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ACTIVE NOT RECRUITING

MRD Assay Evaluates Recurrence and Response Via a Tumor Informed Assessment

NCT05219734 · View on ClinicalTrials.gov ↗

Study Summary

This study recruits patient with solid tumor types for sample collection and monitoring. Participants will provide blood and archival tissue samples in order to create a Personalized Cancer Monitoring (PCM) assay. This assay will be used to detect circulating tumor DNA (ctDNA) levels in the blood over time and hopefully contribute to improvements in residual disease detection methods for future patients. Results from this assay will be provided to participants and providers but providers are not asked to change patient care based on this information.

Interventions

  • DIAGNOSTIC_TEST Personalized Cancer Monitoring (PCM)

Study Locations (2)

Indiana

  • Columbus Regional Health — Columbus

North Carolina

  • Onslow Radiation — Jacksonville

Trial Details

FieldValue
Enrollment Target 400 participants
Start Date 2021-11-29
Est. Completion 2026-12

Sponsor

Invitae Corporation

1 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05219734

The ClinicalTrials.gov registry entry for NCT05219734 describes a study currently listed as active not recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 400 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Invitae Corporation, which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 5 conditions, with Cancer appearing as the primary indexed condition, and to 1 intervention — of which Personalized Cancer Monitoring (PCM) is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05219734 reports 2 study locations spanning 2 distinct geographic areas — top geographies include Indiana, North Carolina. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05219734 about?

NCT05219734 is a clinical study titled "MRD Assay Evaluates Recurrence and Response Via a Tumor Informed Assessment". This study recruits patient with solid tumor types for sample collection and monitoring. Participants will provide blood and archival tissue samples in order to create a Personalized Cancer Monitoring (PCM) assay. This assay will be used to detect circulating tumor DNA (ctDNA) levels in the blood ov...

What is the current status of trial NCT05219734?

This trial is currently active not recruiting. The enrollment target is 400 participants. The study started on 2021-11-29. Estimated completion is 2026-12.

What conditions does trial NCT05219734 study?

This clinical trial studies the following conditions: Cancer, Colorectal Cancer, Solid Tumor, Bladder Cancer, Non Small Cell Lung Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05219734?

The interventions under investigation include: Personalized Cancer Monitoring (PCM) (DIAGNOSTIC_TEST). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05219734?

This trial is sponsored by Invitae Corporation, which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05219734 being conducted?

This trial has 2 study locations across Indiana, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial