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NCT06894745 · ClinicalTrials.gov registry record · Phase 1

PET [89Zr]DFO-starPEG in Solid Tumors

A Phase 1 study of Solid Tumor and Solid Carcinoma, sponsored by Robert Flavell, MD, PhD.

Recruiting
Registry status
Phase 1
Development phase
13
Enrollment target
1
Study location

NCT06894745 is a Phase 1 study of Solid Tumor and Solid Carcinoma that is actively recruiting participants, run by Robert Flavell, MD, PhD. The registered enrollment target is 13 participants, below the 222-participant average among 196 other Solid Tumor trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06894745, a Phase 1 study of Solid Tumor and Solid Carcinoma, is actively recruiting participants, sponsored by Robert Flavell, MD, PhD.

RECRUITING
Registry status
Phase 1
Development phase
13 participants
Enrollment target
1
Study location

Study Summary

This is a first-in-human, pilot study of the novel PET-imaging radiotracer \[89Zr\]DFO-starPEG. The study is designed to obtain preliminary data to support future development of this agent as an imaging surrogate to visualize enhanced permeability and retention (EPR)-mediated tracer uptake before administration of EPR-based nanomedicines.

Interventions

  • PROCEDURE Specimen Collection
  • DRUG 89-zr-dfo-star polyethylene glycol (StarPEG)
  • PROCEDURE Whole Body Positron Emission Tomography (PET)

Study Locations (1)

California

  • University of California, San Francisco - San Francisco

Trial Details

FieldValue
Enrollment Target 13 participants
Start Date 2025-06-02
Est. Completion 2027-12-31
Phase Phase 1

Sponsor

Robert Flavell, MD, PhD

5 total trials

What the Registry Record Tells You About NCT06894745

The ClinicalTrials.gov registry entry for NCT06894745 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 13 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 222-participant average among 196 other Solid Tumor trials with a reported enrollment target (94% lower). The listed sponsor is Robert Flavell, MD, PhD, which has 5 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Solid Tumor appearing as the primary indexed condition, and to 3 interventions - of which Specimen Collection is the first listed.

NCT06894745 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT06894745 about?

NCT06894745 is a clinical study titled "PET [89Zr]DFO-starPEG in Solid Tumors". This is a first-in-human, pilot study of the novel PET-imaging radiotracer \[89Zr\]DFO-starPEG. The study is designed to obtain preliminary data to support future development of this agent as an imaging surrogate to visualize enhanced permeability and retention (EPR)-mediated tracer uptake before ad...

What is the current status of trial NCT06894745?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 13 participants. The study started on 2025-06-02. Estimated completion is 2027-12-31.

What conditions does trial NCT06894745 study?

This clinical trial studies the following conditions: Solid Tumor, Solid Carcinoma, Soft Tissue Lesion.

What interventions are being tested in trial NCT06894745?

The interventions under investigation include: Specimen Collection (PROCEDURE), 89-zr-dfo-star polyethylene glycol (StarPEG) (DRUG), Whole Body Positron Emission Tomography (PET) (PROCEDURE).

Who is sponsoring clinical trial NCT06894745?

This trial is sponsored by Robert Flavell, MD, PhD, which has 5 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06894745 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.