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Overactive Bladder
Open-data reference.
47 US clinical trials · 21 currently recruiting
Active & Recent Trials
Noninvasive Ultrasound Assessment of Detrusor Dysfunction
Mayo Clinic
NCT05652023
Pelvic Health Electrically Evoked Recording (PEER) 2 Study
MedtronicNeuro
NCT05200923
TReating Incontinence for Underlying Mental and Physical Health
University of California, San Francis
NCT05362292
Detrusor Nerve Radiofrequency Ablation for Overactive Bladder in Women
InMode MD
NCT07209397
A Real World Study of eCoin for Urgency Urinary Incontinence: Post Approval Evaluation (RECIPE)
Valencia Technologies Corporation
NCT05685433
Antibiotic Usage Prior to OnabotulinumtoxinA Injection
Benaroya Research Institute
NCT04754737
Percutaneous Nerve Evaluation Trial Time
University of Chicago
NCT06226220
Standard Injections Versus Reduced Injections for Intravesical onabotulinumtoxinA Treatment of Overactive Bladder
Walter Reed National Military Medical Center
NCT04020510
BTL Emsella Chair Versus Sham for the Treatment of Overactive Bladder
Corewell Health East
NCT04873037
Sacral Neuromodulation for Male Overactive Bladder (MOAB)
Axonics
NCT06511141
Bladder Botox UTI Antibiotic Prophylaxis
Walter Reed National Military Medical Center
NCT06387329
Examining the Effects of Intra-detrusor Botox at Time of HoLEP in Men With Overactive Bladder Symptoms
Northwestern University
NCT05878951
Fluoroscopy Radiation Reduction During Sacral Neuromodulation Lead Placement
Loma Linda University
NCT04527445
Yoga for Treatment of Overactive Bladder in Pediatric Patients
Duke University
NCT05895045
Urinary Microbiome Changes Following Administration of 500 mg of NDS-446 in Women With Dry OAB at 12 Weeks
Loyola University
NCT05557279
At-Home Transcutaneous Tibial Nerve Stimulation for Overactive Bladder in Rural Women
Oregon Health and Science University
NCT07178314
Home Versus Office Removal of Percutaneous Nerve Evaluation (PNE) Lead
The Cleveland Clinic
NCT05799313
Neuromodulating Cortical Regions Involved in Neurogenic Bladder in MS
The Methodist Hospital Research Institute
NCT06072703
Add-On ZIDA Sock Therapy for Overactive Bladder
Medical University of South Carolina
NCT07432659
Predictive Utility and Mechanisms of Sacral Evoked Responses in Sacral Neuromodulation
University of Michigan
NCT06983470
rTMS in Overactive Bladder
The Methodist Hospital Research Institute
NCT06198439
Reduced-dose Botox for Urgency Incontinence Among Elder Females
Dartmouth-Hitchcock Medical Center
NCT05512039
A Study to Evaluate Once Daily Low Dose and High Dose Solabegron or Placebo Given for 12 Weeks to Treat Women With Symptoms of Overactive Bladder: Sudden Urge to Urinate, Frequent Urination Associated With Wetting Episodes (VEL-2001)
Velicept Therapeutics
NCT03594058
Study of Botulinum Toxin Type A for the Treatment of Patients With Idiopathic Overactive Bladder With Urinary Incontinence
Allergan
NCT00910845
Study of 2 Doses of Solifenacin Succinate in Female Subjects With Overactive Bladder.
Astellas Pharma
NCT01093534
Efficacy, Safety, and Tolerability of Darifenacin in Patients Aged > 65 Years With Overactive Bladder
Novartis
NCT00171184
OnabotulinumtoxinA (BOTOX®) Treatment for Urinary Incontinence in Patients With Overactive Bladder
Allergan
NCT01945489
Anticholinergic vs. Botox Comparison Study
NICHD Pelvic Floor Disorders Network
NCT01166438
Combined Behavioral and Drug Treatment of Overactive Bladder in Men
University of Alabama at Birmingham
NCT01175382
PRospective Study to Evaluate EffectivenesS With the NURO™ PErcutaneous Tibial Neuromodulation System in Patients With OAB
MedtronicNeuro
NCT02857816
Bacterial Genomic Sequencing in Overactive Bladder
Loyola University
NCT01642277
Trospium Chloride XR in Obese Female Patients With Overactive Bladder
Allergan
NCT00932022
Intradetrusor Botulinum Toxin A for OAB Via 1 Versus 10 Injections: A Randomized Clinical Trial
University of California, Irvine
NCT05308979
Overactive Bladder Innovative Therapy Trial (OrBIT)
Uroplasty
NCT00448175
Prophylactic Antibiotic Administration for Bladder OnabotulinumtoxinA Injection
The Cleveland Clinic
NCT05719285
Combined Anticholinergic Medication and Sacral Neuromodulation to Treat Refractory Overactive Bladder
University of California, Irvine
NCT01047046
Behavioral or Solifenacin Therapy for Urinary Symptoms in Parkinson Disease
VA Office of Research and Development
NCT03149809
Evaluation of the Effect of Dried Cranberry Powder in Women With Dry OAB
Weill Medical College of Cornell University
NCT03017170
Clinical Trial to Study a Non-invasive Neurostimulation Device on Urgency (Urinary) Incontinence Overactive Bladder (OAB)
Ethicon Endo-Surgery
NCT01125722
A Pilot Study Evaluating the Usability of the Oabi Mobile Application
Massachusetts General Hospital
NCT04534946
Botulin-A Toxin Instillations and Overactive Bladder
Mayo Clinic
NCT00583219
A Study To Test The Interaction of Two Medications for Treatment of Overactive Bladder
GlaxoSmithKline
NCT00501267
Pilot Study: Is Overactive Bladder Caused by Subacute Urinary Tract Infections?
University of Rochester
NCT00714792
A Two-Part Study to Determine: Best Medication Formulation and Food Effect
GlaxoSmithKline
NCT00427596
Higher Neural Changes Following Anticholinergic, Beta 3 Agonist, or Placebo in Patients With Overactive Bladder
Baylor Research Institute
NCT03817931
Clinical Feasibility Study, Implantable Tibial Nerve Stimulator (ITNS)
Nine Continents Medical
NCT04115228
Two Phase Extension Trial of SP668 to Investigate the Safety and Tolerability of Sustained Release Fesoterodine in Subjects With Overactive Bladder: a Double-Blind Phase Followed by an Open-Label Extension Phase
Pfizer
NCT00220389
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 5 |
| Phase 2 | 5 |
| Phase 3 | 3 |
| Phase 4 | 12 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Overactive Bladder Trial Landscape
ClinicalTrials.gov lists 47 US studies indexed under Overactive Bladder, and 21 of those are currently open to recruitment — roughly 45% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Overactive Bladder shows 15 late-stage studies (Phase 3 and Phase 4 combined) alongside 10 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Overactive Bladder is led by Allergan with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 47 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Overactive Bladder?
PlainTrial tracks 47 US clinical trials for Overactive Bladder, of which 21 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Overactive Bladder?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.