Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

523 total trials 69 currently recruiting 301 completed

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins sponsors 523 registered US clinical trials on ClinicalTrials.gov, 69 of them currently recruiting, and 301 completed. 5 of these trials are in Phase 3-4 (later-stage) and 395 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Prostate Cancer, with 17 trials.

Trial Pipeline

523 total, page 1 of 11

RECRUITING Phase 1

DK222 Study at Hopkins

NCT07140315

RECRUITING Phase 2

Capecitabine/Oxaliplatin Chemotherapy and Cemiplimab With or Without Fianlimab or REGN7075 in Locally Advanced Rectal Cancer

NCT07281768

RECRUITING Phase 2

Assessing Administration of pBI-11 Via Electroporation for the Treatment of Patients With HPV16/18+

NCT06210854

RECRUITING NA

Music Therapy in Newly Diagnosed Glioblastoma After Chemoradiation Therapy (MELODY-GBM)

NCT07375992

RECRUITING NA

Precision Radiotherapy Enabled by Molecular MRI

NCT07512154

RECRUITING Early Phase 1

Momelotinib in Combination With Hypomethylating Agent for Chronic Phase Myelodysplastic Syndromes/Myeloproliferative Overlap Neoplasms and Chronic Neutrophilic Leukemia

NCT07071155

RECRUITING Phase 2

Supraphysiologic Testosterone Priming Induces Darolutamide Extended Response

NCT07142551

RECRUITING Phase 2

Neoadjuvant Chemotherapy and Programmed Cell Death Protein 1(PD-1) Inhibition for Head and Neck Cancer Treatment De-escalation (NeoScorch HN)

NCT07209189

RECRUITING NA

Physician- and Patient-based Barriers to NGS Testing

NCT07209176

RECRUITING NA

Patient Navigation Program to Improve Clinical Trial Enrollment in Cancer Patients

NCT06138067

RECRUITING

Pediatric Radiation Therapy Registry

NCT07129317

RECRUITING NA

Exercise in Prostate Cancer

NCT06165302

RECRUITING Phase 1

A Clinical Trial to Assess PVX7 Immunotherapy Regimens in Advanced Cervical Cancer Patients

NCT06315257

RECRUITING Phase 2

NC410 and FOLFIRINOX in Combination With Nivolumab With or Without Ipilimumab in Patients With Untreated Metastatic Pancreatic Cancer

NCT06941857

RECRUITING Phase 2

The COSMYC Trial (COmbined Suppression of MYC)

NCT06922318

RECRUITING Phase 1

KRAS-Targeted Vaccine Combined With Balstilimab and Botensilimab for Patients With Stage IV MMR-p Colorectal Cancer and Pancreatic Ductal Cancer

NCT06411691

RECRUITING NA

7-Days Water-Only Fasting Trial in Prostate Cancer

NCT06826924

RECRUITING Phase 1

Targeting Driver Oncogenes With a Peptide Vaccine Plus Durvalumab and Tremelimumab for Patients With Biliary Tract Cancers (BTC)

NCT06564623

RECRUITING Phase 1

Comparing Neoadjuvant/Adjuvant GVAX vs a mKRASvax Given With Anti-PD-1 and Anti-CD137 for Surgically Resectable Pancreatic Cancer

NCT06782932

RECRUITING NA

Proton SBRT for Spinal Metastasis

NCT06895564

RECRUITING Early Phase 1

Feasibility of CSF and Plasma ctDNA in BRAF-altered Glioma During Treatment With Plixorafenib

NCT06610682

RECRUITING NA

Standard-of-Care Reduced-Intensity Conditioning (RIC) With 200 Versus 400 cGy of Total Body Irradiation (TBI) in Patients With Acute Leukemia Undergoing First Allogeneic Blood or Marrow Transplantation (BMT)

NCT06803745

RECRUITING NA

Targeted Oligometastatic Radiation in Pediatric and Young Adult Patients With Soft Tissue and Bone Sarcoma

NCT06796543

RECRUITING Phase 2

Stereotactic Body Proton Therapy for Treatment of Primary Renal Cell Carcinoma

NCT06376669

RECRUITING Phase 2

Trial Targeting Gut Bacterial Androgen Production to Reverse Therapeutic Resistance to Abiraterone in Patients With Metastatic Prostate Cancer

NCT06616597

RECRUITING Phase 2

Study of Senaparib in Combination With Temozolomide in ARID1A Mutation Associated Ovarian Cancer

NCT06617923

RECRUITING

SPECT Imaging for Pharmacokinetics and dosimEtry Towards TREATment Optimization

NCT06389097

RECRUITING

Study in Patients With Breast Cancer Leptomeningeal Metastasis

NCT06638294

RECRUITING Phase 2

Renal Retention in High Grade Upper Tract Urothelial Cancer

NCT05656235

RECRUITING Early Phase 1

Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies

NCT06398457

RECRUITING NA

Gut Microbiome, Adverse Effects, and Markers Through MEtabolic Reprogramming

NCT06536881

RECRUITING Phase 2

Perioperative Gemcitabine, Cisplatin, and Pembrolizumab in Potentially Resectable Biliary Tract Cancers

NCT06001658

RECRUITING NA

Behavioral Weight Loss for Cancer Survivors in Maryland: A Trial With Adaptive Interventions

NCT06463249

RECRUITING

Exploration of Personalized Biomarkers During Neoadjuvant Radiation Therapy for Spinal and Sacral Chordoma

NCT06463262

RECRUITING Phase 2

Cemiplimab With or Without Fianlimab to Treat Older Patients With Localized or Locally Advanced MSI-H Colorectal Cancer

NCT06205836

RECRUITING Phase 1

Peptide Vaccine To Prevent Acquired Resistance In Patients With Advanced ALK+ NSCLC

NCT05950139

RECRUITING Phase 2

PET Dynamics to Response-Adapted Neoadjuvant Therapy in TNBC

NCT06245889

RECRUITING NA

Pre-operative Hypofractionated Proton Therapy

NCT05917301

RECRUITING Phase 2

Trial of Neoadjuvant Enoblituzumab vs SOC in Men With High-Risk Localized Prostate Cancer

NCT06014255

RECRUITING Phase 1

DRP-104 (Glutamine Antagonist) in Combination With Durvalumab in Patients With Advanced Stage Fibrolamellar Carcinoma (FLC)

NCT06027086

RECRUITING Phase 2

Neoadjuvant Pembrolizumab and IO102-103 for Squamous Cell Carcinoma of the Head and Neck (SCCHN).

NCT05977907

RECRUITING Phase 1

Safety and Efficacy of Allogeneic HPV-specific T Cells in Adults With Recurrent or Metastatic HPV16+ Cancers

NCT04713046

RECRUITING Phase 2

Difluoromethylornithine and High Dose Testosterone With Enzalutamide in Metastatic Castration-Resistant Prostate Cancer

NCT06059118

RECRUITING Early Phase 1

Image-guided Focal Brachytherapy Utilizing Combined 18F-DCFPyl PET/CT

NCT03861676

RECRUITING NA

Cognitive Outcomes After Brain Substructure-informed Radiation Planning in Pediatric Patients

NCT05658731

RECRUITING

Liquid Biopsy-informed Precision Oncology Study to Evaluate Utility of Plasma Genomic Profiling for Therapy Selection

NCT05585684

RECRUITING Phase 1

KRAS-Targeted Vaccine With Nivolumab and Ipilimumab for Patients With NSCLC

NCT05254184

RECRUITING Phase 1

Carmustine Wafer in Combination With Retifanlimab and Radiation With/Without Temozolomide in Subjects With Glioblastoma

NCT05083754

RECRUITING Phase 2

Atezolizumab Plus Etoposide and Platinum in Small Cell Bladder Cancer

NCT05312671

RECRUITING NA

Cardiometabolic Screening Program

NCT05386719

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What the Pipeline for Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Shows

According to the ClinicalTrials.gov registry, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins is linked to 523 US clinical trials across every stage of research activity. Of those, 69 studies are currently recruiting, about 13% of the sponsor's indexed portfolio, and 301 are already marked complete, representing roughly 58% of the total.

The phase mix for Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins reports 5 late-stage studies (Phase 3 and Phase 4 combined) and 395 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins is Prostate Cancer with 17 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.