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ClinicalTrials.gov 88 recruiting now early-phase tilt #21 of 28,707 conditions

Lymphoma: early-phase trial registry

88 of 330 indexed Lymphoma trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #21 of 28,707 conditions by registered trial count.

330 US clinical trials · 88 currently recruiting · #21 of 28,707 conditions by registered trial count

Lymphoma: 330 US clinical trials tracked, 88 recruiting.

Lymphoma is the subject of 330 registered US clinical trials on ClinicalTrials.gov, 88 of them currently open to new participants. 25 are in Phase 3-4 (later-stage) and 229 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 34 of these trials.

Enrollment posture brief

Registry condition lymphoma

OPEN 88 | RECR 27% | LATE 25 | EARLY 229 | RANK #21 | SPON 34

Nearest open-share peer: Age-related Macular Degeneration (27% recruiting · 75 trials)

Ovarian Cancer43.5%Type 2 Diabetes36.6%Lymphoma (this)27%Diabetes25.1%Schizophrenia23.9%
Open-enrollment share among volume-matched conditions near Lymphoma

Lymphoma lists 88 open slots (27% of 330 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Lymphoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Lymphoma is recruiting below its size-band peers.

    88 of 330 indexed trials (26.7%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Lymphoma trials is spread across many organizations.

    Memorial Sloan Kettering Cancer Center accounts for 34 of 330 trials (10.3%). 116 distinct sponsors appear on at least one study for this condition label.

  3. Most Lymphoma trials plan to enrol fewer than 100 people.

    Median target enrolment is 50 among the 300 trials that report a genuine target (sentinel values excluded). 213 of those (71%) plan for fewer than 100 participants.

  4. Lymphoma research is mostly interventional.

    299 interventional and 31 observational studies make up this index (90.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 1119Phase 2110Phase 322Phase 43

Open and recent trials

330 total, page 5 of 7

COMPLETED Phase 2 68 participants

Pentostatin, Cyclophosphamide, and Rituximab With or Without Bevacizumab in Treating Patients With B-Cell Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Mayo Clinic

NCT00816595

COMPLETED Phase 2 68 participants

Donor Stem Cell Transplant in Treating Patients With High-Risk Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Alliance for Clinical Trials in Oncology

NCT01027000

COMPLETED NA 65 participants

Safety and Efficacy of Campath in Nonmyeloablative Transplantation

M.D. Anderson Cancer Center

NCT00038844

COMPLETED Phase 1 61 participants

Aza-SAHA-GBM With AutoSCT for Refractory Lymphoma

M.D. Anderson Cancer Center

NCT01983969

COMPLETED Phase 3 61 participants

Combination Chemotherapy in Treating Patients With Intermediate-Grade or Immunoblastic Non-Hodgkin's Lymphoma

M.D. Anderson Cancer Center

NCT00002565

COMPLETED 61 participants

Evaluation of Loratadine for G-CSF Induced Bone Pain in Patients With Hematologic Malignancies

Wake Forest University Health Sciences

NCT02305979

COMPLETED Phase 2 60 participants

A Phase 2 Safety and Efficacy Study of INCB050465 in Subjects With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (CITADEL-202)

Incyte Corporation

NCT02998476

COMPLETED 60 participants

The Effects of Anthracycline-based Chemotherapy on Peripheral Vascular Function

Carl Ade, M.S., Ph.D.

NCT03062878

COMPLETED Phase 2 60 participants

Thiotepa-Clofarabine-Busulfan With Allogeneic Stem Cell Transplant for High Risk Malignancies

M.D. Anderson Cancer Center

NCT00857389

COMPLETED NA 59 participants

A Novel Health Information Technology System (BMT Roadmap) for Pediatric BMT Patients and Caregivers

University of Michigan Rogel Cancer Center

NCT02409121

COMPLETED Phase 1 57 participants

Pralatrexate + Romidepsin in Relapsed/Refractory Lymphoid Malignancies

Jennifer Amengual

NCT01947140

COMPLETED Phase 2 57 participants

Study of AP23573 in Patients With Relapsed or Refractory Hematologic Malignancies (8669-024)(COMPLETED)

Merck Sharp & Dohme

NCT00086125

COMPLETED Phase 1 55 participants

Safety, Tolerability and Pharmacokinetic (PK) of Concomitant Esomeprazole and Rifampin, and QT Study on Single and Multiple-doses of Alisertib

Millennium Pharmaceuticals

NCT01844583

COMPLETED Phase 2 53 participants

Alemtuzumab and Glucocorticoids in Treating Newly Diagnosed Acute Graft-Versus-Host Disease in Patients Who Have Undergone a Donor Stem Cell Transplant

Fred Hutchinson Cancer Center

NCT00410657

COMPLETED Phase 2 51 participants

Ofatumumab in Treating Patients With Previously Untreated Stage II, Stage III, or Stage IV Follicular Non-Hodgkin Lymphoma

Alliance for Clinical Trials in Oncology

NCT01190449

COMPLETED Phase 2 51 participants

Cladribine in Patients With Mantle Cell Lymphoma

Alliance for Clinical Trials in Oncology

NCT00002879

COMPLETED Phase 2 50 participants

Chemotherapy Plus Radiation Therapy and Biological Therapy in Treating Patients With Hematologic Cancer

Fred Hutchinson Cancer Center

NCT00002553

COMPLETED Phase 1 50 participants

Pentostatin, Cyclophosphamide, Rituximab, and Mitoxantrone in Treating Patients With Chronic Lymphocytic Leukemia or Other Low-Grade B-Cell Cancer

Memorial Sloan Kettering Cancer Center

NCT00546377

COMPLETED Phase 2 50 participants

Denileukin Diftitox in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma

Jonsson Comprehensive Cancer Center

NCT00138164

COMPLETED Phase 2 48 participants

Allo Non-myeloablative SCT Utilizing Matched Family Member Stem Cells Purged Using Campath

David Rizzieri, MD

NCT00578942

COMPLETED Phase 2 47 participants

Rituximab and Combination Chemotherapy in Treating Patients With Newly Diagnosed Primary CNS Lymphoma

Alliance for Clinical Trials in Oncology

NCT00098774

COMPLETED NA 45 participants

Evaluating the Feasibility of a Digital Health Coaching Program for Individuals Following CAR T Therapy

Pack Health

NCT05064787

COMPLETED Phase 4 45 participants

Bone Marrow Transplantation in Treating Patients With Hematologic Cancer

University of Maryland, Baltimore

NCT00003398

COMPLETED Phase 1 44 participants

Radiolabeled Monoclonal Antibody Therapy and High-Dose Chemotherapy Followed By Autologous Peripheral Stem Cell Transplant in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma

Northwestern University

NCT00058292

COMPLETED Phase 2 42 participants

Autologous Stem Cell Transplant in Treating Patients With Progressive or Recurrent Hodgkin's Lymphoma

Case Comprehensive Cancer Center

NCT00265889

COMPLETED Phase 1 41 participants

T-Regulatory Cell Infusion Post Umbilical Cord Blood Transplant in Patients With Advanced Hematologic Cancer

Masonic Cancer Center, University of Minnesota

NCT00602693

COMPLETED Phase 1 40 participants

Total Body Irradiation With Fludarabine Followed by Combined Umbilical Cord Blood (UCB) Transplants

Duke University

NCT00606437

COMPLETED Phase 2 39 participants

Rituximab in Treating Patients With Non-Hodgkin's Lymphoma or Hodgkin's Disease

Alliance for Clinical Trials in Oncology

NCT00003849

COMPLETED Phase 2 39 participants

Rituximab in Treating Patients With Hodgkin's Lymphoma

Ranjana Advani

NCT00003820

COMPLETED NA 39 participants

Donor Lymphocyte Infusion in Treating Patients With Recurrent or Persistent Hematologic Cancer After Donor Stem Cell Transplant

Roswell Park Cancer Institute

NCT00534118

COMPLETED NA 37 participants

Exercise Program for Adolescents and Young Adults With Cancer

M.D. Anderson Cancer Center

NCT00502749

COMPLETED 36 participants

Long-Term Effects of Iodine I Tositumomab and Autologous Bone Marrow or Stem Cell Transplantation in Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma

Fred Hutchinson Cancer Center

NCT00098566

COMPLETED Phase 2 35 participants

Ixabepilone in Treating Patients With Relapsed or Refractory Lymphoproliferative Disorders

Memorial Sloan Kettering Cancer Center

NCT00052572

COMPLETED Phase 2 35 participants

Gallium Nitrate in Treating Patients With AIDS-Related Non-Hodgkin's Lymphoma

Roswell Park Cancer Institute

NCT00002578

COMPLETED Phase 2 35 participants

506U78 in Treating Patients With Refractory or Relapsed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

National Cancer Institute (NCI)

NCT00003545

COMPLETED Phase 1 35 participants

Study of AR-12 (2-Amino-N-[4-[5-(2 Phenanthrenyl)-3-(Trifluoromethyl)-1H-pyrazol-1-yl] Phenyl]-Acetamide) in Adult Patients With Advanced or Recurrent Solid Tumors or Lymphoma

Arno Therapeutics

NCT00978523

COMPLETED Phase 1 35 participants

VNP40101M in Treating Patients With Richter Syndrome or Refractory or Relapsed Chronic Lymphocytic Leukemia or Other Lymphoproliferative Disorders

Vion Pharmaceuticals

NCT00304005

COMPLETED Phase 2 34 participants

Rituximab and Combination Chemotherapy in Treating Patients With Newly Diagnosed, HIV-Associated Burkitt's Lymphoma

AIDS Malignancy Consortium

NCT00392834

COMPLETED Phase 2 34 participants

Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer

Case Comprehensive Cancer Center

NCT00054327

COMPLETED Phase 2 34 participants

S0350 Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage II, Stage III, or Stage IV Peripheral T-Cell Non-Hodgkin's Lymphoma

SWOG Cancer Research Network

NCT00109928

COMPLETED Phase 2 34 participants

Campath-1H + FK506 and Methylprednisolone for GVHD

Case Comprehensive Cancer Center

NCT00109993

COMPLETED Phase 2 33 participants

Lenalidomide in Treating Patients With Relapsed Mycosis Fungoides/Sezary Syndrome

Northwestern University

NCT00466921

COMPLETED Phase 1 32 participants

Study of TRPH-222 in Patients With Relapsed and/or Refractory B-Cell Lymphoma

Triphase Research and Development III

NCT03682796

COMPLETED Phase 2 32 participants

Sirolimus, Tacrolimus, and Antithymocyte Globulin in Preventing Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant For Hematological Cancer

City of Hope Medical Center

NCT00589563

COMPLETED Phase 1 32 participants

Rituxan and BEAM With Autologous Peripheral Blood Progenitor Transplant for Indolent Lymphoma

University of Nebraska

NCT00572013

COMPLETED Phase 2 32 participants

Ixazomib Rollover Study

Takeda

NCT02924272

COMPLETED 31 participants

Immune Reconstitution in Oncology Patients Following Autologous Stem Cell Transplant

St. Jude Children's Research Hospital

NCT01540175

COMPLETED Phase 2 30 participants

Galiximab in Treating Patients With Relapsed or Refractory Hodgkin's Lymphoma

Alliance for Clinical Trials in Oncology

NCT00516217

COMPLETED Early Phase 1 30 participants

Pilot Study of Non-Myeloablative, HLA-Matched Allogeneic Stem Cell Transplantation for Pediatric Hematopoietic Malignancies

National Cancer Institute (NCI)

NCT00013533

COMPLETED Phase 1 30 participants

Trial of Vorinostat in Combination With Cyclophosphamide, Etoposide, Prednisone and Rituximab for Elderly Patients With Relapsed Diffuse Large B-Cell Lymphoma (DLBCL)

Memorial Sloan Kettering Cancer Center

NCT00667615

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Phase Distribution

PhaseTrial count
Phase 1 119
Phase 2 110
Phase 3 22
Phase 4 3

Named interventions

Most-linked intervention names on Lymphoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

cyclophosphamide Drug
30 trials
rituximab Biological
26 trials
Cyclophosphamide Drug
23 trials
Rituximab Drug
21 trials
filgrastim Biological
17 trials
cytarabine Drug
14 trials
etoposide Drug
13 trials
Fludarabine Drug
13 trials

US sites by state

Facility locations filed on Lymphoma trials. A trial with sites in several states counts in each.

California 91 trials
New York 82 trials
Texas 71 trials
Maryland 50 trials
Illinois 50 trials
Massachusetts 47 trials
Florida 45 trials
North Carolina 37 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Lymphoma page

330 registered trials, 88 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Lymphoma condition card totals 330 registered trials; most-linked intervention cyclophosphamide; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.