The Methodist Hospital Research Institute
The Methodist Hospital Research Institute sponsors 126 registered US clinical trials on ClinicalTrials.gov, 49 of them currently recruiting, and 48 completed. 12 of these trials are in Phase 3-4 (later-stage) and 65 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Urge Incontinence, with 2 trials.
Trial Pipeline
126 total, page 1 of 3
Stem Cells for Erectile Dysfunction Post RALP
NCT07048314
Interleukine-2 (IL-2) Plus Semaglutide in Alzheimer's Disease
NCT07651319
Dexamethasone for Ureteral STent Symptoms (DUSTS)
NCT06930690
VR-Based Cognitive Stimulation Games for Delirium Prevention
NCT07641153
Anterior Cruciate Ligament (ACL) Reconstruction With Autologous Fat Pad Derived Mesenchymal Stem Cells
NCT06798623
Trial to Study Anti- HCMV Therapy in Breast Cancer Patients With Progressive Intracranial Metastases and CMV Infection
NCT07383649
Trial of 5-Fluorouracil (5FU)-Based Therapy in Combination With Fruquintinib in Patients With Locally Advanced Unresectable or Metastatic Colorectal Cancer
NCT07042685
Bone Stimulator for Spondylolysis
NCT06666608
VoiceLove Digital Therapy for Delirium in the ICU
NCT07218484
Comprehensive Multimodal Prehabilitation Alone or With Neoadjuvant Therapy Before Major Cancer Surgery
NCT07050771
Neoadjuvant High Dose Rate Brachytherapy Prior to Radical Prostatectomy in Patients With Prostate Cancer
NCT07182279
Intraosseous (IO) Cefazolin and Vancomycin in Primary Total Knee Arthroplasty (TKA)
NCT06640491
5-Fluorouracil/Leucovorin (5FU/LV) in Combination With Regorafenib in Patients With Metastatic Colorectal Cancer
NCT06887218
Non-invasive VNS in Stroke Recovery
NCT06761404
Prehabilitation for Kidney Transplant Candidates
NCT06886256
Blood Flow Restriction (BFR) Training on the Ulnar Collateral Ligament (UCL)
NCT06664827
Personalized Transcranial Direct Current Stimulation in Stroke Recovery
NCT06286800
Home Tele Rehabilitation Therapy for Vascular Dementia
NCT06289569
Phase I Trial of 5-Fluorouracil (5FU) -Based Therapy in Combination With Hydroxytyrosol (HT) in Patients With Advanced or Metastatic Colorectal Cancer
NCT06833866
Intraosseous vs. Intravenous Vancomycin Administration in Total Ankle Arthroplasty
NCT06384651
Thymalfasin (Thymosin Alpha 1; Ta1) as an Enhancer of Vaccine Response Among Older Adults Receiving Booster Doses of COVID-19 Vaccine
NCT06821100
Honokiol in Early-Stage Resectable Non-Small Cell Lung Cancer
NCT06566443
Intraosseous Morphine Administration During Anterior Cruciate Ligament Reconstruction
NCT06511232
Augmenting Rehabilitation Outcomes and Functional Neuroplasticity Using Epidural Stimulation of Cervical Spinal Cord
NCT06225245
ATRA and Carfilzomib in Plasma Cell Myeloma Patients
NCT06536413
MRI Guided Management of Occlusive Peripheral Arterial Disease
NCT06782100
Spiritual Care or Psychotherapy Versus Palliative Care Alone in Patients With Non-Curative Malignancies
NCT07290491
CBD for Pain Following Orthopedic Shoulder Surgery
NCT06381791
IL-2 Plus Abatacept in FTD
NCT06395038
Endoscopic Sleeve Gastroplasty (ESG) for the Treatment of Obesity
NCT06339320
Protein Supplementation After ACL Surgery
NCT06311058
rTMS in Overactive Bladder
NCT06198439
Harnessing Neuroplasticity of Postural Sensorimotor Networks Using Non-Invasive Spinal Neuromodulation to Maximize Functional Recovery After Spinal Cord Injury
NCT06213012
Neuromodulating Cortical Regions Involved in Neurogenic Bladder in MS
NCT06072703
Venous Ethanol for Ventricular Tachycardia
NCT05511246
Systemic and Central Inflammation in AD
NCT06384378
Atezolizumab and Bevacizumab Pre-Liver Transplantation for Patients With Hepatocellular Carcinoma Beyond Milan Criteria
NCT05185505
Selective PET Imaging of Astrocytes and Microglia in Alzheimer's Disease
NCT05582200
Alpelisib/iNOS Inhibitor/Nab-paclitaxel in Patients With HER2 Negative Metaplastic Breast Cancer (MpBC)
NCT05660083
Phase II Clinical Trial of Interleukin-2 in AD
NCT06096090
LSTR in Chevron Osteotomy
NCT06486753
Fulvestrant+Abemaciclib With Run-In of Fulvestrant in Er-Positive, Her2-Negative Metastatic Breast Cancer
NCT05305924
Dynamics of Colonization and Infection by Multidrug-Resistant Pathogens in Immunocompromised and Critically Ill Patients
NCT06258551
Clazakizumab vs. Placebo - COVID-19 Infection
NCT04494724
Ocrelizumab for Psychosis by Autoimmunity
NCT03971487
Effect of BFR Rehab After Achilles Tendon Rupture
NCT06254794
Limb Occlusion Pressure Tourniquets to Decrease Pain After Surgery
NCT04390425
HSV-tk and XRT and Chemotherapy for Newly Diagnosed GBM
NCT03603405
HSV-tk + Valacyclovir Therapy in Combination With Brachytherapy for Recurrent Prostate Cancer
NCT01913106
IO Vancomycin in TSA
NCT05831774
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 30 |
| Phase 2 | 35 |
| Phase 3 | 2 |
| Phase 4 | 10 |
What the Pipeline for The Methodist Hospital Research Institute Shows
According to the ClinicalTrials.gov registry, The Methodist Hospital Research Institute is linked to 126 US clinical trials across every stage of research activity. Of those, 49 studies are currently recruiting, about 39% of the sponsor's indexed portfolio, and 48 are already marked complete, representing roughly 38% of the total.
The phase mix for The Methodist Hospital Research Institute reports 12 late-stage studies (Phase 3 and Phase 4 combined) and 65 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for The Methodist Hospital Research Institute is Urge Incontinence with 2 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.