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NCT05076552 · ClinicalTrials.gov registry record · Phase 1
A Study to Assess the Safety, Pharmacokinetics, and Antitumor Activity of Oral TACH101 in Participants With Advanced or Metastatic Cancer
A Phase 1 study of Solid Tumor and Advanced Cancer, sponsored by Tachyon Therapeutics.
- Active
- Registry status
- Phase 1
- Development phase
- 30
- Enrollment target
- 8
- Study locations
NCT05076552 is a Phase 1 study of Solid Tumor and Advanced Cancer that is active but no longer recruiting, run by Tachyon Therapeutics. The registered enrollment target is 30 participants, below the 221-participant average among 196 other Solid Tumor trials with a reported enrollment target (86% lower). The trial reports 8 study locations across 6 states.
The verdict
NCT05076552, a Phase 1 study of Solid Tumor and Advanced Cancer, is active but no longer recruiting, sponsored by Tachyon Therapeutics.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 30 participants
- Enrollment target
- 8
- Study locations
Study Summary
The main objective for part 1a of the study is to determine the maximum tolerated dose (MTD) and recommended Phase 2 dose (RP2D) and to evaluate the safety, tolerability, pharmacokinetics, and antitumor activity of oral TACH101 in participants with advanced and metastatic solid tumors. For part 1b, the main objective is the objective response rate (ORR) as assessed by radiographic progression measured by Response Evaluation Criteria in Solid Tumors (RECIST) v1.1.
Conditions Studied
Interventions
- DRUG TACH101
Study Locations (8)
Texas
- NEXT Oncology - Austin
- MD Anderson - Houston
- NEXT Oncology - San Antonio
California
- UCI Health - Orange
Colorado
- Sarah Cannon Research Institute - Denver
Florida
- Sarah Cannon Research Institute - Orlando
Tennessee
- Sarah Cannon Research Institute - Nashville
Virginia
- NEXT Oncology - Fairfax
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2023-02-17 |
| Est. Completion | 2025-07 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05076552
The ClinicalTrials.gov registry entry for NCT05076552 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 221-participant average among 196 other Solid Tumor trials with a reported enrollment target (86% lower). The listed sponsor is Tachyon Therapeutics, which has 1 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Solid Tumor appearing as the primary indexed condition, and to 1 intervention - of which TACH101 is the first listed.
NCT05076552 reports 8 study locations spanning 6 distinct geographic areas - top geographies include Texas, California, Colorado.
Frequently Asked Questions
What is clinical trial NCT05076552 about?
NCT05076552 is a clinical study titled "A Study to Assess the Safety, Pharmacokinetics, and Antitumor Activity of Oral TACH101 in Participants With Advanced or Metastatic Cancer". The main objective for part 1a of the study is to determine the maximum tolerated dose (MTD) and recommended Phase 2 dose (RP2D) and to evaluate the safety, tolerability, pharmacokinetics, and antitumor activity of oral TACH101 in participants with advanced and metastatic solid tumors. For part 1b, ...
What is the current status of trial NCT05076552?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2023-02-17. Estimated completion is 2025-07.
What conditions does trial NCT05076552 study?
This clinical trial studies the following conditions: Solid Tumor, Advanced Cancer, Metastatic Solid Tumor.
What interventions are being tested in trial NCT05076552?
The interventions under investigation include: TACH101 (DRUG).
Who is sponsoring clinical trial NCT05076552?
This trial is sponsored by Tachyon Therapeutics, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05076552 being conducted?
This trial has 8 study locations across California, Colorado, Florida, Tennessee, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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