UNC Lineberger Comprehensive Cancer Center
UNC Lineberger Comprehensive Cancer Center sponsors 366 registered US clinical trials on ClinicalTrials.gov, 79 of them currently recruiting, and 209 completed. 2 of these trials are in Phase 3-4 (later-stage) and 157 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Breast Cancer, with 29 trials.
Trial Pipeline
366 total, page 1 of 8
Artificial Intelligence (AI)-Enhanced Pretreatment Peer-review Process to Improve Patient Safety in Radiation Oncology
NCT07463833
Tirzepatide in Obesity-Driven Endometrial Cancer
NCT07065552
Pilot Study of Communication for Dual Users of Cigarettes and E-cigarettes
NCT07599462
HomeGrown: A Family-based Lifestyle Intervention to Support Healthy Development of Young Children With Down Syndrome
NCT07296861
Preoperative Chemotherapy, Pembrolizumab and Low or High Dose RADiation in an Expansion Cohort of Node(+), Triple Negative Breast Cancer
NCT07276880
Local Radiofrequency Ablation Plus External Beam Radiation for the Treatment of Painful Thoracic and Lumbar Spine Tumors
NCT07479199
PREDICT-RD: ctDNA Surveillance in TNBC With Residual Disease
NCT07069595
Evolutionary Clinical Trial for Novel Biomarker-Driven Therapies
NCT07340541
Hyaluronic Acid-based Gel Spacers in Gynecologic Malignancies
NCT07292818
Sparing Parotid Ducts Via MRI Sialography for Reduced Patient-Reported Xerostomia
NCT07278557
Nutrition Awareness Among Women With Non-Metastatic Breast Cancer
NCT07389967
Feasibility of Symptom Management for Patients With Metastatic Breast Cancer to Increase Exercise
NCT07313306
Medically Tailored Meals for Kids
NCT06814795
Translation of Acoustic Angiography: Contrast Enhanced Super Resolution (CESR) Imaging
NCT07225114
Using Tailored mHealth Strategies to Promote Weight Management Among Adolescent and Young Adult Cancer Survivors
NCT06848491
Consumer Perceptions of Alcoholic Beverages
NCT07226271
Perceived Effectiveness of Vaping Prevention Ads Among Adolescents and Young Adults
NCT07116837
Dissemination of BREASTChoice AIM1-B
NCT07396766
Molecular Residual Disease Assessment in a Representative Diverse Population of Patients With Early-stage Breast Cancer
NCT07025785
Expanding the Support of Family Caregivers of Diverse Patients With Cancer and Diabetes
NCT07061652
PROGRESS: Precision Oncology Using Genomic Reflexive Evaluations for Study Selection and Survival
NCT06896162
mPATH-Cloud for Colorectal Cancer Screening
NCT06441487
Combating Cancer-Related Fatigue: A Personalized Supportive Care Program
NCT06860880
XL092 and Cemiplimab in BRAF WT Thyroid Cancer
NCT06902376
Implementation of an Oral Chemotherapy Adherence Intervention
NCT06989489
Memantine and Exercise to Improve Cognitive Function and Modulate Biological Pathways of Cognitive Decline During Chemotherapy in Breast Cancer
NCT06727773
Designing Visual Tools to Enhance Cancer Surgeon Decision-making
NCT06965192
Digital Art Therapy for Young Cancer Survivors
NCT06789666
Ultra Hypo-fractionated Adjuvant Whole Breast Radiation Therapy With Simultaneous Integrated Boost for Early-Stage Breast Cancer (H-ASSIST)
NCT06902311
VisR Ultrasound for Noninvasively Interrogating Stromal Collagen Organization in Women as a Breast Cancer Biomarker: Evaluation of Anisotropy in Cancer Patients
NCT06878547
Effectiveness of Central Oncology Navigation and the Use of an ORN
NCT06618274
Basal-like PDAC Treated With Gemcitabine, Erlotinib, and Nab-paclitaxel
NCT06483555
Rehabilitation Outcomes Study
NCT06674889
Promoting Resilience in Women With Breast Cancer (PRISM -MBC)
NCT06855654
A Novel Approach Utilizing Organ Specific Age Proteomics
NCT06789653
Multimedia Aid for Genetic Testing in Gynecologic Oncology
NCT07084168
BREAST Choice Decision Tool R21 - AIM2
NCT06817226
Autologous CAR-T Cells Targeting B7H3 in Ovarian Cancer iC9-CAR.B7-H3 T Cells
NCT06305299
Autologous CAR-T Cells Targeting B7-H3 in PDAC
NCT06158139
Study of Autologous CAR-T Cells Targeting B7-H3 in TNBC iC9-CAR.B7-H3 T Cells
NCT06347068
DISCOVERY: Evaluating a Decision Support Tool for Adults Seen in Hematology/Oncology Clinics
NCT06296368
Blood and Urine HPVDNA as Minimally Invasive Biomarkers for Cervical Cancer Detection and Surveillance Following Treatment
NCT04743674
ATLCAR.CD30.CCR4 for CD30+ HL ATLCAR.CD30.CCR4 Cells
NCT06090864
UNC Metastatic Cancer Radiation Therapy Registry
NCT06306924
Autologous CAR-T Cells Targeting CSPG4 in Relapsed/Refractory HNSCC
NCT06096038
Promoting CT Engagement for Pancreatic Cancer With App
NCT06252545
The Effects of SCFA Supplementation in Subjects Receiving Abdominopelvic RT: A Randomized Controlled Study
NCT04700527
Integrating Biological, Clinical, and Behavioral Factors to Improve Breast Cancer Outcomes - Carolina Breast Cancer Study
NCT07214610
Improving Thoracic Surgical Care Using Electronic Patient-Reported Outcomes (ePROS)
NCT06075316
GRID Therapy for Extremity Soft Tissue Sarcoma
NCT06073067
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 71 |
| Phase 2 | 86 |
| Phase 3 | 1 |
| Phase 4 | 1 |
Therapeutic Areas
What the Pipeline for UNC Lineberger Comprehensive Cancer Center Shows
According to the ClinicalTrials.gov registry, UNC Lineberger Comprehensive Cancer Center is linked to 366 US clinical trials across every stage of research activity. Of those, 79 studies are currently recruiting, about 22% of the sponsor's indexed portfolio, and 209 are already marked complete, representing roughly 57% of the total.
The phase mix for UNC Lineberger Comprehensive Cancer Center reports 2 late-stage studies (Phase 3 and Phase 4 combined) and 157 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for UNC Lineberger Comprehensive Cancer Center is Breast Cancer with 29 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.