The Methodist Hospital Research Institute

126 total trials 49 currently recruiting 48 completed

The Methodist Hospital Research Institute sponsors 126 registered US clinical trials on ClinicalTrials.gov, 49 of them currently recruiting, and 48 completed. 12 of these trials are in Phase 3-4 (later-stage) and 65 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Urge Incontinence, with 2 trials.

Trial Pipeline

126 total, page 1 of 3

RECRUITING Phase 1

Stem Cells for Erectile Dysfunction Post RALP

NCT07048314

RECRUITING Phase 1

Interleukine-2 (IL-2) Plus Semaglutide in Alzheimer's Disease

NCT07651319

RECRUITING Phase 1

Dexamethasone for Ureteral STent Symptoms (DUSTS)

NCT06930690

RECRUITING NA

VR-Based Cognitive Stimulation Games for Delirium Prevention

NCT07641153

RECRUITING Phase 1

Anterior Cruciate Ligament (ACL) Reconstruction With Autologous Fat Pad Derived Mesenchymal Stem Cells

NCT06798623

RECRUITING Phase 2

Trial to Study Anti- HCMV Therapy in Breast Cancer Patients With Progressive Intracranial Metastases and CMV Infection

NCT07383649

RECRUITING Phase 2

Trial of 5-Fluorouracil (5FU)-Based Therapy in Combination With Fruquintinib in Patients With Locally Advanced Unresectable or Metastatic Colorectal Cancer

NCT07042685

RECRUITING NA

Bone Stimulator for Spondylolysis

NCT06666608

RECRUITING NA

VoiceLove Digital Therapy for Delirium in the ICU

NCT07218484

RECRUITING Phase 2

Comprehensive Multimodal Prehabilitation Alone or With Neoadjuvant Therapy Before Major Cancer Surgery

NCT07050771

RECRUITING Phase 1

Neoadjuvant High Dose Rate Brachytherapy Prior to Radical Prostatectomy in Patients With Prostate Cancer

NCT07182279

RECRUITING Phase 1

Intraosseous (IO) Cefazolin and Vancomycin in Primary Total Knee Arthroplasty (TKA)

NCT06640491

RECRUITING Phase 2

5-Fluorouracil/Leucovorin (5FU/LV) in Combination With Regorafenib in Patients With Metastatic Colorectal Cancer

NCT06887218

RECRUITING NA

Non-invasive VNS in Stroke Recovery

NCT06761404

RECRUITING NA

Prehabilitation for Kidney Transplant Candidates

NCT06886256

RECRUITING NA

Blood Flow Restriction (BFR) Training on the Ulnar Collateral Ligament (UCL)

NCT06664827

RECRUITING NA

Personalized Transcranial Direct Current Stimulation in Stroke Recovery

NCT06286800

RECRUITING NA

Home Tele Rehabilitation Therapy for Vascular Dementia

NCT06289569

RECRUITING Phase 1

Phase I Trial of 5-Fluorouracil (5FU) -Based Therapy in Combination With Hydroxytyrosol (HT) in Patients With Advanced or Metastatic Colorectal Cancer

NCT06833866

RECRUITING Phase 4

Intraosseous vs. Intravenous Vancomycin Administration in Total Ankle Arthroplasty

NCT06384651

RECRUITING Phase 1

Thymalfasin (Thymosin Alpha 1; Ta1) as an Enhancer of Vaccine Response Among Older Adults Receiving Booster Doses of COVID-19 Vaccine

NCT06821100

RECRUITING Phase 1

Honokiol in Early-Stage Resectable Non-Small Cell Lung Cancer

NCT06566443

RECRUITING Phase 4

Intraosseous Morphine Administration During Anterior Cruciate Ligament Reconstruction

NCT06511232

RECRUITING NA

Augmenting Rehabilitation Outcomes and Functional Neuroplasticity Using Epidural Stimulation of Cervical Spinal Cord

NCT06225245

RECRUITING Phase 1

ATRA and Carfilzomib in Plasma Cell Myeloma Patients

NCT06536413

RECRUITING

MRI Guided Management of Occlusive Peripheral Arterial Disease

NCT06782100

RECRUITING Phase 3

Spiritual Care or Psychotherapy Versus Palliative Care Alone in Patients With Non-Curative Malignancies

NCT07290491

RECRUITING Phase 1

CBD for Pain Following Orthopedic Shoulder Surgery

NCT06381791

RECRUITING Phase 1

IL-2 Plus Abatacept in FTD

NCT06395038

RECRUITING NA

Endoscopic Sleeve Gastroplasty (ESG) for the Treatment of Obesity

NCT06339320

RECRUITING NA

Protein Supplementation After ACL Surgery

NCT06311058

RECRUITING NA

rTMS in Overactive Bladder

NCT06198439

RECRUITING NA

Harnessing Neuroplasticity of Postural Sensorimotor Networks Using Non-Invasive Spinal Neuromodulation to Maximize Functional Recovery After Spinal Cord Injury

NCT06213012

RECRUITING NA

Neuromodulating Cortical Regions Involved in Neurogenic Bladder in MS

NCT06072703

RECRUITING Phase 2

Venous Ethanol for Ventricular Tachycardia

NCT05511246

RECRUITING Phase 2

Systemic and Central Inflammation in AD

NCT06384378

RECRUITING Phase 4

Atezolizumab and Bevacizumab Pre-Liver Transplantation for Patients With Hepatocellular Carcinoma Beyond Milan Criteria

NCT05185505

RECRUITING

Selective PET Imaging of Astrocytes and Microglia in Alzheimer's Disease

NCT05582200

RECRUITING Phase 2

Alpelisib/iNOS Inhibitor/Nab-paclitaxel in Patients With HER2 Negative Metaplastic Breast Cancer (MpBC)

NCT05660083

RECRUITING Phase 2

Phase II Clinical Trial of Interleukin-2 in AD

NCT06096090

RECRUITING NA

LSTR in Chevron Osteotomy

NCT06486753

RECRUITING Phase 2

Fulvestrant+Abemaciclib With Run-In of Fulvestrant in Er-Positive, Her2-Negative Metastatic Breast Cancer

NCT05305924

RECRUITING

Dynamics of Colonization and Infection by Multidrug-Resistant Pathogens in Immunocompromised and Critically Ill Patients

NCT06258551

RECRUITING Phase 2

Clazakizumab vs. Placebo - COVID-19 Infection

NCT04494724

RECRUITING Phase 1

Ocrelizumab for Psychosis by Autoimmunity

NCT03971487

RECRUITING NA

Effect of BFR Rehab After Achilles Tendon Rupture

NCT06254794

RECRUITING NA

Limb Occlusion Pressure Tourniquets to Decrease Pain After Surgery

NCT04390425

RECRUITING Phase 1

HSV-tk and XRT and Chemotherapy for Newly Diagnosed GBM

NCT03603405

RECRUITING Phase 1

HSV-tk + Valacyclovir Therapy in Combination With Brachytherapy for Recurrent Prostate Cancer

NCT01913106

ACTIVE NOT RECRUITING Phase 4

IO Vancomycin in TSA

NCT05831774

Page 1 of 3 Next →

What the Pipeline for The Methodist Hospital Research Institute Shows

According to the ClinicalTrials.gov registry, The Methodist Hospital Research Institute is linked to 126 US clinical trials across every stage of research activity. Of those, 49 studies are currently recruiting, about 39% of the sponsor's indexed portfolio, and 48 are already marked complete, representing roughly 38% of the total.

The phase mix for The Methodist Hospital Research Institute reports 12 late-stage studies (Phase 3 and Phase 4 combined) and 65 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for The Methodist Hospital Research Institute is Urge Incontinence with 2 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.