicalTrials.gov registry record · Phase 1
A Study of RP-3500 in Combination With Standard Radiation Therapy in People With Solid Tumor Cancer
A Phase 1 study of Solid Tumor and Metastatic Cancer, sponsored by Memorial Sloan Kettering Cancer Center.
- Active
- Registry status
- Phase 1
- Development phase
- 49
- Enrollment target
- 7
- Study locations
NCT05566574 is a Phase 1 study of Solid Tumor and Metastatic Cancer that is active but no longer recruiting, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 49 participants, below the 221-participant average among 196 other Solid Tumor trials with a reported enrollment target (78% lower). The trial reports 7 study locations across 2 states.
The verdict
NCT05566574, a Phase 1 study of Solid Tumor and Metastatic Cancer, is active but no longer recruiting, sponsored by Memorial Sloan Kettering Cancer Center.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 49 participants
- Enrollment target
- 7
- Study locations
Study Summary
The purpose of this study is to test the safety of the study drug, RP-3500 when given in combination with palliative external beam radiotherapy (EBRT) to people who have metastatic solid tumor cancer with a mutation of the ATM gene. The study researchers will do tests to find the highest dose of RP3500 that causes few or mild side effects.
Conditions Studied
Interventions
- RADIATION External Beam Radiotherapy (EBRT)
- DRUG RP-3500
Study Locations (7)
New York
- Memorial Sloan Kettering Cancer Center at Suffolk-Commack (All Protocol Activities) - Commack
- Memorial Sloan Kettering Westchester (All Protocol Activities) - Harrison
- Memorial Sloan Kettering Cancer Center (All Protocol Activities) - New York
- Memorial Sloan Kettering Nassau (Limited Protocol Activities) - Uniondale
New Jersey
- Memorial Sloan Kettering Basking Ridge (Limited Protocol Activites) - Basking Ridge
- Memorial Sloan Kettering Monmouth (All Protocol Activities) - Middletown
- Memorial Sloan Kettering Bergen (Limited Protocol Activities) - Montvale
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 49 participants |
| Start Date | 2022-09-30 |
| Est. Completion | 2026-09-30 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05566574
The ClinicalTrials.gov registry entry for NCT05566574 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 49 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 221-participant average among 196 other Solid Tumor trials with a reported enrollment target (78% lower). The listed sponsor is Memorial Sloan Kettering Cancer Center, which has 1,884 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Solid Tumor appearing as the primary indexed condition, and to 2 interventions - of which External Beam Radiotherapy (EBRT) is the first listed.
NCT05566574 reports 7 study locations spanning 2 distinct geographic areas - top geographies include New York, New Jersey.
Frequently Asked Questions
What is clinical trial NCT05566574 about?
NCT05566574 is a clinical study titled "A Study of RP-3500 in Combination With Standard Radiation Therapy in People With Solid Tumor Cancer". The purpose of this study is to test the safety of the study drug, RP-3500 when given in combination with palliative external beam radiotherapy (EBRT) to people who have metastatic solid tumor cancer with a mutation of the ATM gene. The study researchers will do tests to find the highest dose of RP3...
What is the current status of trial NCT05566574?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 49 participants. The study started on 2022-09-30. Estimated completion is 2026-09-30.
What conditions does trial NCT05566574 study?
This clinical trial studies the following conditions: Solid Tumor, Metastatic Cancer.
What interventions are being tested in trial NCT05566574?
The interventions under investigation include: External Beam Radiotherapy (EBRT) (RADIATION), RP-3500 (DRUG).
Who is sponsoring clinical trial NCT05566574?
This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05566574 being conducted?
This trial has 7 study locations across New Jersey, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.