Astellas Pharma

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Astellas Pharma sits in the top decile of US sponsors by registered trial count (#179 of 15,742 sponsors by registered trial count).

165 total trials 2 currently recruiting 143 completed early-phase tilt top decile by trial count

Astellas Pharma: 165 sponsored US clinical trials, 2 recruiting.

Astellas Pharma sponsors 165 registered US clinical trials on ClinicalTrials.gov, 2 of them currently recruiting, and 143 completed. 47 of these trials are in Phase 3-4 (later-stage) and 113 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Candidemia, with 4 trials.

Top-decile sponsor footprint

Astellas Pharma ranks in the top decile of sponsors by registered trial count (#179 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 60/100

143 of 162 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.3%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

165 total, page 1 of 4

RECRUITING Phase 1

A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors

NCT07094204

RECRUITING Phase 1

A Study of ASP3082 in Adults With Advanced Solid Tumors

NCT05382559

ACTIVE NOT RECRUITING Phase 1

A Study to Find a Suitable Dose of ASP4396 in Adults With Solid Tumors

NCT06364696

TERMINATED Phase 2

A Study to Find the Best Dose of ASP5354 to Show Lymph Nodes in People With Breast Cancer or Melanoma During Surgery

NCT05457842

TERMINATED Phase 2

A Study to Evaluate ASP0367 in Participants With Primary Mitochondrial Myopathy

NCT04641962

TERMINATED Phase 1

A Study to Assess the Safety, Tolerability and Preliminary Efficacy of ASP0367 (MA-0211) in Pediatric Male Participants With Duchenne Muscular Dystrophy (DMD)

NCT04184882

COMPLETED Phase 2

A Study for Ureter Visualization, Using ASP5354 in Subjects Undergoing Laparoscopic/Minimally Invasive Colorectal Surgery

NCT04238481

COMPLETED Phase 2

Study to Evaluate the Efficacy of ASP1128 (MA-0217) in Subjects at Risk for Acute Kidney Injury (AKI) Following Coronary Artery Bypass Graft (CABG) and/or Valve Surgery

NCT03941483

COMPLETED Phase 2

A Study of Enfortumab Vedotin for Patients With Locally Advanced or Metastatic Urothelial Bladder Cancer

NCT03219333

COMPLETED Phase 1

An Open-label Phase I Study of Orally Available Novel Small-molecule Fibroblast Growth Factor Receptors (FGFR) 1,2,3 and 4 Inhibitor, ASP5878 at Single and Multiple Doses in Patients With Solid Tumors

NCT02038673

COMPLETED Phase 2

A Study to Evaluate the Safety and Efficacy of ASP015K in Moderate to Severe Rheumatoid Arthritis Subjects Who Have Had an Inadequate Response to Methotrexate

NCT01554696

COMPLETED Phase 3

A Study to Evaluate Efficacy and Safety of a Single Application of Capsaicin 8%Transdermal Delivery System Compared to Placebo in Reducing Pain Intensity in Subjects With Painful Diabetic Peripheral Neuropathy (PDPN)

NCT01533428

COMPLETED Phase 1

Drug Interaction Study of Isavuconazole and Tacrolimus

NCT01535547

TERMINATED Phase 2

A Study to Evaluate the Effect of ASP8597 in Adult Kidney Transplant Patients

NCT01442337

COMPLETED Phase 1

Drug Interaction Study of Isavuconazole and Cyclosporine

NCT01494597

COMPLETED Phase 2

A Study to Assess the Safety of Continued Administration of MDV3100 in Subjects With Prostate Cancer Who Showed Benefit From Prior Exposure to MDV3100

NCT01534052

COMPLETED Phase 1

A Single Oral Dose Study to Compare the Bioavailability Between Two Different Tablet Formulations and Assess if There is a Food Effect With the New Formulation

NCT01484964

COMPLETED Phase 1

A Single Oral Dose Study of ASP015K in Healthy Volunteers Assessing the Relative Bioavailability Across Three Tablet Strengths From a New Formulation of ASP015K

NCT01486017

COMPLETED Phase 4

A Study to Assess Efficacy and Safety With Solifenacin Succinate to Improve Urinary Continence After Robotic Assisted Radical Prostatectomy

NCT01371994

COMPLETED Phase 1

A Study of the Safety and Pharmacokinetics of AGS-22M6E in Subjects With Malignant Solid Tumors That Express Nectin-4

NCT01409135

COMPLETED Phase 1

A Study of the Safety and Tolerability of ASP0777 in Subjects With Alzheimer's Disease (AD) Taking a Stable Dose of Donepezil

NCT01406145

COMPLETED Phase 1

Drug Interaction Study of Isavuconazole and Midazolam

NCT01406171

COMPLETED Phase 1

A Study in Healthy Volunteers Comparing Two Different Liquid Formulations of Solifenacin With Each Other and With the Tablet Formulation

NCT01406158

COMPLETED Phase 2

A Study of Regadenoson in Subjects Undergoing Stress Myocardial Perfusion Imaging (MPI) Using Multidetector Computed Tomography (MDCT) Compared to Single Photon Emission Computed Tomography (SPECT)

NCT01334918

COMPLETED Phase 2

Study of Erlotinib (Tarceva®) in Combination With OSI-906 in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) With Activating Mutations of the Epidermal Growth Factor Receptor (EGFR) Gene

NCT01221077

COMPLETED Phase 2

A Study of Enzalutamide Versus Bicalutamide in Castrate Men With Metastatic Prostate Cancer

NCT01288911

COMPLETED Phase 2

Phase 2 Study of Maintenance OSI-906 Plus Erlotinib (Tarceva®), or Placebo Plus Erlotinib in Patients With Nonprogression Following 4 Cycles of Platinum-based Chemotherapy

NCT01186861

COMPLETED

A Study to Assess the Receptor Occupancy of CD86 and CD80 in Subjects With Rheumatoid Arthritis Initiating Abatacept

NCT01339481

TERMINATED Phase 2

A Randomized, Placebo-controlled, Double-blind Phase 2 Study With OSI-906 in Patients With Advanced HCC

NCT01101906

COMPLETED Phase 1

Study of an Investigational Drug, ASP3026, in Patients With Advanced Malignancies (Solid Tumors and B-Cell Lymphoma)

NCT01284192

COMPLETED Phase 1

A Study to Assess Pharmacokinetic, Pharmacodynamic, Safety and Tolerability of ASKP1240 in de Novo Kidney Transplantation

NCT01279538

COMPLETED Phase 1

A Study to Assess Intraocular Pressure and Ocular Safety of the Beta-3 Agonist Mirabegron in Research Subjects

NCT01284309

COMPLETED Phase 1

A Study to Determine the Maximum Tolerated Dose of ASG-5ME in Subjects With Castration-Resistant Prostate Cancer

NCT01228760

COMPLETED Phase 1

A Study of the Effect of ASP1941 on Cardiac Repolarization in Healthy Subjects

NCT01232413

COMPLETED Phase 1

A First in Man Study to Determine the Safety at Various Dose Levels of AGS-16M8F in Advanced Kidney Cancer

NCT01114230

COMPLETED Phase 1

A Study to Evaluate the Drug Interaction of ASP015K and Tacrolimus

NCT01190670

TERMINATED

A Pilot Trial in a Sleep Laboratory Setting to Observe Night Time Bladder Function of Subjects With Overactive Bladder (OAB)

NCT01099345

COMPLETED Phase 1

A Study to Assess Drug Interaction of ASP015K and Midazolam

NCT01182077

COMPLETED Phase 1

A Study to Evaluate the Effect of Oral Mirabegron on the Heart in Healthy Males and Females

NCT01199523

COMPLETED Phase 1

A Study to Assess the Effect of Hepatic Function on the Pharmacokinetics and Safety of ASP1941

NCT01187186

COMPLETED Phase 2

A Study to Evaluate the Effect of ASP1941 in Combination With Metformin in Adult Patients With Type 2 Diabetes Mellitus

NCT01117584

COMPLETED Phase 1

A Study to Assess the Systemic Disposition of ASP1585 After Administration of 14C-labeled Drug

NCT01124747

COMPLETED Phase 2

A Study to Explore Efficacy and Safety of ASP015K in Subjects With Moderate to Severe Psoriasis

NCT01096862

COMPLETED Phase 2

A Study to Evaluate the Effect of ASP1941 in Adult Patients With Type 2 Diabetes Mellitus

NCT01071850

COMPLETED Phase 1

A Study to Characterize the Effect on the Pharmacokinetics of ASP1941 and Sitagliptin When Given Together to Healthy Subjects

NCT01104532

COMPLETED Phase 1

A Drug Interaction Study to Evaluate the Pharmacokinetics of ASP015K and Methotrexate in Patients With Rheumatoid Arthritis

NCT01754805

COMPLETED Phase 4

Study of 2 Doses of Solifenacin Succinate in Female Subjects With Overactive Bladder.

NCT01093534

COMPLETED Phase 3

A Study of OSI-906 in Patients With Locally Advanced or Metastatic Adrenocortical Carcinoma

NCT00924989

COMPLETED Phase 2

A Study of YM155 Plus Docetaxel as First-Line Treatment in Subjects With HER2 Negative Metastatic Breast Cancer

NCT01038804

COMPLETED Phase 1

A Study to Assess the Pharmacokinetics of ASP015K in Healthy Male Subjects

NCT01406132

Page 1 of 4 Next →

Phase Distribution

PhaseTrial count
Phase 1 59
Phase 2 54
Phase 3 28
Phase 4 19

What is open in the Astellas Pharma pipeline

2 recruiting of 165 indexed (1% open); 143 completed (87%).

Phase mix: 47 late (III/IV) vs 113 early (I/II) (early-phase heavy).

Top condition: Candidemia (4 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Astellas Pharma: open-pipeline peers nationwide

Peers matched on 165 registered trials and 1% open enrollment, not the therapeutic-area sidebar.

Astellas Pharma sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 50100150200 0%5%10%15% Total trials Recruiting share Astellas PharmaTeva Branded Pharmaceutical Products R&DWyeth is now a wholly owned subsidiary of PfizerTemple UniversityTufts UniversityUniversity of New MexicoAbbott NutritionBaxalta now part of ShirePower Life Sciences
Astellas Pharma sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Astellas Pharma sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 165 trials (± recruiting share)

Sponsors near 1% open enrollment (± trial volume)

What to do with this Astellas Pharma page

165 registered trials is a research-attention snapshot, not an endorsement of Astellas Pharma or any single study.

  • 2 of Astellas Pharma's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Candidemia is the condition Astellas Pharma studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Candidemia trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Astellas Pharma pipeline card: 165 registered trials from official public datasets.Report a data error.