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ClinicalTrials.gov 88 recruiting now official registry

Lymphoma clinical trials

88 of 330 indexed Lymphoma trials are currently recruiting.

330 US clinical trials · 88 currently recruiting

Lymphoma is the subject of 330 registered US clinical trials on ClinicalTrials.gov, 88 of them currently open to new participants. 25 are in Phase 3-4 (later-stage) and 229 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 34 of these trials.

The research picture

Lymphoma has 330 registered US clinical trials, 88 of them open to new participants right now, about 27% of the total.

88
recruiting participants now
27%
of trials open to enrollment
25
in Phase 3–4 (later-stage)
34
top sponsor: Memorial Sloan Kettering Cancer Center
Phase 1119Phase 2110Phase 322Phase 43

Active & Recent Trials

330 total, page 5 of 7

COMPLETED Phase 2 68 participants

Pentostatin, Cyclophosphamide, and Rituximab With or Without Bevacizumab in Treating Patients With B-Cell Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Mayo Clinic

NCT00816595

COMPLETED Phase 2 68 participants

Donor Stem Cell Transplant in Treating Patients With High-Risk Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Alliance for Clinical Trials in Oncology

NCT01027000

COMPLETED NA 65 participants

Safety and Efficacy of Campath in Nonmyeloablative Transplantation

M.D. Anderson Cancer Center

NCT00038844

COMPLETED Phase 1 61 participants

Aza-SAHA-GBM With AutoSCT for Refractory Lymphoma

M.D. Anderson Cancer Center

NCT01983969

COMPLETED Phase 3 61 participants

Combination Chemotherapy in Treating Patients With Intermediate-Grade or Immunoblastic Non-Hodgkin's Lymphoma

M.D. Anderson Cancer Center

NCT00002565

COMPLETED 61 participants

Evaluation of Loratadine for G-CSF Induced Bone Pain in Patients With Hematologic Malignancies

Wake Forest University Health Sciences

NCT02305979

COMPLETED Phase 2 60 participants

A Phase 2 Safety and Efficacy Study of INCB050465 in Subjects With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (CITADEL-202)

Incyte Corporation

NCT02998476

COMPLETED 60 participants

The Effects of Anthracycline-based Chemotherapy on Peripheral Vascular Function

Carl Ade, M.S., Ph.D.

NCT03062878

COMPLETED Phase 2 60 participants

Thiotepa-Clofarabine-Busulfan With Allogeneic Stem Cell Transplant for High Risk Malignancies

M.D. Anderson Cancer Center

NCT00857389

COMPLETED NA 59 participants

A Novel Health Information Technology System (BMT Roadmap) for Pediatric BMT Patients and Caregivers

University of Michigan Rogel Cancer Center

NCT02409121

COMPLETED Phase 1 57 participants

Pralatrexate + Romidepsin in Relapsed/Refractory Lymphoid Malignancies

Jennifer Amengual

NCT01947140

COMPLETED Phase 2 57 participants

Study of AP23573 in Patients With Relapsed or Refractory Hematologic Malignancies (8669-024)(COMPLETED)

Merck Sharp & Dohme

NCT00086125

COMPLETED Phase 1 55 participants

Safety, Tolerability and Pharmacokinetic (PK) of Concomitant Esomeprazole and Rifampin, and QT Study on Single and Multiple-doses of Alisertib

Millennium Pharmaceuticals

NCT01844583

COMPLETED Phase 2 53 participants

Alemtuzumab and Glucocorticoids in Treating Newly Diagnosed Acute Graft-Versus-Host Disease in Patients Who Have Undergone a Donor Stem Cell Transplant

Fred Hutchinson Cancer Center

NCT00410657

COMPLETED Phase 2 51 participants

Ofatumumab in Treating Patients With Previously Untreated Stage II, Stage III, or Stage IV Follicular Non-Hodgkin Lymphoma

Alliance for Clinical Trials in Oncology

NCT01190449

COMPLETED Phase 2 51 participants

Cladribine in Patients With Mantle Cell Lymphoma

Alliance for Clinical Trials in Oncology

NCT00002879

COMPLETED Phase 2 50 participants

Chemotherapy Plus Radiation Therapy and Biological Therapy in Treating Patients With Hematologic Cancer

Fred Hutchinson Cancer Center

NCT00002553

COMPLETED Phase 1 50 participants

Pentostatin, Cyclophosphamide, Rituximab, and Mitoxantrone in Treating Patients With Chronic Lymphocytic Leukemia or Other Low-Grade B-Cell Cancer

Memorial Sloan Kettering Cancer Center

NCT00546377

COMPLETED Phase 2 50 participants

Denileukin Diftitox in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma

Jonsson Comprehensive Cancer Center

NCT00138164

COMPLETED Phase 2 48 participants

Allo Non-myeloablative SCT Utilizing Matched Family Member Stem Cells Purged Using Campath

David Rizzieri, MD

NCT00578942

COMPLETED Phase 2 47 participants

Rituximab and Combination Chemotherapy in Treating Patients With Newly Diagnosed Primary CNS Lymphoma

Alliance for Clinical Trials in Oncology

NCT00098774

COMPLETED NA 45 participants

Evaluating the Feasibility of a Digital Health Coaching Program for Individuals Following CAR T Therapy

Pack Health

NCT05064787

COMPLETED Phase 4 45 participants

Bone Marrow Transplantation in Treating Patients With Hematologic Cancer

University of Maryland, Baltimore

NCT00003398

COMPLETED Phase 1 44 participants

Radiolabeled Monoclonal Antibody Therapy and High-Dose Chemotherapy Followed By Autologous Peripheral Stem Cell Transplant in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma

Northwestern University

NCT00058292

COMPLETED Phase 2 42 participants

Autologous Stem Cell Transplant in Treating Patients With Progressive or Recurrent Hodgkin's Lymphoma

Case Comprehensive Cancer Center

NCT00265889

COMPLETED Phase 1 41 participants

T-Regulatory Cell Infusion Post Umbilical Cord Blood Transplant in Patients With Advanced Hematologic Cancer

Masonic Cancer Center, University of Minnesota

NCT00602693

COMPLETED Phase 1 40 participants

Total Body Irradiation With Fludarabine Followed by Combined Umbilical Cord Blood (UCB) Transplants

Duke University

NCT00606437

COMPLETED Phase 2 39 participants

Rituximab in Treating Patients With Non-Hodgkin's Lymphoma or Hodgkin's Disease

Alliance for Clinical Trials in Oncology

NCT00003849

COMPLETED Phase 2 39 participants

Rituximab in Treating Patients With Hodgkin's Lymphoma

Ranjana Advani

NCT00003820

COMPLETED NA 39 participants

Donor Lymphocyte Infusion in Treating Patients With Recurrent or Persistent Hematologic Cancer After Donor Stem Cell Transplant

Roswell Park Cancer Institute

NCT00534118

COMPLETED NA 37 participants

Exercise Program for Adolescents and Young Adults With Cancer

M.D. Anderson Cancer Center

NCT00502749

COMPLETED 36 participants

Long-Term Effects of Iodine I Tositumomab and Autologous Bone Marrow or Stem Cell Transplantation in Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma

Fred Hutchinson Cancer Center

NCT00098566

COMPLETED Phase 2 35 participants

Ixabepilone in Treating Patients With Relapsed or Refractory Lymphoproliferative Disorders

Memorial Sloan Kettering Cancer Center

NCT00052572

COMPLETED Phase 2 35 participants

Gallium Nitrate in Treating Patients With AIDS-Related Non-Hodgkin's Lymphoma

Roswell Park Cancer Institute

NCT00002578

COMPLETED Phase 2 35 participants

506U78 in Treating Patients With Refractory or Relapsed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

National Cancer Institute (NCI)

NCT00003545

COMPLETED Phase 1 35 participants

Study of AR-12 (2-Amino-N-[4-[5-(2 Phenanthrenyl)-3-(Trifluoromethyl)-1H-pyrazol-1-yl] Phenyl]-Acetamide) in Adult Patients With Advanced or Recurrent Solid Tumors or Lymphoma

Arno Therapeutics

NCT00978523

COMPLETED Phase 1 35 participants

VNP40101M in Treating Patients With Richter Syndrome or Refractory or Relapsed Chronic Lymphocytic Leukemia or Other Lymphoproliferative Disorders

Vion Pharmaceuticals

NCT00304005

COMPLETED Phase 2 34 participants

Rituximab and Combination Chemotherapy in Treating Patients With Newly Diagnosed, HIV-Associated Burkitt's Lymphoma

AIDS Malignancy Consortium

NCT00392834

COMPLETED Phase 2 34 participants

Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer

Case Comprehensive Cancer Center

NCT00054327

COMPLETED Phase 2 34 participants

S0350 Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage II, Stage III, or Stage IV Peripheral T-Cell Non-Hodgkin's Lymphoma

SWOG Cancer Research Network

NCT00109928

COMPLETED Phase 2 34 participants

Campath-1H + FK506 and Methylprednisolone for GVHD

Case Comprehensive Cancer Center

NCT00109993

COMPLETED Phase 2 33 participants

Lenalidomide in Treating Patients With Relapsed Mycosis Fungoides/Sezary Syndrome

Northwestern University

NCT00466921

COMPLETED Phase 1 32 participants

Study of TRPH-222 in Patients With Relapsed and/or Refractory B-Cell Lymphoma

Triphase Research and Development III

NCT03682796

COMPLETED Phase 2 32 participants

Sirolimus, Tacrolimus, and Antithymocyte Globulin in Preventing Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant For Hematological Cancer

City of Hope Medical Center

NCT00589563

COMPLETED Phase 1 32 participants

Rituxan and BEAM With Autologous Peripheral Blood Progenitor Transplant for Indolent Lymphoma

University of Nebraska

NCT00572013

COMPLETED Phase 2 32 participants

Ixazomib Rollover Study

Takeda

NCT02924272

COMPLETED 31 participants

Immune Reconstitution in Oncology Patients Following Autologous Stem Cell Transplant

St. Jude Children's Research Hospital

NCT01540175

COMPLETED Phase 2 30 participants

Galiximab in Treating Patients With Relapsed or Refractory Hodgkin's Lymphoma

Alliance for Clinical Trials in Oncology

NCT00516217

COMPLETED Early Phase 1 30 participants

Pilot Study of Non-Myeloablative, HLA-Matched Allogeneic Stem Cell Transplantation for Pediatric Hematopoietic Malignancies

National Cancer Institute (NCI)

NCT00013533

COMPLETED Phase 1 30 participants

Trial of Vorinostat in Combination With Cyclophosphamide, Etoposide, Prednisone and Rituximab for Elderly Patients With Relapsed Diffuse Large B-Cell Lymphoma (DLBCL)

Memorial Sloan Kettering Cancer Center

NCT00667615

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Phase Distribution

PhaseTrial count
Phase 1 119
Phase 2 110
Phase 3 22
Phase 4 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Lymphoma Trial Landscape

330 indexed Lymphoma studies · 88 recruiting (27%).

Phase mix: 25 late (III/IV) vs 229 early (I/II).

Top sponsor: Memorial Sloan Kettering Cancer Center (34 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Lymphoma?

PlainTrial tracks 330 US clinical trials for Lymphoma, of which 88 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Lymphoma?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.