UNC Lineberger Comprehensive Cancer Center
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, UNC Lineberger Comprehensive Cancer Center sits in the top decile of US sponsors by registered trial count (#97 of 15,742 sponsors by registered trial count).
UNC Lineberger Comprehensive Cancer Center: 366 sponsored US clinical trials, 79 recruiting.
UNC Lineberger Comprehensive Cancer Center sponsors 366 registered US clinical trials on ClinicalTrials.gov, 79 of them currently recruiting, and 209 completed. 2 of these trials are in Phase 3-4 (later-stage) and 157 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Breast Cancer, with 29 trials.
Top-decile sponsor footprint
UNC Lineberger Comprehensive Cancer Center ranks in the top decile of sponsors by registered trial count (#97 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
209 of 246 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (85.0%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
366 total, page 1 of 8
Artificial Intelligence (AI)-Enhanced Pretreatment Peer-review Process to Improve Patient Safety in Radiation Oncology
NCT07463833
Tirzepatide in Obesity-Driven Endometrial Cancer
NCT07065552
Pilot Study of Communication for Dual Users of Cigarettes and E-cigarettes
NCT07599462
HomeGrown: A Family-based Lifestyle Intervention to Support Healthy Development of Young Children With Down Syndrome
NCT07296861
Preoperative Chemotherapy, Pembrolizumab and Low or High Dose RADiation in an Expansion Cohort of Node(+), Triple Negative Breast Cancer
NCT07276880
Local Radiofrequency Ablation Plus External Beam Radiation for the Treatment of Painful Thoracic and Lumbar Spine Tumors
NCT07479199
PREDICT-RD: ctDNA Surveillance in TNBC With Residual Disease
NCT07069595
Evolutionary Clinical Trial for Novel Biomarker-Driven Therapies
NCT07340541
Hyaluronic Acid-based Gel Spacers in Gynecologic Malignancies
NCT07292818
Sparing Parotid Ducts Via MRI Sialography for Reduced Patient-Reported Xerostomia
NCT07278557
Nutrition Awareness Among Women With Non-Metastatic Breast Cancer
NCT07389967
Feasibility of Symptom Management for Patients With Metastatic Breast Cancer to Increase Exercise
NCT07313306
Medically Tailored Meals for Kids
NCT06814795
Translation of Acoustic Angiography: Contrast Enhanced Super Resolution (CESR) Imaging
NCT07225114
Using Tailored mHealth Strategies to Promote Weight Management Among Adolescent and Young Adult Cancer Survivors
NCT06848491
Consumer Perceptions of Alcoholic Beverages
NCT07226271
Perceived Effectiveness of Vaping Prevention Ads Among Adolescents and Young Adults
NCT07116837
Dissemination of BREASTChoice AIM1-B
NCT07396766
Molecular Residual Disease Assessment in a Representative Diverse Population of Patients With Early-stage Breast Cancer
NCT07025785
Expanding the Support of Family Caregivers of Diverse Patients With Cancer and Diabetes
NCT07061652
PROGRESS: Precision Oncology Using Genomic Reflexive Evaluations for Study Selection and Survival
NCT06896162
mPATH-Cloud for Colorectal Cancer Screening
NCT06441487
Combating Cancer-Related Fatigue: A Personalized Supportive Care Program
NCT06860880
XL092 and Cemiplimab in BRAF WT Thyroid Cancer
NCT06902376
Implementation of an Oral Chemotherapy Adherence Intervention
NCT06989489
Memantine and Exercise to Improve Cognitive Function and Modulate Biological Pathways of Cognitive Decline During Chemotherapy in Breast Cancer
NCT06727773
Designing Visual Tools to Enhance Cancer Surgeon Decision-making
NCT06965192
Digital Art Therapy for Young Cancer Survivors
NCT06789666
Ultra Hypo-fractionated Adjuvant Whole Breast Radiation Therapy With Simultaneous Integrated Boost for Early-Stage Breast Cancer (H-ASSIST)
NCT06902311
VisR Ultrasound for Noninvasively Interrogating Stromal Collagen Organization in Women as a Breast Cancer Biomarker: Evaluation of Anisotropy in Cancer Patients
NCT06878547
Effectiveness of Central Oncology Navigation and the Use of an ORN
NCT06618274
Basal-like PDAC Treated With Gemcitabine, Erlotinib, and Nab-paclitaxel
NCT06483555
Rehabilitation Outcomes Study
NCT06674889
Promoting Resilience in Women With Breast Cancer (PRISM -MBC)
NCT06855654
A Novel Approach Utilizing Organ Specific Age Proteomics
NCT06789653
Multimedia Aid for Genetic Testing in Gynecologic Oncology
NCT07084168
BREAST Choice Decision Tool R21 - AIM2
NCT06817226
Autologous CAR-T Cells Targeting B7H3 in Ovarian Cancer iC9-CAR.B7-H3 T Cells
NCT06305299
Autologous CAR-T Cells Targeting B7-H3 in PDAC
NCT06158139
Study of Autologous CAR-T Cells Targeting B7-H3 in TNBC iC9-CAR.B7-H3 T Cells
NCT06347068
DISCOVERY: Evaluating a Decision Support Tool for Adults Seen in Hematology/Oncology Clinics
NCT06296368
Blood and Urine HPVDNA as Minimally Invasive Biomarkers for Cervical Cancer Detection and Surveillance Following Treatment
NCT04743674
ATLCAR.CD30.CCR4 for CD30+ HL ATLCAR.CD30.CCR4 Cells
NCT06090864
UNC Metastatic Cancer Radiation Therapy Registry
NCT06306924
Autologous CAR-T Cells Targeting CSPG4 in Relapsed/Refractory HNSCC
NCT06096038
Promoting CT Engagement for Pancreatic Cancer With App
NCT06252545
The Effects of SCFA Supplementation in Subjects Receiving Abdominopelvic RT: A Randomized Controlled Study
NCT04700527
Integrating Biological, Clinical, and Behavioral Factors to Improve Breast Cancer Outcomes - Carolina Breast Cancer Study
NCT07214610
Improving Thoracic Surgical Care Using Electronic Patient-Reported Outcomes (ePROS)
NCT06075316
GRID Therapy for Extremity Soft Tissue Sarcoma
NCT06073067
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 71 |
| Phase 2 | 86 |
| Phase 3 | 1 |
| Phase 4 | 1 |
Therapeutic Areas
What is open in the UNC Lineberger Comprehensive Cancer Center pipeline
79 recruiting of 366 indexed (22% open); 209 completed (57%).
Phase mix: 2 late (III/IV) vs 157 early (I/II) (early-phase heavy).
Top condition: Breast Cancer (29 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
UNC Lineberger Comprehensive Cancer Center: open-pipeline peers nationwide
Peers matched on 366 registered trials and 22% open enrollment, not the therapeutic-area sidebar.
UNC Lineberger Comprehensive Cancer Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 366 trials (± recruiting share)
- Roswell Park Cancer Institute · 365 trials · 16% recruiting
- University of California, Irvine · 368 trials · 20% recruiting
- New York State Psychiatric Institute · 364 trials · 3% recruiting
- Northwell Health · 370 trials · 22% recruiting
Sponsors near 22% open enrollment (± trial volume)
- Women and Infants Hospital of Rhode Island · 22% recruiting · 65 trials
- Merck Sharp & Dohme · 22% recruiting · 558 trials
- Henry M. Jackson Foundation for the Advancement of Military Medicine · 22% recruiting · 60 trials
- AbbVie · 21% recruiting · 526 trials
Related
What to do with this UNC Lineberger Comprehensive Cancer Center page
366 registered trials is a research-attention snapshot, not an endorsement of UNC Lineberger Comprehensive Cancer Center or any single study.
- 79 of UNC Lineberger Comprehensive Cancer Center's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Breast Cancer is the condition UNC Lineberger Comprehensive Cancer Center studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Breast Cancer trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
UNC Lineberger Comprehensive Cancer Center pipeline card: 366 registered trials from official public datasets.Report a data error.