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NCT05704985 · ClinicalTrials.gov registry record · Phase 1

Evaluating Safety and Biomarkers Using DK210 (EGFR) for Locally Advanced or Metastatic EGFR+ Tumors

A Phase 1 study of Cancer and Non-Small Cell Lung Cancer, sponsored by DEKA Biosciences.

Active
Registry status
Phase 1
Development phase
39
Enrollment target
7
Study locations

NCT05704985 is a Phase 1 study of Cancer and Non-Small Cell Lung Cancer that is active but no longer recruiting, run by DEKA Biosciences. The registered enrollment target is 39 participants, below the 3,491-participant average among 615 other Cancer trials with a reported enrollment target (99% lower). The trial reports 7 study locations across 5 states.

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The verdict

NCT05704985, a Phase 1 study of Cancer and Non-Small Cell Lung Cancer, is active but no longer recruiting, sponsored by DEKA Biosciences.

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
39 participants
Enrollment target
7
Study locations

Study Summary

This study will evaluate safety, pharmacodynamics and biomarkers of subcutaneous (SC) DK210(EGFR) given as monotherapy and in combination with immunotherapy, chemotherapy or radiation.

Interventions

  • DRUG Chemotherapy
  • RADIATION Radiation therapy
  • BIOLOGICAL DK210 (EGFR)
  • BIOLOGICAL Immune checkpoint blockers

Study Locations (7)

Texas

  • Mary Crowley Cancer Research - Dallas
  • University of Texas Southwestern - Dallas
  • The University of Texas M.D. Anderson Cancer Center - Houston

California

  • City of Hope - Duarte

New York

  • Northwell Health - Manhasset

Oklahoma

  • OU Health Stephenson Cancer Center - Oklahoma City

Virginia

  • NEXT Oncology - Fairfax

Trial Details

FieldValue
Enrollment Target 39 participants
Start Date 2023-04-03
Est. Completion 2025-10
Phase Phase 1

Sponsor

DEKA Biosciences

1 total trials

What the Registry Record Tells You About NCT05704985

The ClinicalTrials.gov registry entry for NCT05704985 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 39 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 3,491-participant average among 615 other Cancer trials with a reported enrollment target (99% lower). The listed sponsor is DEKA Biosciences, which has 1 total studies on file at ClinicalTrials.gov.

The record links to 9 conditions, with Cancer appearing as the primary indexed condition, and to 4 interventions - of which Chemotherapy is the first listed.

NCT05704985 reports 7 study locations spanning 5 distinct geographic areas - top geographies include Texas, California, New York.

Frequently Asked Questions

What is clinical trial NCT05704985 about?

NCT05704985 is a clinical study titled "Evaluating Safety and Biomarkers Using DK210 (EGFR) for Locally Advanced or Metastatic EGFR+ Tumors". This study will evaluate safety, pharmacodynamics and biomarkers of subcutaneous (SC) DK210(EGFR) given as monotherapy and in combination with immunotherapy, chemotherapy or radiation.

What is the current status of trial NCT05704985?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 39 participants. The study started on 2023-04-03. Estimated completion is 2025-10.

What conditions does trial NCT05704985 study?

This clinical trial studies the following conditions: Cancer, Non-Small Cell Lung Cancer, Colorectal Cancer, Head and Neck Cancer, Solid Tumor.

What interventions are being tested in trial NCT05704985?

The interventions under investigation include: Chemotherapy (DRUG), Radiation therapy (RADIATION), DK210 (EGFR) (BIOLOGICAL), Immune checkpoint blockers (BIOLOGICAL).

Who is sponsoring clinical trial NCT05704985?

This trial is sponsored by DEKA Biosciences, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05704985 being conducted?

This trial has 7 study locations across California, New York, Oklahoma, Texas, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.