UNC Lineberger Comprehensive Cancer Center

366 total trials 79 currently recruiting 209 completed

UNC Lineberger Comprehensive Cancer Center sponsors 366 registered US clinical trials on ClinicalTrials.gov, 79 of them currently recruiting, and 209 completed. 2 of these trials are in Phase 3-4 (later-stage) and 157 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Breast Cancer, with 29 trials.

Trial Pipeline

366 total, page 1 of 8

RECRUITING NA

Artificial Intelligence (AI)-Enhanced Pretreatment Peer-review Process to Improve Patient Safety in Radiation Oncology

NCT07463833

RECRUITING Early Phase 1

Tirzepatide in Obesity-Driven Endometrial Cancer

NCT07065552

RECRUITING NA

Pilot Study of Communication for Dual Users of Cigarettes and E-cigarettes

NCT07599462

RECRUITING NA

HomeGrown: A Family-based Lifestyle Intervention to Support Healthy Development of Young Children With Down Syndrome

NCT07296861

RECRUITING Phase 2

Preoperative Chemotherapy, Pembrolizumab and Low or High Dose RADiation in an Expansion Cohort of Node(+), Triple Negative Breast Cancer

NCT07276880

RECRUITING

Local Radiofrequency Ablation Plus External Beam Radiation for the Treatment of Painful Thoracic and Lumbar Spine Tumors

NCT07479199

RECRUITING Phase 2

PREDICT-RD: ctDNA Surveillance in TNBC With Residual Disease

NCT07069595

RECRUITING Phase 2

Evolutionary Clinical Trial for Novel Biomarker-Driven Therapies

NCT07340541

RECRUITING Phase 1

Hyaluronic Acid-based Gel Spacers in Gynecologic Malignancies

NCT07292818

RECRUITING Phase 2

Sparing Parotid Ducts Via MRI Sialography for Reduced Patient-Reported Xerostomia

NCT07278557

RECRUITING NA

Nutrition Awareness Among Women With Non-Metastatic Breast Cancer

NCT07389967

RECRUITING NA

Feasibility of Symptom Management for Patients With Metastatic Breast Cancer to Increase Exercise

NCT07313306

RECRUITING NA

Medically Tailored Meals for Kids

NCT06814795

RECRUITING Phase 2

Translation of Acoustic Angiography: Contrast Enhanced Super Resolution (CESR) Imaging

NCT07225114

RECRUITING NA

Using Tailored mHealth Strategies to Promote Weight Management Among Adolescent and Young Adult Cancer Survivors

NCT06848491

RECRUITING NA

Consumer Perceptions of Alcoholic Beverages

NCT07226271

RECRUITING NA

Perceived Effectiveness of Vaping Prevention Ads Among Adolescents and Young Adults

NCT07116837

RECRUITING NA

Dissemination of BREASTChoice AIM1-B

NCT07396766

RECRUITING NA

Molecular Residual Disease Assessment in a Representative Diverse Population of Patients With Early-stage Breast Cancer

NCT07025785

RECRUITING NA

Expanding the Support of Family Caregivers of Diverse Patients With Cancer and Diabetes

NCT07061652

RECRUITING NA

PROGRESS: Precision Oncology Using Genomic Reflexive Evaluations for Study Selection and Survival

NCT06896162

RECRUITING NA

mPATH-Cloud for Colorectal Cancer Screening

NCT06441487

RECRUITING NA

Combating Cancer-Related Fatigue: A Personalized Supportive Care Program

NCT06860880

RECRUITING Phase 1

XL092 and Cemiplimab in BRAF WT Thyroid Cancer

NCT06902376

RECRUITING NA

Implementation of an Oral Chemotherapy Adherence Intervention

NCT06989489

RECRUITING Phase 2

Memantine and Exercise to Improve Cognitive Function and Modulate Biological Pathways of Cognitive Decline During Chemotherapy in Breast Cancer

NCT06727773

RECRUITING NA

Designing Visual Tools to Enhance Cancer Surgeon Decision-making

NCT06965192

RECRUITING NA

Digital Art Therapy for Young Cancer Survivors

NCT06789666

RECRUITING Phase 2

Ultra Hypo-fractionated Adjuvant Whole Breast Radiation Therapy With Simultaneous Integrated Boost for Early-Stage Breast Cancer (H-ASSIST)

NCT06902311

RECRUITING

VisR Ultrasound for Noninvasively Interrogating Stromal Collagen Organization in Women as a Breast Cancer Biomarker: Evaluation of Anisotropy in Cancer Patients

NCT06878547

RECRUITING NA

Effectiveness of Central Oncology Navigation and the Use of an ORN

NCT06618274

RECRUITING Phase 1

Basal-like PDAC Treated With Gemcitabine, Erlotinib, and Nab-paclitaxel

NCT06483555

RECRUITING NA

Rehabilitation Outcomes Study

NCT06674889

RECRUITING NA

Promoting Resilience in Women With Breast Cancer (PRISM -MBC)

NCT06855654

RECRUITING

A Novel Approach Utilizing Organ Specific Age Proteomics

NCT06789653

RECRUITING NA

Multimedia Aid for Genetic Testing in Gynecologic Oncology

NCT07084168

RECRUITING NA

BREAST Choice Decision Tool R21 - AIM2

NCT06817226

RECRUITING Phase 1

Autologous CAR-T Cells Targeting B7H3 in Ovarian Cancer iC9-CAR.B7-H3 T Cells

NCT06305299

RECRUITING Phase 1

Autologous CAR-T Cells Targeting B7-H3 in PDAC

NCT06158139

RECRUITING Phase 1

Study of Autologous CAR-T Cells Targeting B7-H3 in TNBC iC9-CAR.B7-H3 T Cells

NCT06347068

RECRUITING NA

DISCOVERY: Evaluating a Decision Support Tool for Adults Seen in Hematology/Oncology Clinics

NCT06296368

RECRUITING

Blood and Urine HPVDNA as Minimally Invasive Biomarkers for Cervical Cancer Detection and Surveillance Following Treatment

NCT04743674

RECRUITING Phase 1

ATLCAR.CD30.CCR4 for CD30+ HL ATLCAR.CD30.CCR4 Cells

NCT06090864

RECRUITING

UNC Metastatic Cancer Radiation Therapy Registry

NCT06306924

RECRUITING Phase 1

Autologous CAR-T Cells Targeting CSPG4 in Relapsed/Refractory HNSCC

NCT06096038

RECRUITING NA

Promoting CT Engagement for Pancreatic Cancer With App

NCT06252545

RECRUITING Phase 1

The Effects of SCFA Supplementation in Subjects Receiving Abdominopelvic RT: A Randomized Controlled Study

NCT04700527

RECRUITING NA

Integrating Biological, Clinical, and Behavioral Factors to Improve Breast Cancer Outcomes - Carolina Breast Cancer Study

NCT07214610

RECRUITING NA

Improving Thoracic Surgical Care Using Electronic Patient-Reported Outcomes (ePROS)

NCT06075316

RECRUITING NA

GRID Therapy for Extremity Soft Tissue Sarcoma

NCT06073067

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Phase Distribution

PhaseTrial count
Phase 1 71
Phase 2 86
Phase 3 1
Phase 4 1

What the Pipeline for UNC Lineberger Comprehensive Cancer Center Shows

According to the ClinicalTrials.gov registry, UNC Lineberger Comprehensive Cancer Center is linked to 366 US clinical trials across every stage of research activity. Of those, 79 studies are currently recruiting, about 22% of the sponsor's indexed portfolio, and 209 are already marked complete, representing roughly 57% of the total.

The phase mix for UNC Lineberger Comprehensive Cancer Center reports 2 late-stage studies (Phase 3 and Phase 4 combined) and 157 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for UNC Lineberger Comprehensive Cancer Center is Breast Cancer with 29 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.