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NCT06198439 · ClinicalTrials.gov registry record · NA
rTMS in Overactive Bladder
A NA study of Urinary Incontinence and Overactive Bladder, sponsored by The Methodist Hospital Research Institute.
- Recruiting
- Registry status
- NA
- Development phase
- 10
- Enrollment target
- 1
- Study location
NCT06198439 is a NA study of Urinary Incontinence and Overactive Bladder that is actively recruiting participants, run by The Methodist Hospital Research Institute. The registered enrollment target is 10 participants, below the 262-participant average among 48 other Urinary Incontinence trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06198439, a NA study of Urinary Incontinence and Overactive Bladder, is actively recruiting participants, sponsored by The Methodist Hospital Research Institute.
- RECRUITING
- Registry status
- NA
- Development phase
- 10 participants
- Enrollment target
- 1
- Study location
Study Summary
Overactive bladder (OAB) imposes a significant quality of life, mental health, and economic burdens. OAB with or without Urgency incontinence is associated with depression, sexual dysfunction, and limitation of social interactions and physical activities, which significantly affects quality of life. Non-invasive neuromodulation with repetitive transcranial magnetic stimulation (rTMS) can be used in research settings to investigate responses to focal regional brain activation. In the clinical setting, rTMS normalizes brain activity with associated clinical benefits in conditions such as refractory depression. rTMS has been studied for effects on lower urinary tract symptoms (LUTS) in bladder pain and neurogenic lower urinary tract symptoms (LUTS) populations. Unlike many standard of care OAB interventions, the safety of rTMS is well-reported, including for use in elderly populations and those with cognitive impairment. Functional magnetic resonance imaging (fMRI) to evaluate neuroplasticity is emerging as an essential tool to define OAB phenotypes; however, phenotyping studies guided by mechanistic data are lacking. The effects of central neuromodulation on regions involved OAB mechanisms and associated physiological and clinical responses are unknown. This study will be the first to report neuroplasticity, physiologic, and clinical effects of central neuromodulation with rTMS in adults with OAB.
Conditions Studied
Interventions
- DEVICE Transcranial Magnetic Stimulation
Study Locations (1)
Texas
- Houston Methodist Hospital - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2024-01-08 |
| Est. Completion | 2026-07 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06198439
The ClinicalTrials.gov registry entry for NCT06198439 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 10 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 262-participant average among 48 other Urinary Incontinence trials with a reported enrollment target (96% lower). The listed sponsor is The Methodist Hospital Research Institute, which has 126 total studies on file at ClinicalTrials.gov.
The record links to 6 conditions, with Urinary Incontinence appearing as the primary indexed condition, and to 1 intervention - of which Transcranial Magnetic Stimulation is the first listed.
NCT06198439 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.
Frequently Asked Questions
What is clinical trial NCT06198439 about?
NCT06198439 is a clinical study titled "rTMS in Overactive Bladder". Overactive bladder (OAB) imposes a significant quality of life, mental health, and economic burdens. OAB with or without Urgency incontinence is associated with depression, sexual dysfunction, and limitation of social interactions and physical activities, which significantly affects quality of life....
What is the current status of trial NCT06198439?
This trial is currently recruiting. It is a NA study. The enrollment target is 10 participants. The study started on 2024-01-08. Estimated completion is 2026-07.
What conditions does trial NCT06198439 study?
This clinical trial studies the following conditions: Urinary Incontinence, Overactive Bladder, Overactive Bladder Syndrome, Urinary Incontinence, Urge, Urge Incontinence.
What interventions are being tested in trial NCT06198439?
The interventions under investigation include: Transcranial Magnetic Stimulation (DEVICE).
Who is sponsoring clinical trial NCT06198439?
This trial is sponsored by The Methodist Hospital Research Institute, which has 126 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06198439 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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