Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
Detrusor Nerve Radiofrequency Ablation for Overactive Bladder in Women
NCT07209397 · View on ClinicalTrials.gov ↗
Study Summary
The goal of this clinical trial is to learn if a vaginal radiofrequency (RF) device called MORPHEUSV works to treat overactive bladder (OAB) in women. Researchers also want to learn how safe the device is for this indication. This study will include women ages 22 to 80 who have had OAB symptoms for at least 6 months. The main questions it aims to answer are: Does the MORPHEUSV device lower the number of daily episodes of accidental urine leakage caused by urgency? Does it work better than a sham (placebo) treatment? Researchers will compare the MORPHEUSV device to a sham treatment to see how well it reduces symptoms of overactive bladder. Participants will: 1) Receive one session of either the MORPHEUSV or sham treatment. 2) Track their symptoms using a diary and questionnaires 3) Return for three to six follow-up visits over 12 months. This study is being conducted at multiple clinics in the United States.
Conditions Studied
Interventions
- DEVICE Detrusor nerve radiofrequency ablation
- DEVICE Simulated (sham) detrusor nerve radiofrequency ablation
Study Locations (9)
California
- Stanford Medicine Department of Obstetrics & Gynecology — Palo Alto
District of Columbia
- MedStar Health Research Institute — Washington D.C.
Idaho
- Advanced Specialty Research — Boise
Illinois
- University of Chicago Medicine Urogynecology — Chicago
Kansas
- Cypress Medical Research Center — Wichita
Massachusetts
- Bay State Clinical Trials — Watertown
Nebraska
- Urology Center, P.C. — Omaha
Nevada
- UNLV Kirk Kerkorian School of Medicine Department of Gynecologic Surgery & Obstetrics — Las Vegas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 202 participants |
| Start Date | 2025-11-25 |
| Est. Completion | 2027-11-30 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07209397
The ClinicalTrials.gov registry entry for NCT07209397 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 202 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is InMode MD, which has 32 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 7 conditions, with Overactive Bladder appearing as the primary indexed condition, and to 2 interventions — of which Detrusor nerve radiofrequency ablation is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT07209397 reports 9 study locations spanning 9 distinct geographic areas — top geographies include California, District of Columbia, Idaho. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT07209397 about?
NCT07209397 is a clinical study titled "Detrusor Nerve Radiofrequency Ablation for Overactive Bladder in Women". The goal of this clinical trial is to learn if a vaginal radiofrequency (RF) device called MORPHEUSV works to treat overactive bladder (OAB) in women. Researchers also want to learn how safe the device is for this indication. This study will include women ages 22 to 80 who have had OAB symptoms for ...
What is the current status of trial NCT07209397?
This trial is currently recruiting. It is a NA study. The enrollment target is 202 participants. The study started on 2025-11-25. Estimated completion is 2027-11-30.
What conditions does trial NCT07209397 study?
This clinical trial studies the following conditions: Overactive Bladder, Overactive Bladder (OAB), Urge Urinary Incontinence, Mixed Urinary Incontinence, Mixed Urinary Incontinence (Urge-Predominant). These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT07209397?
The interventions under investigation include: Detrusor nerve radiofrequency ablation (DEVICE), Simulated (sham) detrusor nerve radiofrequency ablation (DEVICE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT07209397?
This trial is sponsored by InMode MD, which has 32 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT07209397 being conducted?
This trial has 9 study locations across California, District of Columbia, Idaho, Illinois, Kansas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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