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Type 1 Diabetes: early-phase trial registry
79 of 199 indexed Type 1 Diabetes trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #50 of 28,707 conditions by registered trial count.
199 US clinical trials · 79 currently recruiting · #50 of 28,707 conditions by registered trial count
Type 1 Diabetes: 199 US clinical trials tracked, 79 recruiting.
Type 1 Diabetes is the subject of 199 registered US clinical trials on ClinicalTrials.gov, 79 of them currently open to new participants. 21 are in Phase 3-4 (later-stage) and 54 in Phase 1-2 (earlier-stage). The most active sponsor is University of Colorado, Denver, running 16 of these trials.
Enrollment posture brief
Registry condition type-1-diabetes
OPEN 79 | RECR 40% | LATE 21 | EARLY 54 | RANK #50 | SPON 16
Volume-matched condition peers
Nearest open-share peer: Pregnancy (40% recruiting · 194 trials)
Type 1 Diabetes lists 79 open slots (40% of 199 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Type 1 Diabetes on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Type 1 Diabetes is recruiting above its size-band peers.
79 of 199 indexed trials (39.7%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Type 1 Diabetes trials is spread across many organizations.
University of Colorado, Denver accounts for 16 of 199 trials (8%). 97 distinct sponsors appear on at least one study for this condition label.
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Most Type 1 Diabetes trials plan to enrol fewer than 100 people.
Median target enrolment is 43 among the 199 trials that report a genuine target (sentinel values excluded). 141 of those (70.9%) plan for fewer than 100 participants.
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Type 1 Diabetes research is mostly interventional.
169 interventional and 30 observational studies make up this index (84.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
199 total, page 1 of 4
The T1D Exchange Registry
T1D Exchange, United States
NCT04629586
General Population Level Estimation for Type 1 Diabetes Risk in Children During Routine Care Delivery
Sanford Health
NCT04477928
PRenatal and Obstetric Maternal Exposures and ISlet Autoantibodies in Early Life
University of Colorado, Denver
NCT06141434
Genetics Of Autoimmunity In Type I Diabetes
Medical College of Wisconsin
NCT03648918
Immune Function and the Progression to T1D
University of Florida
NCT05899439
Post Market Registry for the Omnipod 5 System in Children and Adults With Type 1 Diabetes
Insulet Corporation
NCT06144554
The iLet Experience Study
Beta Bionics
NCT06891898
Commercial or Open Source Closed Loop Impact on Pregnancy Study
University of California, San Francisco
NCT06654713
A Longitudinal, Observational Study Comparing Real-World Experiences of Teplizumab-Treated and Untreated Participants With Stage 2 Type 1 Diabetes in the United States
Sanofi
NCT07260110
ACCESS 2: AI for pediatriC diabetiC Eye examS Study 2
Johns Hopkins University
NCT05463289
Health Behavior Intervention for Adults With Type 1 Diabetes
Emory University
NCT05823142
EMPoWER Study - Strengths-based Behavioral Intervention for Youth With Type 1 Diabetes
Baylor College of Medicine
NCT06014879
ACT1VATE: Addressing Emotional Distress to Improve Outcomes Among Diverse Adults With Type 1 Diabetes
Scripps Whittier Diabetes Institute
NCT04933851
Study Comparing Acceptance and Commitment Therapy to Supportive Diabetes Counseling and a Waitlist Control for Eating Disorders in Type 1 Diabetes
Duke University
NCT05540704
Family Intervention for Black Teens With Type 1 Diabetes
Wayne State University
NCT06275412
Accessing Care, Clinical Trials and Screening for Underserved Children and Adults With Type 1 Diabetes (ACCESS-T1D)
AdventHealth Translational Research Institute
NCT06908057
Registry for Stage 2 Type 1 Diabetes
Sanofi
NCT06481904
Remedy to Diabetes Distress (R2D2): A Scalable Screen to Treat Program for School-age Families
Nemours Children's Clinic
NCT05268250
Diabetes in African Youth
University of Minnesota
NCT05454176
SAFety and Efficacy of Human Anti-thymocyte ImmunoGlobUlin SAB-142 ARresting Progression of Type 1 Diabetes
SAb Biotherapeutics
NCT07187531
Impact of MEnstruation on Glycemic Response and Exercise In Females With Type 1 Diabetes
University of Colorado, Denver
NCT06297980
Sleep Coach for Adolescents With Type 1 Diabetes
Vanderbilt University Medical Center
NCT06516614
Discovery Diabetes
Vanderbilt University Medical Center
NCT07116434
Cholesterol Lowering and Residual Risk in Diabetes, Type 1
NYU Langone Health
NCT05641753
A Randomized Phase 1/2 Trial of Low Dose Anti-thymocyte Globulin (ATG) With Subsequent Adalimumab or Verapamil in New Onset Type 1 Diabetes
City of Hope Medical Center
NCT07061574
Accuracy of Continuous Glucose Monitors During the Perioperative Period in Youth With Type 1 Diabetes
University of Colorado, Denver
NCT06575842
The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action
Heba M. Ismail
NCT05414409
A Study Comparing Dexcom Continuous Glucose Monitoring to Point of Care Glucose Testing for the Management of Hospital and Post-Discharge Subjects With Type 1 Diabetes
Emory University
NCT06752928
Pathogenesis of Kidney Disease in Type 1 Diabetes: a Modern Kidney Biopsy Cohort (The PANDA Study)
University of Colorado, Denver
NCT05319990
T1CARE: A Trial of a Novel Intervention to Address Social Determinants of Health in Young Adults With Type 1 Diabetes
Yale University
NCT07059806
Repeat BCG Vaccinations for the Treatment of New Onset Type 1 Diabetes in Children Age 8-<18 Years
Massachusetts General Hospital
NCT05866536
InvesT1D: Promoting Adolescent Investment in Diabetes Care
Harvard Pilgrim Health Care
NCT06384911
Telemedicine-Delivered Unified Protocol for Cognitive Behavioral Therapy for Anxiety and Depression
Albert Einstein College of Medicine
NCT05734313
Reducing Diabetes Distress Using Cognitive Behavioral Therapy in Young Adults With Type 1 Diabetes
Albert Einstein College of Medicine
NCT05000021
CGM Academy for Youth With Type 1 Diabetes
Children's Hospital Los Angeles
NCT06408207
Skeletal Effects of Type 1 Diabetes on Low-Trauma Fracture Risk
Creighton University
NCT05701254
Transdisciplinary Care for Young Adults With Type 1 Diabetes
Nemours Children's Clinic
NCT06172166
CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)
COUR Pharmaceutical Development Company
NCT06783309
TArgeting Type 1 Diabetes Using POLyamines (TADPOL)
Emily K. Sims
NCT05594563
MANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sensitivity, and Cardiometabolic Function in Youth With Type 1 Diabetes
Kalie Tommerdahl
NCT05065372
Precision Administration of Anti-thymocyte Globulin With or Without Verapamil
University of Florida
NCT06455319
Trial of Semaglutide for Diabetic Kidney Disease in Type 1 Diabetes
University of Washington
NCT05822609
Home-based Oral Glucose Tolerance Test for Type 1 Diabetes Screening
Yale University
NCT07155252
The Effect of Glycemic Control and of GLP-1 Receptor Agonism on Islet GLP-1 in People With Type 1 and Type 2 Diabetes
Mayo Clinic
NCT06976619
GO TEAM: Glucose Optimization Through Technology Assisted Management
Sarah MacLeish
NCT06074458
Clinical Application of Stem Cell Educator Therapy in Type 1 Diabetes
Throne Biotechnologies
NCT04011020
Pancreas Ultrasound Imaging in type1 Diabetes
University of Colorado, Denver
NCT05482321
Denosumab for Type 1 Diabetes
City of Hope Medical Center
NCT06524960
AIDANET At Home Study
Sue Brown
NCT07039617
Expansion of the T1DES Pilot to a Public Hospital
Kaiser Permanente
NCT06494722
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 30 |
| Phase 2 | 24 |
| Phase 3 | 11 |
| Phase 4 | 10 |
Top Sponsors
Named interventions
Most-linked intervention names on Type 1 Diabetes records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Type 1 Diabetes trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Type 1 Diabetes page
199 registered trials, 79 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 79 Type 1 Diabetes trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of Colorado, Denver sponsors the most Type 1 Diabetes trials on record, review their full trial history before evaluating a specific study. See University of Colorado, Denver's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Type 1 Diabetes condition card totals 199 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.