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NCT00054327 · ClinicalTrials.gov registry record · Phase 2

Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer

A Phase 2 study of Lymphoma and Leukemia, sponsored by Case Comprehensive Cancer Center.

Completed
Registry status
Phase 2
Development phase
34
Enrollment target
1
Study location

NCT00054327 is a Phase 2 study of Lymphoma and Leukemia that has completed, run by Case Comprehensive Cancer Center. The registered enrollment target is 34 participants, below the 484-participant average among 299 other Lymphoma trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00054327, a Phase 2 study of Lymphoma and Leukemia, has completed, sponsored by Case Comprehensive Cancer Center.

COMPLETED
Registry status
Phase 2
Development phase
34 participants
Enrollment target
1
Study location

Study Summary

RATIONALE: Giving chemotherapy and total-body irradiation before a donor peripheral stem cell transplant helps stop the growth of cancer and abnormal cells and helps stop the patient's immune system from rejecting the donor's stem cells. When the stem cells from a related donor, that do not exactly match the patient's blood, are infused into the patient they may help the patient's bone marrow make stem cells, red blood cells, white blood cells, and platelets. PURPOSE: This phase II trial is studying how well giving chemotherapy with or without radiation therapy followed by donor stem cell transplant works in treating patients with hematologic cancer.

Interventions

  • DRUG Etoposide
  • DRUG cyclophosphamide
  • RADIATION radiation therapy
  • DRUG cytarabine
  • DRUG busulfan

Study Locations (1)

Ohio

  • Case Medical Center, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center - Cleveland

Trial Details

FieldValue
Enrollment Target 34 participants
Start Date 2000-11
Est. Completion 2011-09
Phase Phase 2

Sponsor

Case Comprehensive Cancer Center

407 total trials

What the Registry Record Tells You About NCT00054327

The ClinicalTrials.gov registry entry for NCT00054327 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 34 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 484-participant average among 299 other Lymphoma trials with a reported enrollment target (93% lower). The listed sponsor is Case Comprehensive Cancer Center, which has 407 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Lymphoma appearing as the primary indexed condition, and to 5 interventions - of which Etoposide is the first listed.

NCT00054327 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.

Frequently Asked Questions

What is clinical trial NCT00054327 about?

NCT00054327 is a clinical study titled "Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer". RATIONALE: Giving chemotherapy and total-body irradiation before a donor peripheral stem cell transplant helps stop the growth of cancer and abnormal cells and helps stop the patient's immune system from rejecting the donor's stem cells. When the stem cells from a related donor, that do not exactly ...

What is the current status of trial NCT00054327?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 34 participants. The study started on 2000-11. Estimated completion is 2011-09.

What conditions does trial NCT00054327 study?

This clinical trial studies the following conditions: Lymphoma, Leukemia, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Diseases.

What interventions are being tested in trial NCT00054327?

The interventions under investigation include: Etoposide (DRUG), cyclophosphamide (DRUG), radiation therapy (RADIATION), cytarabine (DRUG), busulfan (DRUG).

Who is sponsoring clinical trial NCT00054327?

This trial is sponsored by Case Comprehensive Cancer Center, which has 407 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00054327 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.