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NCT05878951 · ClinicalTrials.gov registry record · Phase 2
Examining the Effects of Intra-detrusor Botox at Time of HoLEP in Men With Overactive Bladder Symptoms
A Phase 2 study of Urinary Incontinence and Overactive Bladder, sponsored by Northwestern University.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 80
- Enrollment target
- 1
- Study location
NCT05878951: Recruiting Phase 2 study of Urinary Incontinence and Overactive Bladder, sponsored by Northwestern University.
NCT05878951 is a Phase 2 study of Urinary Incontinence and Overactive Bladder that is actively recruiting participants, run by Northwestern University. The registered enrollment target is 80 participants, below the 260-participant average among 48 other Urinary Incontinence trials with a reported enrollment target (69% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05878951, a Phase 2 study of Urinary Incontinence and Overactive Bladder, is actively recruiting participants, sponsored by Northwestern University.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 80 participants
- Enrollment target
- 1
- Study location
Study Summary
The objective of our multi-center randomized single-blind study is to examine the safety and effect of intra-detrusor OnabotulinumtoxinA injections at the time of holium laser enucleation of the prostate (HoLEP) in men with overactive bladder symptoms with and without urge incontinence.
Primary Outcome
Examine the safety and effect of intra-detrusor botulinum toxin injections at the time of helium laser enucleation of the prostate (HoLEP) in men with overactive bladder symptoms with and without urge incontinence.
Conditions Studied
Interventions
- DRUG OnabotulinumtoxinA
Study Locations (1)
Illinois
- Northwestern Medicine - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2023-07-13 |
| Est. Completion | 2026-08-24 |
| Phase | Phase 2 |
What NCT05878951 shows while recruiting
NCT05878951 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 260-participant average among 48 other Urinary Incontinence trials with a reported enrollment target (69% lower).
The record links to 4 conditions, with Urinary Incontinence appearing as the primary indexed condition, and to 1 intervention - of which OnabotulinumtoxinA is the first listed.
NCT05878951 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT05878951 about?
NCT05878951 is a clinical study titled "Examining the Effects of Intra-detrusor Botox at Time of HoLEP in Men With Overactive Bladder Symptoms". The objective of our multi-center randomized single-blind study is to examine the safety and effect of intra-detrusor OnabotulinumtoxinA injections at the time of holium laser enucleation of the prostate (HoLEP) in men with overactive bladder symptoms with and without urge incontinence.
What is the current status of trial NCT05878951?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 80 participants. The study started on 2023-07-13. Estimated completion is 2026-08-24.
What conditions does trial NCT05878951 study?
This clinical trial studies the following conditions: Urinary Incontinence, Overactive Bladder, Overactive Bladder Syndrome, Urologic Diseases.
What interventions are being tested in trial NCT05878951?
The interventions under investigation include: OnabotulinumtoxinA (DRUG).
Who is sponsoring clinical trial NCT05878951?
This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05878951 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Urinary Incontinence
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05878951's enrollment target sits among peer trials
80 27th of 48 higher than 22 of 48 other Urinary Incontinence trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Urinary Incontinence trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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