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NCT05719285 · ClinicalTrials.gov registry record · Phase 4

Prophylactic Antibiotic Administration for Bladder OnabotulinumtoxinA Injection

A Phase 4 study of Overactive Bladder and Overactive Bladder Syndrome, sponsored by The Cleveland Clinic.

Completed
Registry status
Phase 4
Development phase
100
Enrollment target
1
Study location

NCT05719285 is a Phase 4 study of Overactive Bladder and Overactive Bladder Syndrome that has completed, run by The Cleveland Clinic. The registered enrollment target is 100 participants, below the 209-participant average among 45 other Overactive Bladder trials with a reported enrollment target (52% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05719285, a Phase 4 study of Overactive Bladder and Overactive Bladder Syndrome, has completed, sponsored by The Cleveland Clinic.

COMPLETED
Registry status
Phase 4
Development phase
100 participants
Enrollment target
1
Study location

Study Summary

The goal of this clinical trial is to evaluate the outcomes of differing durations of antibiotic prophylaxis with bladder onabotulinumtoxinA injection in patients with refractory overactive bladder. The main question it aims to answer are: • Is the incidence of post-procedure UTI similar between single-dose and multi-day durations of peri-procedural antibiotics? Participants will be randomized to single-dose versus multi-day dose of antibiotic prophylaxis with bladder onabotulinumtoxinA injection. Researchers will compare incidence of UTI in each group to see if there is a significant difference.

Interventions

  • DRUG Single-Dose Antibiotic
  • DRUG Multi-Dose Antibiotic

Study Locations (1)

Ohio

  • Cleveland Clinic Foundation - Cleveland

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 2022-12-06
Est. Completion 2023-06-08
Phase Phase 4

Sponsor

The Cleveland Clinic

688 total trials

What the Registry Record Tells You About NCT05719285

The ClinicalTrials.gov registry entry for NCT05719285 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 209-participant average among 45 other Overactive Bladder trials with a reported enrollment target (52% lower). The listed sponsor is The Cleveland Clinic, which has 688 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Overactive Bladder appearing as the primary indexed condition, and to 2 interventions - of which Single-Dose Antibiotic is the first listed.

NCT05719285 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.

Frequently Asked Questions

What is clinical trial NCT05719285 about?

NCT05719285 is a clinical study titled "Prophylactic Antibiotic Administration for Bladder OnabotulinumtoxinA Injection". The goal of this clinical trial is to evaluate the outcomes of differing durations of antibiotic prophylaxis with bladder onabotulinumtoxinA injection in patients with refractory overactive bladder. The main question it aims to answer are: • Is the incidence of post-procedure UTI similar between s...

What is the current status of trial NCT05719285?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 100 participants. The study started on 2022-12-06. Estimated completion is 2023-06-08.

What conditions does trial NCT05719285 study?

This clinical trial studies the following conditions: Overactive Bladder, Overactive Bladder Syndrome, Urinary Incontinence, Urge, Urge Incontinence.

What interventions are being tested in trial NCT05719285?

The interventions under investigation include: Single-Dose Antibiotic (DRUG), Multi-Dose Antibiotic (DRUG).

Who is sponsoring clinical trial NCT05719285?

This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05719285 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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