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ACTIVE NOT RECRUITING Phase 1

Study of PYX-106 in Solid Tumors

NCT05718557 · View on ClinicalTrials.gov ↗

Study Summary

The primary objective of this study is to determine the recommended dose(s) of PYX-106 in participants with relapsed/refractory solid tumors.

Conditions Studied

Interventions

  • DRUG PYX-106

Study Locations (20)

Madrid

  • START Madrid - Hospital Universitario Fundación Jiménez Díaz — Madrid
  • Hospital Universitario 12 de Octubre — Madrid
  • HM Centro Integral Oncológico Clara Campal — Madrid

California

  • University of California San Diego — La Jolla
  • University of Southern California — Los Angeles

Arizona

  • HonorHealth Research Institute — Scottsdale

Colorado

  • SCRI- HealthOne Denver — Denver

Georgia

  • Winship Cancer Institute of Emory University — Atlanta

Illinois

  • University of Chicago Medicine — Chicago

Massachusetts

  • Dana-Farber Cancer Institute — Boston

Ohio

  • Gabrail Cancer and Research Center — Canton

Trial Details

FieldValue
Enrollment Target 47 participants
Start Date 2023-05-23
Est. Completion 2026-05
Phase Phase 1

Sponsor

Pyxis Oncology

3 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05718557

The ClinicalTrials.gov registry entry for NCT05718557 describes a study currently listed as active not recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 47 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Pyxis Oncology, which has 3 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Solid Tumor appearing as the primary indexed condition, and to 1 intervention — of which PYX-106 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05718557 reports 20 study locations spanning 17 distinct geographic areas — top geographies include Madrid, California, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05718557 about?

NCT05718557 is a clinical study titled "Study of PYX-106 in Solid Tumors". The primary objective of this study is to determine the recommended dose(s) of PYX-106 in participants with relapsed/refractory solid tumors.

What is the current status of trial NCT05718557?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 47 participants. The study started on 2023-05-23. Estimated completion is 2026-05.

What conditions does trial NCT05718557 study?

This clinical trial studies the following conditions: Solid Tumor. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05718557?

The interventions under investigation include: PYX-106 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05718557?

This trial is sponsored by Pyxis Oncology, which has 3 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05718557 being conducted?

This trial has 20 study locations across Arizona, California, Colorado, Georgia, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial