University of California, Irvine
Trial Pipeline
Resilience in Reentry: Cognitive-Behavioral Resilience Training for Parolees With Adjustment Challenges
NCT07167719
Riluzole For Preventing Cognitive Dysfunction in Ca Pts Receiving Chemo (REFOCUS): Pilot Trial
NCT07447050
HOPE Intervention for Fitness
NCT07114822
Telemedicine to Support Living Kidney Donor Candidates
NCT07206069
Treating Anemia in Myelofibrosis With Repurposed Drugs (Nelfinavir) That Restore Iron Delivery to the Bone Marrow
NCT07281781
Mapping Ibogaine Neural Dynamics in Opioid Use Disorder
NCT07226570
Mobile Health Intervention to Improve Adherence to Oral Anticancer Therapy
NCT07073807
Wearable Device and Behavioral Support for Enhancing Arm Use After Stroke
NCT07042152
EndoPAT Device for Endothelial Dysfunction in ED
NCT06720597
Response Adapted Neoadjuvant Therapy in Gastroesophageal Cancers (RANT-GC Trial)
NCT05733689
Lung Cancer Screening of Family Members of Patients With Mutation-Driven Lung Cancer
NCT07062172
Impact of Sodium Bicarbonate on 24-hour Urine Parameters in Hypocitriuric and Uric Acid Stone Formers
NCT06335537
Trial of Single Protein Encapsulated Doxorubicin, SPEDOX-6 in Advanced Malignancies
NCT07064018
The THRIVE Study: Teaching Healthy Regulation in Individuals & Vulnerable Environments
NCT06821035
MULTIsite Feasibility of MUSIc Therapy to Address Quality Of Life in Sickle Cell Disease
NCT06853158
Conscious Pregnancy: Supporting Maternal Cardiometabolic Health With Mindfulness
NCT06898658
Mechanistic and Clinical Outcomes of a Surgical Innovation Aimed at Minimizing GERD Associated With VSG (INNOVATE-VSG)
NCT06783751
Analgesic Response to Opioids in Patients With Fibromyalgia After Conventional Acupuncture Versus Sham Acupuncture
NCT06571110
My Life and My Experiences Project
NCT06821178
Metronomic Cyclophosphamide With Pembrolizumab in Checkpoint Inhibitor Refractory Melanoma
NCT06771544
Single-Center Eval of Clinical & Radiological Benefit AHCC in Combo W/ SOC Tx for HPV+ Pts W/ HNSCC
NCT06693323
The Effects of Energy Healing in Fibromyalgia
NCT06552728
Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial
NCT06580002
Adjuvant Sacituzumab Govitecan and Nivolumab in Muscle-Invasive Urothelial Carcinoma At High-Risk Recurrence
NCT06682728
PhI Pilot Study Pafolacianine Inject for Intraoperative Imaging on Outcomes of GI Cancer Peritoneal Carcinomatosis
NCT06511037
The Effects of Core Shamanism in Fibromyalgia
NCT06579261
Impact of Intraoperative ICG on Functional Outc in RARP
NCT06446648
CMV-TCIP Directed Letermovir Prophylaxis After Allo-SCT
NCT06453460
A Biobehavioral Intervention for Latino/Hispanic Young Adults with Cancer
NCT06338475
Neuromuscular Blockade Comparison for GI-2 Recovery After Bowel Resection
NCT06112353
mpMRI Compared to Diagnostic TURBT in Patients With Suspected Muscle-Invasive Bladder Cancer
NCT06335667
Effect of Fasting on Patient Outcomes After Wide-Awake, Local Anesthesia-only, No Tourniquet (WALANT) Procedures
NCT05819801
Positive Affect Treatment for Adolescents with Early Life Adversity
NCT06273137
Assess Diversity of Gut Microbiome in Met NSCLC in Correlation to Tx & Adverse Effects
NCT06221800
Impact of Personality on Adherence to Tyrosine Kinase Inhibitor Therapy in Pts w/Chronic Myeloid Leukemia
NCT06229860
Shorter Versus Extended Course of Antibiotic Therapy for Necrotizing Soft Tissue Infections
NCT06002607
A Biobehavioral Intervention to Reduce Adverse Outcomes in Young Adult Testicular Cancer Survivors
NCT05836688
Risk-ADAPTed Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation
NCT06028828
Pharmacotherapy in Conjunction With Lifestyle Counseling for Management of Weight Regain After Bariatric Surgery
NCT05975580
Latinx Children and Surgery
NCT06020677
Patient Derived Vascularized MicroTumor Model of Gastrointestinal Peritoneal Carcinomatosis
NCT05844865
Vaginal Changes After CO2 Laser
NCT06691178
Decolonization to Reduce After-Surgery Events of Surgical Site Infection
NCT05586776
Acupuncture Therapy and Hypertension
NCT05530512
De-escalated Radiation for Human Papillomavirus-Positive Squamous Cell Carcinoma of the Oropharynx
NCT05600842
Pilot Comparing ctDNA IDV vs. SPV Sample in Pts Undergoing Biopsies for Hepatobiliary and Pancreatic Cancers
NCT05497531
Imaging-based Assessment of Oral Biofilm and Gingival Health
NCT05470023
Anastrazole, Fulvestrant & Abemaciclib for HR+HER2- Metastatic Breast Cancer
NCT05524584
Treatment of Meniere's Disease With Migraine Medications
NCT05582837
Using Nicotine to Reverse Age-related Auditory Processing Deficits
NCT04971954
An Optimal Dose Finding Study of N-Acetylcysteine in Patients With Myeloproliferative Neoplasms
NCT05123365
Micro/Nanobubbles (MNBs) for Treatment of Acute and Chronic Wounds
NCT05169814
Effects of Mouthrinse on the Microbiome of the Oral Cavity and GI Tract
NCT05603650
Study of ctDNA Guided Change in Tx for Refractory Minimal Residual Disease in Colon Adenocarcinomas
NCT04920032
Dementia Family Caregiver Study
NCT04894006
Spectroscopic Evaluation of Middle Ear Infection
NCT04812093
Exercise in Child Health
NCT05359991
Anticoagulation Profile in Pregnant Women Treated With Three Times a Day of Low Molecular Weight Heparin (LMWH)
NCT04861103
Cabozantinib Combined With Ipilimumab/Nivolumab and TACE in Patients With Hepatocellular Carcinoma
NCT04472767
A Randomized Controlled Trial of Thyroid Hormone Supplementation in Hemodialysis Patients
NCT03977207
Treatment of Tinnitus With Migraine Medications
NCT04404439
Biomarker Exploration in Aging, Cognition and Neurodegeneration
NCT03860857
Pilot Study on In-vivo Non-invasive Skin Imaging Using Multiphoton Microscopy
NCT01771718
A Pilot Study to Evaluate Multi-Spectral and Laser Speckle Imaging and Multiphoton Microscopy During Vascular Occlusion
NCT01484730
Characterization of Familial Myopathy and Paget Disease of Bone
NCT01166854
Ability of Modulated Imaging and Laser Speckle Imaging to Determine Burn Wound Severity and Healing Potential
NCT01166893
Role of Angiogenesis in Dermatologic Diseases: A Potential Therapeutic Target
NCT00842283
Characterization of Inclusion Body Myopathy Associated With Paget's Disease of Bone and Frontotemporal Dementia (IBMPFD)
NCT01353430
Effect of Electro-Acupuncture on Blood Pressure
NCT00932139
Management of Acute Tinnitus With Migraine Medications
NCT06799169
Scientific Information and Beliefs About Psychological Therapy
NCT06825000
Relaxation Music for Chronic Pain
NCT06993272
Health Questionnaire Study
NCT06956378
Youth Nominated Support Team
NCT05558332
Electroacupuncture in Symptom Management After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy
NCT06340906
Addressing Financial and Social Needs Among Patients With Cancer
NCT06430840
Adherence to Vaginal Estrogen Therapy in Hypoestrogenic Women With Recurrent Urinary Tract Infections
NCT06353269
Caffeine Use in the Management of Preterm Infants
NCT06327152
Empowering Hispanic Patients' Lung Cancer Screening Uptake (Empower Latinx)
NCT06225414
Pelvic Floor Physical Therapy to Reduce Stress Urinary Incontinence After Holmium Laser Enucleation of the Prostate
NCT06209307
Music Genre Stereotypes to Boost Relaxation in Chronic Pain Patients
NCT05979103
Jazz Music and Mindfulness for Chronic Pain
NCT05979012
Skills-Based Educational Strategies for Reduction of Vascular Events in Orange County
NCT05641519
Immunotherapy Combined With Radiotherapy for Metastatic Sarcoma
NCT05488366
Genetically Engineered Natural Killer (NK) Cells With or Without Atezolizumab for the Treatment of Non-small Cell Lung Cancer Previously Treated With PD-1 and/or PD-L1 Immune Checkpoint Inhibitors
NCT05334329
Determinants of the Effectiveness of Robot-assisted Hand Movement Training
NCT04818073
Electroacupuncture for the Management of Symptom Clusters in Cancer Patients and Survivors
NCT05283577
Sporadic Inclusion Body Myositis Natural History Study
NCT05046821
Study of Cabozantinib Plus TAS102 in mCRC as Salvage Therapy
NCT04868773
Adapting the HOPE Online Support Intervention to Increase Uptake of Medications for Opioid Use Disorder
NCT04712981
Study of Sequential Systemic Therapy + Intraperitoneal Paclitaxel in Gastric/GEJ Peritoneal Carcinomatosis
NCT04762953
Continuous Monitoring and Management of Vaginal Health Via Multifunctional OCT/OCTA/OCE Endoscopy
NCT04737616
CPX-351 and Glasdegib for Newly Diagnosed Acute Myelogenous Leukemia With MDS Related Changes or Therapy-related Acute Myeloid Leukemia
NCT04231851
Ph II Study of Cabozantinib With Pembrolizumab in Metastatic Gastric and Gastroesophageal Adenocarcinoma
NCT04164979
Pilot Study of Mirtazapine for the Dual Tx of Depression and CINV in High-Grade Glioma Pts on TMZ
NCT03935685
Baby's First Years
NCT03593356
Acoustic and Electrical Stimulation for the Treatment of Tinnitus
NCT03511807
Phase II Breast Ca Carboplatin + Paclitaxel With Pertuzumab + Trastuzumab or Bevacizumab
NCT02436993
Skin Imaging With Technologies in Development
NCT00764920
Feasibility and Preliminary Effects of Fasting-Mimicking Diet in Asian Americans With Prediabetes
NCT06518798
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 21 |
| Phase 2 | 18 |
| Phase 3 | 2 |
| Phase 4 | 11 |
Therapeutic Areas
What the Pipeline for University of California, Irvine Shows
According to the ClinicalTrials.gov registry, University of California, Irvine is linked to 353 US clinical trials across every stage of research activity. Of those, 266 studies are currently recruiting — about 75% of the sponsor's indexed portfolio — and 57 are already marked complete, representing roughly 16% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
The phase mix for University of California, Irvine reports 13 late-stage studies (Phase 3 and Phase 4 combined) and 39 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
The top therapeutic focus area indexed for University of California, Irvine is Cancer with 6 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology — how this data is sourced, computed, and verified.