University of California, Irvine

353 total trials 266 currently recruiting 57 completed

Trial Pipeline

RECRUITING NA

Resilience in Reentry: Cognitive-Behavioral Resilience Training for Parolees With Adjustment Challenges

NCT07167719

RECRUITING Phase 2

Riluzole For Preventing Cognitive Dysfunction in Ca Pts Receiving Chemo (REFOCUS): Pilot Trial

NCT07447050

RECRUITING NA

HOPE Intervention for Fitness

NCT07114822

RECRUITING NA

Telemedicine to Support Living Kidney Donor Candidates

NCT07206069

RECRUITING Phase 1

Treating Anemia in Myelofibrosis With Repurposed Drugs (Nelfinavir) That Restore Iron Delivery to the Bone Marrow

NCT07281781

RECRUITING

Mapping Ibogaine Neural Dynamics in Opioid Use Disorder

NCT07226570

RECRUITING NA

Mobile Health Intervention to Improve Adherence to Oral Anticancer Therapy

NCT07073807

RECRUITING NA

Wearable Device and Behavioral Support for Enhancing Arm Use After Stroke

NCT07042152

RECRUITING NA

EndoPAT Device for Endothelial Dysfunction in ED

NCT06720597

RECRUITING Phase 1

Response Adapted Neoadjuvant Therapy in Gastroesophageal Cancers (RANT-GC Trial)

NCT05733689

RECRUITING NA

Lung Cancer Screening of Family Members of Patients With Mutation-Driven Lung Cancer

NCT07062172

RECRUITING Phase 1

Impact of Sodium Bicarbonate on 24-hour Urine Parameters in Hypocitriuric and Uric Acid Stone Formers

NCT06335537

RECRUITING Phase 1

Trial of Single Protein Encapsulated Doxorubicin, SPEDOX-6 in Advanced Malignancies

NCT07064018

RECRUITING NA

The THRIVE Study: Teaching Healthy Regulation in Individuals & Vulnerable Environments

NCT06821035

RECRUITING NA

MULTIsite Feasibility of MUSIc Therapy to Address Quality Of Life in Sickle Cell Disease

NCT06853158

RECRUITING NA

Conscious Pregnancy: Supporting Maternal Cardiometabolic Health With Mindfulness

NCT06898658

RECRUITING NA

Mechanistic and Clinical Outcomes of a Surgical Innovation Aimed at Minimizing GERD Associated With VSG (INNOVATE-VSG)

NCT06783751

RECRUITING NA

Analgesic Response to Opioids in Patients With Fibromyalgia After Conventional Acupuncture Versus Sham Acupuncture

NCT06571110

RECRUITING NA

My Life and My Experiences Project

NCT06821178

RECRUITING Phase 2

Metronomic Cyclophosphamide With Pembrolizumab in Checkpoint Inhibitor Refractory Melanoma

NCT06771544

RECRUITING Phase 2

Single-Center Eval of Clinical & Radiological Benefit AHCC in Combo W/ SOC Tx for HPV+ Pts W/ HNSCC

NCT06693323

RECRUITING NA

The Effects of Energy Healing in Fibromyalgia

NCT06552728

RECRUITING Phase 2

Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial

NCT06580002

RECRUITING Phase 2

Adjuvant Sacituzumab Govitecan and Nivolumab in Muscle-Invasive Urothelial Carcinoma At High-Risk Recurrence

NCT06682728

RECRUITING Early Phase 1

PhI Pilot Study Pafolacianine Inject for Intraoperative Imaging on Outcomes of GI Cancer Peritoneal Carcinomatosis

NCT06511037

RECRUITING NA

The Effects of Core Shamanism in Fibromyalgia

NCT06579261

RECRUITING Early Phase 1

Impact of Intraoperative ICG on Functional Outc in RARP

NCT06446648

RECRUITING Phase 2

CMV-TCIP Directed Letermovir Prophylaxis After Allo-SCT

NCT06453460

RECRUITING NA

A Biobehavioral Intervention for Latino/Hispanic Young Adults with Cancer

NCT06338475

RECRUITING Phase 4

Neuromuscular Blockade Comparison for GI-2 Recovery After Bowel Resection

NCT06112353

RECRUITING NA

mpMRI Compared to Diagnostic TURBT in Patients With Suspected Muscle-Invasive Bladder Cancer

NCT06335667

RECRUITING NA

Effect of Fasting on Patient Outcomes After Wide-Awake, Local Anesthesia-only, No Tourniquet (WALANT) Procedures

NCT05819801

RECRUITING NA

Positive Affect Treatment for Adolescents with Early Life Adversity

NCT06273137

RECRUITING

Assess Diversity of Gut Microbiome in Met NSCLC in Correlation to Tx & Adverse Effects

NCT06221800

RECRUITING

Impact of Personality on Adherence to Tyrosine Kinase Inhibitor Therapy in Pts w/Chronic Myeloid Leukemia

NCT06229860

RECRUITING

Shorter Versus Extended Course of Antibiotic Therapy for Necrotizing Soft Tissue Infections

NCT06002607

RECRUITING NA

A Biobehavioral Intervention to Reduce Adverse Outcomes in Young Adult Testicular Cancer Survivors

NCT05836688

RECRUITING Phase 2

Risk-ADAPTed Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation

NCT06028828

RECRUITING Phase 4

Pharmacotherapy in Conjunction With Lifestyle Counseling for Management of Weight Regain After Bariatric Surgery

NCT05975580

RECRUITING NA

Latinx Children and Surgery

NCT06020677

RECRUITING NA

Patient Derived Vascularized MicroTumor Model of Gastrointestinal Peritoneal Carcinomatosis

NCT05844865

RECRUITING NA

Vaginal Changes After CO2 Laser

NCT06691178

RECRUITING Phase 4

Decolonization to Reduce After-Surgery Events of Surgical Site Infection

NCT05586776

RECRUITING NA

Acupuncture Therapy and Hypertension

NCT05530512

RECRUITING

De-escalated Radiation for Human Papillomavirus-Positive Squamous Cell Carcinoma of the Oropharynx

NCT05600842

RECRUITING NA

Pilot Comparing ctDNA IDV vs. SPV Sample in Pts Undergoing Biopsies for Hepatobiliary and Pancreatic Cancers

NCT05497531

RECRUITING NA

Imaging-based Assessment of Oral Biofilm and Gingival Health

NCT05470023

RECRUITING Phase 2

Anastrazole, Fulvestrant & Abemaciclib for HR+HER2- Metastatic Breast Cancer

NCT05524584

RECRUITING Phase 4

Treatment of Meniere's Disease With Migraine Medications

NCT05582837

RECRUITING NA

Using Nicotine to Reverse Age-related Auditory Processing Deficits

NCT04971954

RECRUITING Phase 1

An Optimal Dose Finding Study of N-Acetylcysteine in Patients With Myeloproliferative Neoplasms

NCT05123365

RECRUITING Early Phase 1

Micro/Nanobubbles (MNBs) for Treatment of Acute and Chronic Wounds

NCT05169814

RECRUITING NA

Effects of Mouthrinse on the Microbiome of the Oral Cavity and GI Tract

NCT05603650

RECRUITING Phase 1

Study of ctDNA Guided Change in Tx for Refractory Minimal Residual Disease in Colon Adenocarcinomas

NCT04920032

RECRUITING NA

Dementia Family Caregiver Study

NCT04894006

RECRUITING

Spectroscopic Evaluation of Middle Ear Infection

NCT04812093

RECRUITING NA

Exercise in Child Health

NCT05359991

RECRUITING Phase 4

Anticoagulation Profile in Pregnant Women Treated With Three Times a Day of Low Molecular Weight Heparin (LMWH)

NCT04861103

RECRUITING Phase 2

Cabozantinib Combined With Ipilimumab/Nivolumab and TACE in Patients With Hepatocellular Carcinoma

NCT04472767

RECRUITING NA

A Randomized Controlled Trial of Thyroid Hormone Supplementation in Hemodialysis Patients

NCT03977207

RECRUITING Phase 4

Treatment of Tinnitus With Migraine Medications

NCT04404439

RECRUITING Phase 3

Biomarker Exploration in Aging, Cognition and Neurodegeneration

NCT03860857

RECRUITING

Pilot Study on In-vivo Non-invasive Skin Imaging Using Multiphoton Microscopy

NCT01771718

RECRUITING

A Pilot Study to Evaluate Multi-Spectral and Laser Speckle Imaging and Multiphoton Microscopy During Vascular Occlusion

NCT01484730

RECRUITING

Characterization of Familial Myopathy and Paget Disease of Bone

NCT01166854

RECRUITING

Ability of Modulated Imaging and Laser Speckle Imaging to Determine Burn Wound Severity and Healing Potential

NCT01166893

RECRUITING

Role of Angiogenesis in Dermatologic Diseases: A Potential Therapeutic Target

NCT00842283

RECRUITING

Characterization of Inclusion Body Myopathy Associated With Paget's Disease of Bone and Frontotemporal Dementia (IBMPFD)

NCT01353430

RECRUITING NA

Effect of Electro-Acupuncture on Blood Pressure

NCT00932139

ACTIVE NOT RECRUITING Phase 4

Management of Acute Tinnitus With Migraine Medications

NCT06799169

ACTIVE NOT RECRUITING NA

Scientific Information and Beliefs About Psychological Therapy

NCT06825000

ACTIVE NOT RECRUITING NA

Relaxation Music for Chronic Pain

NCT06993272

ACTIVE NOT RECRUITING NA

Health Questionnaire Study

NCT06956378

ACTIVE NOT RECRUITING NA

Youth Nominated Support Team

NCT05558332

ACTIVE NOT RECRUITING NA

Electroacupuncture in Symptom Management After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy

NCT06340906

ACTIVE NOT RECRUITING NA

Addressing Financial and Social Needs Among Patients With Cancer

NCT06430840

ACTIVE NOT RECRUITING Phase 4

Adherence to Vaginal Estrogen Therapy in Hypoestrogenic Women With Recurrent Urinary Tract Infections

NCT06353269

ACTIVE NOT RECRUITING Phase 2

Caffeine Use in the Management of Preterm Infants

NCT06327152

ACTIVE NOT RECRUITING NA

Empowering Hispanic Patients' Lung Cancer Screening Uptake (Empower Latinx)

NCT06225414

ACTIVE NOT RECRUITING NA

Pelvic Floor Physical Therapy to Reduce Stress Urinary Incontinence After Holmium Laser Enucleation of the Prostate

NCT06209307

ACTIVE NOT RECRUITING NA

Music Genre Stereotypes to Boost Relaxation in Chronic Pain Patients

NCT05979103

ACTIVE NOT RECRUITING NA

Jazz Music and Mindfulness for Chronic Pain

NCT05979012

ACTIVE NOT RECRUITING NA

Skills-Based Educational Strategies for Reduction of Vascular Events in Orange County

NCT05641519

ACTIVE NOT RECRUITING Early Phase 1

Immunotherapy Combined With Radiotherapy for Metastatic Sarcoma

NCT05488366

ACTIVE NOT RECRUITING Phase 1

Genetically Engineered Natural Killer (NK) Cells With or Without Atezolizumab for the Treatment of Non-small Cell Lung Cancer Previously Treated With PD-1 and/or PD-L1 Immune Checkpoint Inhibitors

NCT05334329

ACTIVE NOT RECRUITING NA

Determinants of the Effectiveness of Robot-assisted Hand Movement Training

NCT04818073

ACTIVE NOT RECRUITING NA

Electroacupuncture for the Management of Symptom Clusters in Cancer Patients and Survivors

NCT05283577

ACTIVE NOT RECRUITING

Sporadic Inclusion Body Myositis Natural History Study

NCT05046821

ACTIVE NOT RECRUITING Phase 1

Study of Cabozantinib Plus TAS102 in mCRC as Salvage Therapy

NCT04868773

ACTIVE NOT RECRUITING NA

Adapting the HOPE Online Support Intervention to Increase Uptake of Medications for Opioid Use Disorder

NCT04712981

ACTIVE NOT RECRUITING Phase 2

Study of Sequential Systemic Therapy + Intraperitoneal Paclitaxel in Gastric/GEJ Peritoneal Carcinomatosis

NCT04762953

ACTIVE NOT RECRUITING NA

Continuous Monitoring and Management of Vaginal Health Via Multifunctional OCT/OCTA/OCE Endoscopy

NCT04737616

ACTIVE NOT RECRUITING Phase 2

CPX-351 and Glasdegib for Newly Diagnosed Acute Myelogenous Leukemia With MDS Related Changes or Therapy-related Acute Myeloid Leukemia

NCT04231851

ACTIVE NOT RECRUITING Phase 2

Ph II Study of Cabozantinib With Pembrolizumab in Metastatic Gastric and Gastroesophageal Adenocarcinoma

NCT04164979

ACTIVE NOT RECRUITING Phase 2

Pilot Study of Mirtazapine for the Dual Tx of Depression and CINV in High-Grade Glioma Pts on TMZ

NCT03935685

ACTIVE NOT RECRUITING NA

Baby's First Years

NCT03593356

ACTIVE NOT RECRUITING NA

Acoustic and Electrical Stimulation for the Treatment of Tinnitus

NCT03511807

ACTIVE NOT RECRUITING Phase 2

Phase II Breast Ca Carboplatin + Paclitaxel With Pertuzumab + Trastuzumab or Bevacizumab

NCT02436993

ACTIVE NOT RECRUITING

Skin Imaging With Technologies in Development

NCT00764920

COMPLETED NA

Feasibility and Preliminary Effects of Fasting-Mimicking Diet in Asian Americans With Prediabetes

NCT06518798

Phase Distribution

PhaseTrial count
Phase 1 21
Phase 2 18
Phase 3 2
Phase 4 11

What the Pipeline for University of California, Irvine Shows

According to the ClinicalTrials.gov registry, University of California, Irvine is linked to 353 US clinical trials across every stage of research activity. Of those, 266 studies are currently recruiting — about 75% of the sponsor's indexed portfolio — and 57 are already marked complete, representing roughly 16% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

The phase mix for University of California, Irvine reports 13 late-stage studies (Phase 3 and Phase 4 combined) and 39 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

The top therapeutic focus area indexed for University of California, Irvine is Cancer with 6 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial