Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT01642277 · ClinicalTrials.gov registry record · Phase 2
Bacterial Genomic Sequencing in Overactive Bladder
A Phase 2 study of Overactive Bladder, sponsored by Loyola University.
- Completed
- Registry status
- Phase 2
- Development phase
- 134
- Enrollment target
- 1
- Study location
NCT01642277 is a Phase 2 study of Overactive Bladder that has completed, run by Loyola University. The registered enrollment target is 134 participants, below the 209-participant average among 45 other Overactive Bladder trials with a reported enrollment target (36% lower). The trial reports 1 study location across 1 state.
The verdict
NCT01642277, a Phase 2 study of Overactive Bladder, has completed, sponsored by Loyola University.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 134 participants
- Enrollment target
- 1
- Study location
Study Summary
No one really knows what causes overactive bladder syndrome (OAB). Urinary tract infection (UTI)causes similar symptoms to OAB with the difference being the presence of bacteria, as evidenced by routine microbiology cultures. Recent work by the group on the genitourinary microbiome (GUM) has shown that female urine, even in the absence of culture evidence of bacteria does have evidence of bacterial DNA. Bacterial 16S rRNA can be isolated from urine and sequenced to identify bacterial species present in urine. From this the investigators can hypothesize that urinary bacteria contribute to urinary symptoms and that there is a difference in the bacterial communities in the urine of women who respond to Solifenacin, a drug used to treat OAB, versus those that do not.
Conditions Studied
Interventions
- DRUG Solifenacin
Study Locations (1)
Illinois
- Loyola University Chicago Health Sciences Division - Maywood
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 134 participants |
| Start Date | 2012-07 |
| Est. Completion | 2014-08 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01642277
The ClinicalTrials.gov registry entry for NCT01642277 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 134 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 209-participant average among 45 other Overactive Bladder trials with a reported enrollment target (36% lower). The listed sponsor is Loyola University, which has 92 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Overactive Bladder appearing as the primary indexed condition, and to 1 intervention - of which Solifenacin is the first listed.
NCT01642277 reports 1 study location spanning 1 distinct geographic area - top geographies include Illinois.
Frequently Asked Questions
What is clinical trial NCT01642277 about?
NCT01642277 is a clinical study titled "Bacterial Genomic Sequencing in Overactive Bladder". No one really knows what causes overactive bladder syndrome (OAB). Urinary tract infection (UTI)causes similar symptoms to OAB with the difference being the presence of bacteria, as evidenced by routine microbiology cultures. Recent work by the group on the genitourinary microbiome (GUM) has shown t...
What is the current status of trial NCT01642277?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 134 participants. The study started on 2012-07. Estimated completion is 2014-08.
What conditions does trial NCT01642277 study?
This clinical trial studies the following conditions: Overactive Bladder.
What interventions are being tested in trial NCT01642277?
The interventions under investigation include: Solifenacin (DRUG).
Who is sponsoring clinical trial NCT01642277?
This trial is sponsored by Loyola University, which has 92 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01642277 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Overactive Bladder
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Examining the Effects of Intra-detrusor Botox at Time of HoLEP in Men With Overactive Bladder Symptoms
RECRUITING · Phase 2
-
Two Phase Extension Trial of SP668 to Investigate the Safety and Tolerability of Sustained Release Fesoterodine in Subjects With Overactive Bladder: a Double-Blind Phase Followed by an Open-Label Extension Phase
COMPLETED · Phase 2
-
A Study to Evaluate Once Daily Low Dose and High Dose Solabegron or Placebo Given for 12 Weeks to Treat Women With Symptoms of Overactive Bladder: Sudden Urge to Urinate, Frequent Urination Associated With Wetting Episodes (VEL-2001)
COMPLETED · Phase 2
-
Combined Behavioral and Drug Treatment of Overactive Bladder in Men
COMPLETED · Phase 2
-
Home Versus Office Removal of Percutaneous Nerve Evaluation (PNE) Lead
RECRUITING · NA
-
Bladder Botox UTI Antibiotic Prophylaxis
RECRUITING · Phase 4
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.